• 四川大學(xué)華西醫(yī)院放射科（成都，610041）;

【摘要】 伴隨多層螺旋CT和MRI檢查技術(shù)的發(fā)展，多層螺旋CT和MRI在小腸克羅恩病的影像學(xué)研究和臨床應(yīng)用中日益增多，在評價小腸克羅恩病腸壁炎癥程度、腸周情況、腸系膜異常及周圍淋巴結(jié)腫大方面明顯優(yōu)于傳統(tǒng)X線小腸氣鋇雙重造影。多層螺旋CT和MRI被廣泛應(yīng)用于小腸克羅恩病的臨床診斷及治療后評價。

引用本文： 王成龍,伍兵. 小腸克羅恩病的CT和MRI研究進(jìn)展. 華西醫(yī)學(xué), 2011, 26(1): 133-135. doi: 復(fù)制

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1. 　Horsthuis K, Lavini Mphil C, Stoker J, et al. MRI in Crohn’s disease [J]. Magn Reson Imaging, 2005, 22(1): 1-12.
2. 　Paulsen SR, Huprich JE, Fletcher JG, et al. CT enterography as a diagnostic tool in evaluating small bowel disorders: review of clinical experience with over 700 cases [J]. Radiographics, 2006, 26(3): 641-662.
3. 　Miomrdi LM, Vecchioi A, Guidi L, et al. CT findings and clinical activity in Crohn’s disease [J]. Clinical Imaging, 2009, 33(2): 123-129.
4. 　Zhang LH, Zhang SZ, Hu HJ. Multi-detector enterography with iso-osmotic mannitol as oral contrast for detecting small bowel disease [J]. World J Gastroenterol, 2005, 11(15): 2324-2329.
5. 　張崤魏, 張士正, 任小軍. 磁共振成像小腸造影[J]. 中國醫(yī)學(xué)計(jì)算機(jī)成像雜志, 2008, 14(6): 578-580.
6. 　Zamboni GA, Raptopouluos V. CT enterography [J]. Gastrointest Endosc Clin N Am, 2010, 20(2): 347-366.
7. 　Hara AK, Russell SA, Heigh I, et al. Using enterography to monitor crohn’s disease activity: a preliminary study [J]. American Journal Radiology, 2008, 190(6): 1512-1516.
8. 　Baker ME, Walter J, Obuchowski ME, et al. Mural attenuation in normal small bowel and active inflammatory Cronhn’s disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness [J]. American Journal Radiology, 2009, 192: 417-423.
9. 　Peset, Valencia, Eapana. Ultrasound, CT, and MRI in Crohn disease [J]. Radiologia, 2007, 49(2): 97-108.
10. 　魯桂青, 劉林祥, 陳克敏, 等. 多層螺旋CT在小腸 Crohn病中的應(yīng)用研究[J]. 中華放射學(xué)雜志, 2009, 43(4): 373-377.
11. 　Paolotoma P, Granata C, Magnano G, et al. CT and MRI of peadiatric Crohn disease [J]. Pediatrc Radiology, 2007, 37(11): 1083-1092.
12. 　Marc D, Kohli D, Maglintel T. CT enteroclysis in small bowel Crohn’s disease [J]. European Journal Radiology, 2009, 69(3): 393-397.
13. 　Fidler Jl, Guimaraes L, David M, et al. MR Imaging of the small bowel [J]. Radiographics, 2009, 29(6): 1811-25.
14. 　Masselli G, Vcchiolo A, Guadi F, et al. Crohn disease of the small bowel: MR enteroclysis versus conventional enteroclysis [J]. Abdom Imagimg, 2006, 31 (4): 400-409.
15. 　Papanikolaou N, Prassopoulos P, Grammatikskis J, et al. Optimization of a contrast medium suitable for conventionalenteroclysis, MR enteroclysis, and virtual MR enteroscopy [J]. Abdom Imaging, 2002, 27(5): 517-522.
16. 　Daguia C, Sitchfield M, Kean M. Feasibility of 3-T MRI for the evaluation of Crohn disease in children [J]. Pediatr Radiology, 2010, 40(10): 1615-1624.
17. 　Gourtsoyiannis Nc, Papanikolaou N, Karantanas A. Magnetic resonance enteroclysis in the diagnosis of small-intestinal Crohn’s disease [J]. Clinical Gastroenrerology, 2006, 47(10): 1008-1016.
18. 　Florie J, Horsthuis KW, Hommes DW, et al. Magnetic resonance imaging compared with ileocolonoscopy in evaluating disease severity in Crohn’s disease [J], Clinical Gastroenterology Hepatology, 2005, 3(12): 1221-1228.
19. 　Rottgen R, Grandkle T, Grieser C, et al. Measurement of MRI enhancement kinetics for evaluation of inflammatory activity in Crohn’s disease [J]. Clinical Imaging, 2010, 34(1): 29-35.
20. 　Siddiki H, Fidler J. MR imaging of the small bowel in Crohn’s disease [J]. Uropean Jouenal Radiology, 2009, 69(3): 409-417.
21. 　Maccioni F. Double-contrast magnetic resonance imaging of the small and large bowel effectiveness in the evaluation of inflammatory bowel disease [J]. Abdominal Imaging, 2008, 35(1): 31-40.
22. 　Bruining DH, Siddki HA, Fletcher JG, et al. Prevalence of penetrating disease and extraintesinal manifestions of Crohn’s disease detected with CT enterography [J]. Inflammatory Bowel Diseases, 2008, 14(12): 1701-1706.
23. 　Horsthuis K, Bipat S, Bennink RJ, et al. Inflammatory bowel didsease diagnosed with US, MR, scintigraphy, and CT: meta-analysis of prospective studies [J]. Radiology, 2008, 247(1): 64-79.
  1. 1. 　Horsthuis K, Lavini Mphil C, Stoker J, et al. MRI in Crohn’s disease [J]. Magn Reson Imaging, 2005, 22(1): 1-12.
  2. 2. 　Paulsen SR, Huprich JE, Fletcher JG, et al. CT enterography as a diagnostic tool in evaluating small bowel disorders: review of clinical experience with over 700 cases [J]. Radiographics, 2006, 26(3): 641-662.
  3. 3. 　Miomrdi LM, Vecchioi A, Guidi L, et al. CT findings and clinical activity in Crohn’s disease [J]. Clinical Imaging, 2009, 33(2): 123-129.
  4. 4. 　Zhang LH, Zhang SZ, Hu HJ. Multi-detector enterography with iso-osmotic mannitol as oral contrast for detecting small bowel disease [J]. World J Gastroenterol, 2005, 11(15): 2324-2329.
  5. 5. 　張崤魏, 張士正, 任小軍. 磁共振成像小腸造影[J]. 中國醫(yī)學(xué)計(jì)算機(jī)成像雜志, 2008, 14(6): 578-580.
  6. 6. 　Zamboni GA, Raptopouluos V. CT enterography [J]. Gastrointest Endosc Clin N Am, 2010, 20(2): 347-366.
  7. 7. 　Hara AK, Russell SA, Heigh I, et al. Using enterography to monitor crohn’s disease activity: a preliminary study [J]. American Journal Radiology, 2008, 190(6): 1512-1516.
  8. 8. 　Baker ME, Walter J, Obuchowski ME, et al. Mural attenuation in normal small bowel and active inflammatory Cronhn’s disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness [J]. American Journal Radiology, 2009, 192: 417-423.
  9. 9. 　Peset, Valencia, Eapana. Ultrasound, CT, and MRI in Crohn disease [J]. Radiologia, 2007, 49(2): 97-108.
  10. 10. 　魯桂青, 劉林祥, 陳克敏, 等. 多層螺旋CT在小腸 Crohn病中的應(yīng)用研究[J]. 中華放射學(xué)雜志, 2009, 43(4): 373-377.
  11. 11. 　Paolotoma P, Granata C, Magnano G, et al. CT and MRI of peadiatric Crohn disease [J]. Pediatrc Radiology, 2007, 37(11): 1083-1092.
  12. 12. 　Marc D, Kohli D, Maglintel T. CT enteroclysis in small bowel Crohn’s disease [J]. European Journal Radiology, 2009, 69(3): 393-397.
  13. 13. 　Fidler Jl, Guimaraes L, David M, et al. MR Imaging of the small bowel [J]. Radiographics, 2009, 29(6): 1811-25.
  14. 14. 　Masselli G, Vcchiolo A, Guadi F, et al. Crohn disease of the small bowel: MR enteroclysis versus conventional enteroclysis [J]. Abdom Imagimg, 2006, 31 (4): 400-409.
  15. 15. 　Papanikolaou N, Prassopoulos P, Grammatikskis J, et al. Optimization of a contrast medium suitable for conventionalenteroclysis, MR enteroclysis, and virtual MR enteroscopy [J]. Abdom Imaging, 2002, 27(5): 517-522.
  16. 16. 　Daguia C, Sitchfield M, Kean M. Feasibility of 3-T MRI for the evaluation of Crohn disease in children [J]. Pediatr Radiology, 2010, 40(10): 1615-1624.
  17. 17. 　Gourtsoyiannis Nc, Papanikolaou N, Karantanas A. Magnetic resonance enteroclysis in the diagnosis of small-intestinal Crohn’s disease [J]. Clinical Gastroenrerology, 2006, 47(10): 1008-1016.
  18. 18. 　Florie J, Horsthuis KW, Hommes DW, et al. Magnetic resonance imaging compared with ileocolonoscopy in evaluating disease severity in Crohn’s disease [J], Clinical Gastroenterology Hepatology, 2005, 3(12): 1221-1228.
  19. 19. 　Rottgen R, Grandkle T, Grieser C, et al. Measurement of MRI enhancement kinetics for evaluation of inflammatory activity in Crohn’s disease [J]. Clinical Imaging, 2010, 34(1): 29-35.
  20. 20. 　Siddiki H, Fidler J. MR imaging of the small bowel in Crohn’s disease [J]. Uropean Jouenal Radiology, 2009, 69(3): 409-417.
  21. 21. 　Maccioni F. Double-contrast magnetic resonance imaging of the small and large bowel effectiveness in the evaluation of inflammatory bowel disease [J]. Abdominal Imaging, 2008, 35(1): 31-40.
  22. 22. 　Bruining DH, Siddki HA, Fletcher JG, et al. Prevalence of penetrating disease and extraintesinal manifestions of Crohn’s disease detected with CT enterography [J]. Inflammatory Bowel Diseases, 2008, 14(12): 1701-1706.
  23. 23. 　Horsthuis K, Bipat S, Bennink RJ, et al. Inflammatory bowel didsease diagnosed with US, MR, scintigraphy, and CT: meta-analysis of prospective studies [J]. Radiology, 2008, 247(1): 64-79.