摘要:目的：探討成都地區(qū)體檢人群中丙氨酸氨基轉(zhuǎn)移酶（ALT）升高率與其升高的相關(guān)因素
,為正確分析引起ALT升高的原因提供相關(guān)依據(jù)。方法:以參與體檢的8734名體檢人群為研究
對(duì)象,收集身高、體重、血壓、丙氨酸氨基轉(zhuǎn)移酶、空腹血糖、高密度脂蛋白、低密度脂蛋
白、總膽固醇、甘油三酯、血清HBsAg、脂肪肝及膽石癥等相關(guān)資料進(jìn)行分析。結(jié)果:在全部體檢人群中,ALT升高率為1011%,男性ALT升高率為13.70%,女性ALT升高率為6.30%,男性明顯高于女性（P lt;0001）；ALT升高組的年齡均數(shù)小于ALT正常組（P lt;0001）；在ALT升高的受檢者中,脂肪肝、高脂血癥、肥胖、糖尿病、膽囊結(jié)石、飲酒及乙肝等患病率均高于ALT正常組受檢者（P lt;005）。結(jié)論:脂肪肝、糖脂代謝紊亂及乙肝是體檢人員ALT升高的主要原因；男性和低齡也是體檢者ALT升高的危險(xiǎn)因素。
Abstract: Objective: To investigate the prevalence and relative factors of elevated serum alanine aminotransferase(ALT) levels and providescientific bases for its causes analysis in physical examination people in Chengdu. Methods: Subjects who received medical examination in physical examination center of west China hospital were screened in this study. The information of height, body weight, blood pressure, serum ALT, fasting plasma glucose, highdensity lipoprotein cholesterol, lowdensity lipoprotein cholesterol, total cholesterol, triglyceride, hepatitis B surface antigen (HBsAg) statue, fatty liver and cholelithiasis were collected and analyzed. 〖WT5”HZ〗Results:〖WT5”BZ〗 A total of 8734 cases were included in this study. The total prevalence of elevated ALT was observed in 1011%, including 137% in man and 63% in woman, and this difference between man and woman was statistic significant (P＜0001). The mean age of ALT elevated group was obvious lower than that of normal ALT group (P＜0001). Interesting, the occurrence rates of fatty liver, hyperlipidemia, obesity, diabetes,gallstones, drinking and positive hepatitis B surface antigen in ALT elevated group were all significant higher than that in normal ALT group (P＜005). Conclusion: Fatty liver, glyeolipid metabolism disorder, and hepatitis B were main reasons of elevated ALT. Male and young cases were both high risk of elevat
ed ALT in this study.

引用本文： 陳學(xué)兵,陳恩強(qiáng),李紅,朱霞,唐紅. 成都地區(qū)體檢人群ALT升高相關(guān)原因分析. 華西醫(yī)學(xué), 2009, 24(12): 3132-3135. doi: 復(fù)制

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