• 四川省遂寧市人民醫(yī)院骨科,四川遂寧 629000;

目的:探討脊柱轉(zhuǎn)移瘤患者的手術(shù)切除與脊柱穩(wěn)定性重建的適應(yīng)證與效果。方法:2003年4月至2008年4月,收治了脊柱轉(zhuǎn)移癌患者32例。腫瘤轉(zhuǎn)移部位:胸椎轉(zhuǎn)移22例,腰椎轉(zhuǎn)移7例,頸椎轉(zhuǎn)移3例。男性13例,女性19例。出現(xiàn)神經(jīng)系統(tǒng)受損者27例,其中完全癱瘓者7例,不完全癱瘓者20例。全組患者均做了椎體切除、內(nèi)固定術(shù)或后路椎板切除、椎管減壓內(nèi)固定術(shù)或前后路聯(lián)合行360°脊椎切除固定一期重建脊柱穩(wěn)定性。觀察術(shù)后局部疼痛緩解,神經(jīng)功能恢復(fù)及脊柱穩(wěn)定性情況。結(jié)果:隨訪時(shí)間為6~60個(gè)月,32例患者中,30例術(shù)后痛疼得到緩解。27例有神經(jīng)功能損害的患者中,25例術(shù)后麻痹癥狀改善。3例完全癱瘓的患者中,2例在減壓術(shù)后ASIA分級(jí)提高了1~2個(gè)等級(jí)。術(shù)后影像學(xué)提示脊柱序列和椎間高度恢復(fù)。術(shù)后存活1年以上的患者22例,約占患者總數(shù)的69%。結(jié)論:外科切除與重建治療轉(zhuǎn)移癌所致椎體塌陷或不穩(wěn)定造成嚴(yán)重的神經(jīng)損害或機(jī)械性脊柱痛疼的外科療效肯定,能夠增加脊椎穩(wěn)定性,提高生存質(zhì)量。

引用本文: 張智,葉永杰,鄭佳壯,康小平. 外科切除與重建治療脊柱轉(zhuǎn)移腫瘤. 華西醫(yī)學(xué), 2009, 24(1): 90-93. doi: 復(fù)制

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4. Manabe J,Kawaguchi N,Matsumoto S,et al.Surgical treatment of bone metastasis:indications and outcomes[J].Int J Clin Oncol,2005,10(2):103-111..
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6. Chen YJ,Hsu HC,Chen KH,et al.Transpedicular partial corpectomy without anterior vertebral reconstruction in thoracic spinal metastases[J].Spine,2007 Oct 15;32(22):E6236..
7. 劉忠軍,黨耕町,馬慶軍,等.脊柱腫瘤的全脊椎切除術(shù)及脊柱穩(wěn)定性重建[J].中華骨科雜志,2001,21(11):646-649..
8. Vrionis FD,Small J.Surgical management of metastatic spinal neoplasms[J].Neurosurg Focus,2003,15(5):E12..
9. Tomita K,Kawahara N,Kobayashi T,et al.Surgical strategy for spinal metastases[J].Spine,2001,26:298-306..
10. Boriani S,Biagini R,De Iure F,et al.En bloc resections of bone tumors of the thoracolumbar spine.A preliminary report on 29 patients[J].Spine,1996,21(16):1927-1931.
  1. 1. Weigel B,Maghsudi M,Neumann C,et al.Surgical management of symptomatic spinal metastases.Postoperative outcome and quality of life[J].Spine,1999,24:2240-2246..
  2. 2. FeizErfan I,Rhines LD,Weinberg JS.The role of surgery in the management of metastatic spinal tumors[J].Semin Oncol,2008,35(2):108-117..
  3. 3. Fujimaki Y,Tsuchiya H,Kawahara N,et al.Surgical treatment for metastatic bone tumor[J].Clin Calcium,2006,16(4):647-654..
  4. 4. Manabe J,Kawaguchi N,Matsumoto S,et al.Surgical treatment of bone metastasis:indications and outcomes[J].Int J Clin Oncol,2005,10(2):103-111..
  5. 5. Bilsky MH,Boakye M,Collignon F,et al.Operative management of metastatic and malignant primary subaxial cervical tumors[J].J Neurosurg Spine,2005,2(3):256-264..
  6. 6. Chen YJ,Hsu HC,Chen KH,et al.Transpedicular partial corpectomy without anterior vertebral reconstruction in thoracic spinal metastases[J].Spine,2007 Oct 15;32(22):E6236..
  7. 7. 劉忠軍,黨耕町,馬慶軍,等.脊柱腫瘤的全脊椎切除術(shù)及脊柱穩(wěn)定性重建[J].中華骨科雜志,2001,21(11):646-649..
  8. 8. Vrionis FD,Small J.Surgical management of metastatic spinal neoplasms[J].Neurosurg Focus,2003,15(5):E12..
  9. 9. Tomita K,Kawahara N,Kobayashi T,et al.Surgical strategy for spinal metastases[J].Spine,2001,26:298-306..
  10. 10. Boriani S,Biagini R,De Iure F,et al.En bloc resections of bone tumors of the thoracolumbar spine.A preliminary report on 29 patients[J].Spine,1996,21(16):1927-1931.