目的:調(diào)查6個短串聯(lián)重復(fù)(short tandem repeat,STR)基因座在中國四川成都漢族人群中的基因頻率分布。方法:應(yīng)用四色熒光標記引物復(fù)合擴增技術(shù)對260名成都漢族無關(guān)個體的血樣6個STR基因座進行多態(tài)性研究。結(jié)果:在四川成都漢族人群中6個STR基因座個體識別機率PD為0.796~0.913,雜合度HO為0.627~0.796,多態(tài)信息含量PIC為0.57~0.75。6個STR基因座PD總值為0.999 995 97。所有基因座經(jīng)卡方檢驗符合Hard-Weinberg平衡。結(jié)論:上述6個STR基因座在成都漢族人群中等位基因分布較好,個體識別率高,適合法醫(yī)個體識別和親子鑒定。
引用本文: 美朗曲措,應(yīng)斌武,范紅. 6個STR基因座在四川成都漢族人群多態(tài)性分布. 華西醫(yī)學(xué), 2009, 24(1): 143-145. doi: 復(fù)制
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