目的：本研究旨在比較一種新的腦電參數(shù)-腦電非線性指數(shù)（ENI）與BIS在丙泊酚靶控輸注時預(yù)測鎮(zhèn)靜深度的能力。方法:選擇30例18～60歲，ASA Ⅰ～Ⅱ級，擬行擇期普外科手術(shù)患者。每一患者同時監(jiān)測ENI和BIS。麻醉誘導(dǎo)給予丙泊酚靶控輸注，直至患者意識消失后給予芬太尼和羅庫溴銨行氣管插管。麻醉誘導(dǎo)過程中每30秒進行一次鎮(zhèn)靜評分（采用改良OAA/S評分），并記錄ENI和BIS值以及平均動脈壓（MAP）和心率（HR）。結(jié)果:ENI和BIS與鎮(zhèn)靜評分的相關(guān)性比MAP和HR高（r=0.90、0.93 vs r=0.77、0.27）。鎮(zhèn)靜過程（改良OAA/S評分）中ENI和BIS有很好的相關(guān)性(R2=0.828)。ENI和BIS預(yù)測鎮(zhèn)靜深度的能力優(yōu)于MAP和HR。結(jié)論：ENI可提供與BIS相似的反映鎮(zhèn)靜深度的信息，能準確預(yù)測不同的鎮(zhèn)靜深度。
引用本文： 余海,楊小蕓,李茜,杜潤滋,銀燕,劉斌. 比較腦電非線性指數(shù)與BIS在丙泊酚靶控輸注時預(yù)測鎮(zhèn)靜深度的臨床研究. 華西醫(yī)學(xué), 2008, 23(1): 25-26. doi: 復(fù)制
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| 7. | Sleigh JW,Donovan J.Comparison of BIS,95 spectral edge frequency and approximate entropy of EEG,with change in heart variability during induction of general anaesthesia[J].Br J Anaesth,1999,82:666-71. |
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- 1. Smith WD,Dutton RC,Smith NT.Measuring the performance of anesthetic depth indicators[J].Anesthesiology,1996,84:38-51.
- 2. Gan TJ,Glass PS,Windsor A,et al.Bispectral index monitoring allows faster emergence and improved recovery from propofol,alfentanil,and nitrous oxide anesthesia[J].Anesthesiology,1997,87:808-15.
- 3. Struys MM,Jensen EW,Smith W,et al.Performance of the ARX-derived auditory evoked potential index as an indicator of anesthetic depth:A comparison with bispectral index andhemodynamic measures during propofol administration[J].Anesthesiology,2002,96:803-16.
- 4. Chernik DA,Gillings D,Laine H,et al.Validity and reliability of the observer’s assessment of alertness/sedation scale:study with intravenous midazolam[J].J Clin Psychopharmacol 1990,10:244-5.[5]Liu J,Harbhej S,White PF.Electroencephalographic bispectral index correlates with intraoperative recall and depth of propofol-induced sedation[J].Anesth Analg,1997,84:185-9.
- 5. Bauerle K,Greim CA,Schroth M,et al.Prediction of depth of sedation and anesthesia by the NarcotrendＴＭ EEG monitor[J].Br J Anaesth,2004,92:841-5.
- 6. Drummond JC.Mornitoring depth of anesthesia:With emphasis on the application of the Bispectral Index and the middle latency auditory evoked response to the prevention of recal.Anesthesiology,2000,93:876-82.
- 7. Sleigh JW,Donovan J.Comparison of BIS,95 spectral edge frequency and approximate entropy of EEG,with change in heart variability during induction of general anaesthesia[J].Br J Anaesth,1999,82:666-71.
- 8. Bruhn J,Bouillon TW,Shafer SL.Onset of propofol-induced burst suppression may be correctly detected as deepening of anesthesia by approximate entropy but not by bispectral index[J].Br J Anaesth,2001,87:505-7.