• 四川大學(xué)華西醫(yī)院 1腎內(nèi)科;2皮膚科，四川成都 610041;

目的：探討銀屑病合并蛋白尿患者的臨床特點(diǎn)。方法：回顧性分析1996年1月～2005年8月收治的銀屑病合并蛋白尿者臨床資料，并與銀屑病非蛋白尿者的臨床特點(diǎn)比較。結(jié)果：銀屑病合并不明原因蛋白尿48例，皮膚受累面積與蛋白尿程度無相關(guān)關(guān)系（P＞0.05），但銀屑病合并蛋白尿組的銀屑病病程更短,腎臟病理熒光表現(xiàn)為IgA沉積為主。蛋白尿組皮膚受累面積與非蛋白尿組皮膚受累面積比較，無統(tǒng)計(jì)學(xué)意義（P＞0.05），蛋白尿組和非蛋白尿組的病程也無統(tǒng)計(jì)學(xué)差異（P＞0.05）。結(jié)論：銀屑病合并不明原因蛋白尿值得重視，有必要對(duì)其發(fā)病機(jī)制、臨床特點(diǎn)、病理特征進(jìn)行深入的研究。

引用本文： 鐘慧,馬愛景,蔣獻(xiàn). 銀屑病合并蛋白尿48例臨床分析. 華西醫(yī)學(xué), 2008, 23(1): 117-118. doi: 復(fù)制

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2. Madeddu P，Ena P,Glorioso N,et al.High prevalence of microproteinuria,an early index of renal impairment,in patients withdiffuse psoriasis[J].Nephron，1988,48(3):222-225．.
3. Alenius GM,Stegmayr BG,Dahlqvist SR.Renalabnormalities in a population of patients with psoriatic arthritis[J].Scand JRheumatol，2001,30(5):271-4．.
4. Szepietowski JC,Bielicka E,Wasik F,et al.Microalbuminuria as a subclinical marker of renal in subjects with psoriasis vulgaris[J].J Eur Acad Dermatol Venereol，2000,14(6):513-514．.
5. Yamamoto M,Yorioka T,et al.A Case of IgA nephropathy associated with psoriasis vulgaris[J].Nippon Jinzo Gakkai Shi，1994,36(6):779-783．.
6. Tejinder S,Marjorie F,John J，et al.IgA nephropathy in psoriasis[J].Am J Nephrol，1998,18:425-429．.
7. 陳惠萍，王文榮，等．銀屑病所致的腎損害[J].腎臟病與透析移植雜志，2003,12(4):393-396．.
8. Yamaji H，Shikata K,Wada J,et al.A case of membranous nephropathy associated with psoriasis vulgaris[J].Acta Derm Venereol，1996,76(6):492．.
9. Kida H,Asamoto T,Abe T,et al.Psoriasis vulgaris associated with mesangiocapillary glomerulonephritis[J].Clin Nephrol，1985,23(50）：255-257．.
10. Saxena S,Verma K,Bhuyan UN,et al.Amyloidosis complicating psoriatic arthropathy[J].J Assoc Physicians India，1992,40(9):609-610．.
11. Hall RP,Peck GL,Lawley TJ.Circulating IgA immune complexes in patients with psoriasis[J].J Invest Dermatol，1983,80(6):465-468．.
12. 楊劍輝，井艷華，張紀(jì)蕓.銀屑病患者腎臟損害的臨床與病理觀察[J].中華皮膚科雜志，2002，35（2）:155．.
13. 于厚南,梅長(zhǎng)林，廖萬清.銀屑病并發(fā)慢性腎功能衰竭8例報(bào)道[J].腎臟病與透析腎移植雜志，1997,6(3)：242-243．.
  1. 1. [１]Omdal R，Husby G．Renal affection in patients with ankylosing sponylitis and psoriatic arthritis[J]．Clin Rheumatol，1987,6(1):74-79．.
  2. 2. Madeddu P，Ena P,Glorioso N,et al.High prevalence of microproteinuria,an early index of renal impairment,in patients withdiffuse psoriasis[J].Nephron，1988,48(3):222-225．.
  3. 3. Alenius GM,Stegmayr BG,Dahlqvist SR.Renalabnormalities in a population of patients with psoriatic arthritis[J].Scand JRheumatol，2001,30(5):271-4．.
  4. 4. Szepietowski JC,Bielicka E,Wasik F,et al.Microalbuminuria as a subclinical marker of renal in subjects with psoriasis vulgaris[J].J Eur Acad Dermatol Venereol，2000,14(6):513-514．.
  5. 5. Yamamoto M,Yorioka T,et al.A Case of IgA nephropathy associated with psoriasis vulgaris[J].Nippon Jinzo Gakkai Shi，1994,36(6):779-783．.
  6. 6. Tejinder S,Marjorie F,John J，et al.IgA nephropathy in psoriasis[J].Am J Nephrol，1998,18:425-429．.
  7. 7. 陳惠萍，王文榮，等．銀屑病所致的腎損害[J].腎臟病與透析移植雜志，2003,12(4):393-396．.
  8. 8. Yamaji H，Shikata K,Wada J,et al.A case of membranous nephropathy associated with psoriasis vulgaris[J].Acta Derm Venereol，1996,76(6):492．.
  9. 9. Kida H,Asamoto T,Abe T,et al.Psoriasis vulgaris associated with mesangiocapillary glomerulonephritis[J].Clin Nephrol，1985,23(50）：255-257．.
  10. 10. Saxena S,Verma K,Bhuyan UN,et al.Amyloidosis complicating psoriatic arthropathy[J].J Assoc Physicians India，1992,40(9):609-610．.
  11. 11. Hall RP,Peck GL,Lawley TJ.Circulating IgA immune complexes in patients with psoriasis[J].J Invest Dermatol，1983,80(6):465-468．.
  12. 12. 楊劍輝，井艷華，張紀(jì)蕓.銀屑病患者腎臟損害的臨床與病理觀察[J].中華皮膚科雜志，2002，35（2）:155．.
  13. 13. 于厚南,梅長(zhǎng)林，廖萬清.銀屑病并發(fā)慢性腎功能衰竭8例報(bào)道[J].腎臟病與透析腎移植雜志，1997,6(3)：242-243．.