• 江蘇省南通市第三人民醫(yī)院肝膽外科(江蘇南通 226000);

目的  探討白試驗在肝切除手術中檢測漏膽的價值。
方法  筆者所在醫(yī)院2008年1月至2013年1月期間在肝切除手術中采用白試驗聯(lián)合干紗布擦拭法檢測漏膽56例。即在肝切除手術操作末期,用干紗布擦拭法確認無漏膽后,經(jīng)膽囊管或左右肝管插管注入5%無菌脂肪乳劑10~30mL,同時用手阻斷遠端膽總管。觀察肝切除手術創(chuàng)面的白色液體滲出情況,對滲出白色液體處予以間斷縫合。重復操作,至斷面無白色液體滲出為止。
結果  56例患者經(jīng)術中檢測,發(fā)現(xiàn)漏膽17例(漏膽檢出率為30.4%),每例發(fā)現(xiàn)漏膽1~6處(平均2.9處),術中均予以確切縫合以關閉漏膽處,且重復試驗操作,證實均再無漏膽。術后發(fā)生漏膽2例(3.6%),經(jīng)相應治療后痊愈出院。全部患者出院后均隨訪3~6個月(平均3.8個月),無膈下積液或膈下感染病例發(fā)生。
結論  術中白試驗能夠發(fā)現(xiàn)漏膽的精確部位,不會污染肝切除手術創(chuàng)面,并能夠無限次地重復試驗,值得臨床推廣。

引用本文: 王建新,蔡衛(wèi)華,肖旭,王衛(wèi)兵,陳駿,蔡邢峰. 術中白試驗在肝切除術中肝斷面漏膽檢測中的應用. 中國普外基礎與臨床雜志, 2013, 20(12): 1407-1409. doi: 復制

1. 樊嘉, 王曉穎. 肝切除術后膽漏的處理[J]. 肝膽外科雜志, 2006, 14(4):243-244.
2. Nadalin S, Li J, Lang H, et al. The white test:a new dye test for intraoperative detection of bile leakage during major liver rese-ction[J]. Arch Surg, 2008, 143(4):402-404.
3. Shimada M, Takenaka K, Fujiwara Y, et al. Risk factors linked to postoperative morbidity in patients with hepatocellular carcinoma[J]. Br J Surg, 1998, 85(2):195-198.
4. Nagano Y, Togo S, Tanaka K, et al. Risk factors and managementof bile leakage after hepatic resection[J]. World J Surg, 2003, 27(6):695-698.
5. Ijichi M, Takayama T, Toyoda H, et al. Randomized trial of the usefulness of a bile leakage test during hepatic resection[J]. Arch Surg, 2000, 135(12):1395-1400.
6. Erdogan D, Busch OR, van Delden OM, et al. Incidence and management of bile leakage after partial liver resection[J]. Dig Surg, 2008, 25(1):60-66.
7. Capussotti L, Ferrero A, Viganò L, et al. Bile leakage and liver resection:where is the risk?[J]. Arch Surg, 2006, 141(7):690-694.
8. 董家鴻, 黃志強. 精準肝切除——21世紀肝臟外科新理念[J]. 中華外科雜志, 2009, 47(21):1601-1605.
9. 匡銘, 湯地, 王曄, 等. 三維手術模擬系統(tǒng)在肝癌患者精準肝切除中的應用[J]. 中國普外基礎與臨床雜志, 2011, 18(7):682-687.
10. Lang H, Radtke A, Liu C, et al. Extended left hepatectomy—modified operation planning based on three-dimensional visuali-zation of liver anatomy[J]. Langenbecks Arch Surg, 2004, 389 (4):306-310.
11. Taketomi A, Kitagawa D, Itoh S, et al. Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma:an institute’s experience with 625 patients[J]. J Am Coll Surg, 2007, 204(4):580-587.
12. Boonstra EA, de Boer MT, Sieders E, et al. Risk factors for central bile duct injury complicating partial liver resection[J]. Br J Surg, 2012, 99(2):256-262.
13. 樊嘉, 黃成. 原發(fā)性肝癌外科治療的進展[J]. 中國普外基礎與臨床雜志, 2009, 16(4):257-260.
14. 董家鴻, 冷建軍. 肝切除斷面處理[J]. 肝膽外科雜志, 2008, 16(2):95-96.
15. Tanaka S, Hirohashi K, Tanaka H, et al. Incidence and management of bile leakage after hepatic resection for malignant hepatic tumors[J]. J Am Coll Surg, 2002, 195(4):484-489.
  1. 1. 樊嘉, 王曉穎. 肝切除術后膽漏的處理[J]. 肝膽外科雜志, 2006, 14(4):243-244.
  2. 2. Nadalin S, Li J, Lang H, et al. The white test:a new dye test for intraoperative detection of bile leakage during major liver rese-ction[J]. Arch Surg, 2008, 143(4):402-404.
  3. 3. Shimada M, Takenaka K, Fujiwara Y, et al. Risk factors linked to postoperative morbidity in patients with hepatocellular carcinoma[J]. Br J Surg, 1998, 85(2):195-198.
  4. 4. Nagano Y, Togo S, Tanaka K, et al. Risk factors and managementof bile leakage after hepatic resection[J]. World J Surg, 2003, 27(6):695-698.
  5. 5. Ijichi M, Takayama T, Toyoda H, et al. Randomized trial of the usefulness of a bile leakage test during hepatic resection[J]. Arch Surg, 2000, 135(12):1395-1400.
  6. 6. Erdogan D, Busch OR, van Delden OM, et al. Incidence and management of bile leakage after partial liver resection[J]. Dig Surg, 2008, 25(1):60-66.
  7. 7. Capussotti L, Ferrero A, Viganò L, et al. Bile leakage and liver resection:where is the risk?[J]. Arch Surg, 2006, 141(7):690-694.
  8. 8. 董家鴻, 黃志強. 精準肝切除——21世紀肝臟外科新理念[J]. 中華外科雜志, 2009, 47(21):1601-1605.
  9. 9. 匡銘, 湯地, 王曄, 等. 三維手術模擬系統(tǒng)在肝癌患者精準肝切除中的應用[J]. 中國普外基礎與臨床雜志, 2011, 18(7):682-687.
  10. 10. Lang H, Radtke A, Liu C, et al. Extended left hepatectomy—modified operation planning based on three-dimensional visuali-zation of liver anatomy[J]. Langenbecks Arch Surg, 2004, 389 (4):306-310.
  11. 11. Taketomi A, Kitagawa D, Itoh S, et al. Trends in morbidity and mortality after hepatic resection for hepatocellular carcinoma:an institute’s experience with 625 patients[J]. J Am Coll Surg, 2007, 204(4):580-587.
  12. 12. Boonstra EA, de Boer MT, Sieders E, et al. Risk factors for central bile duct injury complicating partial liver resection[J]. Br J Surg, 2012, 99(2):256-262.
  13. 13. 樊嘉, 黃成. 原發(fā)性肝癌外科治療的進展[J]. 中國普外基礎與臨床雜志, 2009, 16(4):257-260.
  14. 14. 董家鴻, 冷建軍. 肝切除斷面處理[J]. 肝膽外科雜志, 2008, 16(2):95-96.
  15. 15. Tanaka S, Hirohashi K, Tanaka H, et al. Incidence and management of bile leakage after hepatic resection for malignant hepatic tumors[J]. J Am Coll Surg, 2002, 195(4):484-489.