目的 探討男性肝細胞癌患者的臨床病理特征、術(shù)后生存及預(yù)后影響因素。
方法 回顧性分析1995年1月至2002年12月期間我科行肝切除術(shù)之155例男性肝細胞癌患者的臨床及隨訪資料，單、多因素分析確定預(yù)后影響因素。
結(jié)果 與同期24例女性患者比較，男性肝細胞癌患者年長5.7歲，并有較高的HBsAg陽性率(80.6% vs 54.2%)和肝硬變比率（87.1% vs 37.5%)，P＜0.05,其他臨床病理指標差異無統(tǒng)計學(xué)意義（P＞0.05）。多因素分析提示，EdmondsonSteiner分級和門靜脈癌栓為男性患者術(shù)后總體生存和無瘤生存的獨立影響因素,衛(wèi)星灶和腫瘤大小僅影響總體生存。
結(jié)論 男性肝細胞癌患者主要的臨床病理特征及術(shù)后生存情況與女性患者相似。腫瘤分化程度和生物學(xué)行為是影響男性肝細胞癌患者術(shù)后生存的主要因素。
引用本文： 周立,芮靜安,王少斌,陳曙光,曲強,遲天毅,魏學(xué),韓凱,張寧,趙海濤. 男性肝細胞癌患者的臨床病理特點及影響因素. 中國普外基礎(chǔ)與臨床雜志, 2007, 14(1): 42-45. doi: 復(fù)制
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- 3. Lee CC, Chau GY, Lui WY, et al. Better post-resectional survival in female cirrhotic patients with hepatocellular carcinoma [Ｊ]. Hepatogastroenterology， 2000; 47(32)∶446.
- 4. Tangkijvanich P, Mahachai V, Suwangool P, et al. Gender di-fference in clinicopathologic features and survival of patients with hepatocellular carcinoma [Ｊ]. World J Gastroenterol， 2004; 10(11)∶1547.
- 5. Tsai TJ, Chau GY, Lui WY, et al. Clinical significance of microscopic tumor venous invasion in patients with resectable hepatocellular carcinoma [Ｊ]. Surgery， 2000; 127(6)∶603.
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