目的 探討原發(fā)性甲狀旁腺功能亢進(jìn)癥(PHPT)的診治經(jīng)驗(yàn)。
方法 回顧性分析我院近15年間18例手術(shù)治療的PHPT患者的臨床資料。
結(jié)果 初診病例術(shù)前核素99Tcm-sestamibi掃描和B超檢查陽(yáng)性定位診斷率分別為100%（9/9）和88%（15/17）。18例均經(jīng)手術(shù)治療，其中1例為再手術(shù)病例。術(shù)后病理診斷甲狀旁腺腺瘤13例，其中1例為雙腺瘤； 甲狀旁腺增生4例； 甲狀旁腺腺癌1例。首次手術(shù)治愈率為88%（15/17）。2例甲狀旁腺增生病例未治愈。再手術(shù)1例因損傷了單側(cè)喉返神經(jīng)致術(shù)后聲音嘶啞。
結(jié)論 術(shù)前核素99Tcm-sestamibi掃描和B超檢查對(duì)制定手術(shù)方案有重要意義，大多數(shù)PHPT病例適合行單側(cè)頸部探查術(shù)。甲狀旁腺增生病例的手術(shù)治愈率低。
引用本文： 解乃昌,林進(jìn)令,陸云飛. 18例原發(fā)性甲狀旁腺功能亢進(jìn)癥的診治分析. 中國(guó)普外基礎(chǔ)與臨床雜志, 2007, 14(1): 87-88. doi: 復(fù)制
| 1. | AACE/AAES Task Force on Primary Hyperparathyroidism. The American Association of Clinical Endocrinologists and the American Association of Endocrine Surgeons position statement on the diagnosis and management of primary hyperparathyroidism [Ｊ]. Endocr Pract, 2005; 11(1)∶49. |
| 2. | Inabnet WB. Intraoperative parathyroid hormone monitoring [Ｊ]. World J Surg, 2004; 28(12)∶1212. |
| 3. | Parikshak M, Castillo ED, Conrad MF, et al. Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for priary hyperparathyroidism [Ｊ]. Am Surg, 2003; 69(5)∶393. |
- 1. AACE/AAES Task Force on Primary Hyperparathyroidism. The American Association of Clinical Endocrinologists and the American Association of Endocrine Surgeons position statement on the diagnosis and management of primary hyperparathyroidism [Ｊ]. Endocr Pract, 2005; 11(1)∶49.
- 2. Inabnet WB. Intraoperative parathyroid hormone monitoring [Ｊ]. World J Surg, 2004; 28(12)∶1212.
- 3. Parikshak M, Castillo ED, Conrad MF, et al. Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for priary hyperparathyroidism [Ｊ]. Am Surg, 2003; 69(5)∶393.