• 溫州醫(yī)學(xué)院附屬第六醫(yī)院麗水市人民醫(yī)院普外科(浙江麗水323000);

目的  探討乳腺葉狀囊肉瘤和巨纖維腺瘤的診斷和治療。
方法  回顧分析我院1985~2002年期間外科收治的9例乳腺葉狀囊肉瘤和8例乳腺巨纖維腺瘤的臨床資料。
結(jié)果  9例乳腺葉狀囊肉瘤中行單純?nèi)榉壳谐g(shù)4例,保留乳頭皮下乳房切除術(shù)1例,保留乳頭和部分壓縮腺體+腫塊切除術(shù)1例,改良根治術(shù)3例; 術(shù)后恢復(fù)良好,僅1例復(fù)發(fā)。8例乳腺巨纖維腺瘤中行單純?nèi)榉壳谐g(shù)2例,保留乳頭皮下乳房切除術(shù)1例,保留乳頭和部分壓縮腺體+腫塊切除術(shù)2例,單純?nèi)橄倌[塊切除術(shù)3例; 術(shù)后恢復(fù)良好,術(shù)后2例復(fù)發(fā)。
結(jié)論  乳腺葉狀囊肉瘤和巨纖維腺瘤臨床上均表現(xiàn)為無痛性包塊,除乳腺葉狀囊肉瘤發(fā)病年齡較大、腫塊范圍大及易惡變外,二者主要依據(jù)病理檢查結(jié)果相鑒別; 均以手術(shù)治療為主,根據(jù)患者年齡、腫塊大小以及病理檢查結(jié)果選擇不同的手術(shù)方式。

引用本文: 施勇. 乳腺葉狀囊肉瘤和巨纖維腺瘤診治體會(附17例報告). 中國普外基礎(chǔ)與臨床雜志, 2007, 14(1): 92-93. doi: 復(fù)制

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2.  Dacic S, Kounelis S, Kouri E, et al. Immunohistochemical profile of cystosarcoma phyllodes of the breast: a study of 23 cases [J]. Breast J, 2002; 8(6)∶376.
3.  楊名添, 劉廣森. 乳腺巨纖維腺瘤和葉狀囊肉瘤的臨床診斷與治療——52例分析 [J]. 中山醫(yī)科大學(xué)學(xué)報, 1987; 8(3)∶69.
4.  Chao TC, Lo YF, Chen SC, et al. Sonographic features of phyllodes tumors of the breast [J]. Ultrasound Obstet Gynecol, 2002; 20(1)∶64.
5.  Kapiris I, Nasiri N, A’Hern R, et al. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast [J]. Eur J Surg Oncol, 2001; 27(8)∶723.
6.  Khan SA, Badve S. Phyllodes tumors of the breast [J]. Curr Treat Options Oncol, 2001; 2(2)∶139.
7.  Ridgway PF, Jacklin RK, Ziprin P, et al. Perioperative diagnosis of cystosarcoma phyllodes of the breast may be enhanced by MIB-1 index [J]. J Surg Res, 2004; 122(1)∶83.
8.  Kok KY, Telesinghe PU, Yapp SK. Treatment and outcome of cystosarcoma phyllodes in Brunei: a 13-year experience [J]. J R Coll Surg Edinb, 2001; 46(4)∶198.
9.  Zahner J, Bassler R. The rate of mitosis in cystosarcoma phyllodes (phyllodes tumor, WHO) of the breast. An analysis of 47 cases [J]. Arch Gynecol Obstet, 1989; 246(3)∶153.
10.  Pandey M, Mathew A, Kattoor J, et al. Malignant phyllodes tumor [J]. Breast J, 2001; 7(6)∶411.
11.  Daya M, Mahomva O, Madaree A, et al. Reduction mammoplasty in cases of giant fibroadenoma among adolescent females. Case reports and literature review [J]. S Afr J Surg, 2003; 41(2)∶39.
  1. 1.  Salvadori B, Cusumano F, Del Bo R, et al. Surgical treatment of phyllodes tumors of the breast [J]. Cancer, 1989; 63(12)∶2532.
  2. 2.  Dacic S, Kounelis S, Kouri E, et al. Immunohistochemical profile of cystosarcoma phyllodes of the breast: a study of 23 cases [J]. Breast J, 2002; 8(6)∶376.
  3. 3.  楊名添, 劉廣森. 乳腺巨纖維腺瘤和葉狀囊肉瘤的臨床診斷與治療——52例分析 [J]. 中山醫(yī)科大學(xué)學(xué)報, 1987; 8(3)∶69.
  4. 4.  Chao TC, Lo YF, Chen SC, et al. Sonographic features of phyllodes tumors of the breast [J]. Ultrasound Obstet Gynecol, 2002; 20(1)∶64.
  5. 5.  Kapiris I, Nasiri N, A’Hern R, et al. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast [J]. Eur J Surg Oncol, 2001; 27(8)∶723.
  6. 6.  Khan SA, Badve S. Phyllodes tumors of the breast [J]. Curr Treat Options Oncol, 2001; 2(2)∶139.
  7. 7.  Ridgway PF, Jacklin RK, Ziprin P, et al. Perioperative diagnosis of cystosarcoma phyllodes of the breast may be enhanced by MIB-1 index [J]. J Surg Res, 2004; 122(1)∶83.
  8. 8.  Kok KY, Telesinghe PU, Yapp SK. Treatment and outcome of cystosarcoma phyllodes in Brunei: a 13-year experience [J]. J R Coll Surg Edinb, 2001; 46(4)∶198.
  9. 9.  Zahner J, Bassler R. The rate of mitosis in cystosarcoma phyllodes (phyllodes tumor, WHO) of the breast. An analysis of 47 cases [J]. Arch Gynecol Obstet, 1989; 246(3)∶153.
  10. 10.  Pandey M, Mathew A, Kattoor J, et al. Malignant phyllodes tumor [J]. Breast J, 2001; 7(6)∶411.
  11. 11.  Daya M, Mahomva O, Madaree A, et al. Reduction mammoplasty in cases of giant fibroadenoma among adolescent females. Case reports and literature review [J]. S Afr J Surg, 2003; 41(2)∶39.