• 四川大學(xué)華西醫(yī)院放射科（成都610041）;

目的  對(duì)比分析菲立磁增強(qiáng)掃描與螺旋CT增強(qiáng)掃描對(duì)局灶性肝病的定性診斷價(jià)值。
方法  收集經(jīng)本院完成螺旋CT增強(qiáng)掃描及菲立磁增強(qiáng)MRI掃描且臨床、手術(shù)病理證實(shí)為局灶性肝病者26例57個(gè)病灶，采用分組盲法受試者操作特性（ROC）曲線分析對(duì)比評(píng)價(jià)菲立磁增強(qiáng)MRI與螺旋CT增強(qiáng)掃描對(duì)局灶性肝病的定性診斷價(jià)值。
結(jié)果  平掃+菲立磁增強(qiáng)MRI組ROC曲線下面積（Az值）最大，為0.926 0，準(zhǔn)確性為86.8%，差異有顯著性意義（P＜0.05）。螺旋CT增強(qiáng)掃描、MRI平掃及單獨(dú)分析菲立磁增強(qiáng)MRI 3種方法之間差異無顯著性意義（P gt;0.05）。
結(jié)論  菲立磁增強(qiáng)MRI對(duì)肝局灶性病變的定性診斷價(jià)值高于螺旋CT增強(qiáng)掃描。聯(lián)合分析平掃+菲立磁增強(qiáng)MRI較單獨(dú)分析菲立磁增強(qiáng)能明顯改善病灶的定性診斷能力。

引用本文： 楊漢豐,宋彬,周翔平,余建群,陳衛(wèi)霞,陳憲,孫家瑜,陳茀茀,朱紅梅. 菲立磁增強(qiáng)MRI對(duì)局灶性肝病的定性診斷價(jià)值. 中國(guó)普外基礎(chǔ)與臨床雜志, 2004, 11(5): 454-457下轉(zhuǎn)465. doi: 復(fù)制

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2. Soyer P. Will ferumoxidesenhanced MR imaging replace CT during arterial portography in the detection of hepatic metastases? Prologue to a promising future [Ｊ]. Radiology, 1996; 200(3)∶600.
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7. Nakayama M, Yamashita Y, Mitsuzaki K, et al. Improved tissue characterization of focal liver lesions with ferumoxideenhanced T1 and T2weighted MR imaging [Ｊ]. J Magn Reson Imaging, 2000; 11(6)∶647.
8. Grangier C, Tourniaire J, Mentha G, et al. Enhancement of liver hemangiomas on T1weighted MR SE images by superparamagnetic iron oxide particles [Ｊ]. J Comput Assist Tomogr, 1994; 18(6)∶888.
9. Sahani D, Saini S, Sharma R, et al. Dynamic T1weighted ferumoxides enhanced MRI for imaging liver hemangiomas: preliminary observations [Ｊ]. Abdom Imaging, 2001; 26(2)∶166.
10. 劉劍羽，謝敬霞，姚學(xué)會(huì)，等. 菲立磁增強(qiáng)MRI在肝臟局灶性病變的診斷價(jià)值 [Ｊ]. 臨床放射學(xué)雜志， 2001； 20（4）∶256.
11. Oudkerk M, van den Heuvel AG, Wielopolski PA, et al. Hepatic lesions: detection with ferumoxideenhanced T1weighted MR imaging [Ｊ]. Radiology, 1997; 203(2)∶449.
  1. 1. Seneterre E, Taourel P, Bouvier Y, et al. Detection of hepatic metastases: ferumoxidesenhanced MR imaging versus unenhanced MR imaging and CT during arterial portography [Ｊ]. Radiology, 1996; 200(3)∶785.
  2. 2. Soyer P. Will ferumoxidesenhanced MR imaging replace CT during arterial portography in the detection of hepatic metastases? Prologue to a promising future [Ｊ]. Radiology, 1996; 200(3)∶600.
  3. 3. Vogl TJ, Hammerstingl R, Schwarz W, et al. Superparamagnetic iron oxide——enhanced versus gadoliniumenhanced MR imaging for differential diagnosis of focal liver lesions [Ｊ]. Radiology, 1996; 198(3)∶881.
  4. 4. Ishida T, Murakami T, Kato N, et al. Superparamagnetic iron oxide enhanced magnetic resonance imaging of rat liver with hepatocellular carcinoma and benign hyperplastic nodule [Ｊ]. Invest Radiol, 1997; 32(5)∶282.
  5. 5. Grandin C, Van Beers BE, Robert A, et al. Benign hepatocellular tumors: MRI after superparamagnetic iron oxide administration [Ｊ]. J Comput Assist Tomogr, 1995; 19(3)∶412.
  6. 6. Paley MR, Mergo PJ, Torres GM, et al. Characterization of focal hepatic lesions with ferumoxidesenhanced T2weighted MR imaging [Ｊ]. AJR Am J Roentgenol, 2000; 175(1)∶159.
  7. 7. Nakayama M, Yamashita Y, Mitsuzaki K, et al. Improved tissue characterization of focal liver lesions with ferumoxideenhanced T1 and T2weighted MR imaging [Ｊ]. J Magn Reson Imaging, 2000; 11(6)∶647.
  8. 8. Grangier C, Tourniaire J, Mentha G, et al. Enhancement of liver hemangiomas on T1weighted MR SE images by superparamagnetic iron oxide particles [Ｊ]. J Comput Assist Tomogr, 1994; 18(6)∶888.
  9. 9. Sahani D, Saini S, Sharma R, et al. Dynamic T1weighted ferumoxides enhanced MRI for imaging liver hemangiomas: preliminary observations [Ｊ]. Abdom Imaging, 2001; 26(2)∶166.
  10. 10. 劉劍羽，謝敬霞，姚學(xué)會(huì)，等. 菲立磁增強(qiáng)MRI在肝臟局灶性病變的診斷價(jià)值 [Ｊ]. 臨床放射學(xué)雜志， 2001； 20（4）∶256.
  11. 11. Oudkerk M, van den Heuvel AG, Wielopolski PA, et al. Hepatic lesions: detection with ferumoxideenhanced T1weighted MR imaging [Ｊ]. Radiology, 1997; 203(2)∶449.