• 解放軍304醫(yī)院(北京100037);

在外科領(lǐng)域,預(yù)防性使用抗生素占有相當(dāng)重要的地位,這主要是為了預(yù)防外科手術(shù)部位感染,包括外科手術(shù)后的切口感染和手術(shù)部位的深部腔隙或器官感染,如胸腔感染、腹腔感染、膿腫形成等。此類感染約占醫(yī)院全部感染的14%~16%,占外科患者感染的38%[1],其重要性不容忽視。

引用本文: 黎沾良. 合理使用抗生素預(yù)防手術(shù)部位感染. 中國普外基礎(chǔ)與臨床雜志, 2003, 10(1): 14-15. doi: 復(fù)制

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2. Polk HC Jr, Christmas AB. Prophylactic antibiotics in surgery and surgical wound infections [J]. Am Surg, 2000; 66(2)∶105.
3. Haley RW, Culver DH, Morgan WM, et al. Identifying patients at high risk of surgical wound infection. A simple multivariate index of patient susceptibility and wound contamination [J]. Am J Epidemiol, 1985; 121(2)∶206.
4. Novelli A. Antimicrobial prophylaxis in surgery: the role of pharmacokinetics [J]. J Chemother, 1999; 11(6)∶565.
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6. Scher KS. Studies on the duration of antibiotic administration for surgical prophylaxis [J]. Am Surg, 1997; 63(1)∶59.
7. Fabian TC, Croce MA, Payne LW, et al. Duration of antibiotic therapy for penetrating abdominal trauma: a prospective trial [J].Surgery, 1992; 112(4)∶788.
  1. 1. Emori TG, Gaynes RP. An overview of nosocomial infections, including the role of the microbiology laboratory [J]. Clin Microbiol Rev, 1993; 6(4)∶428.
  2. 2. Polk HC Jr, Christmas AB. Prophylactic antibiotics in surgery and surgical wound infections [J]. Am Surg, 2000; 66(2)∶105.
  3. 3. Haley RW, Culver DH, Morgan WM, et al. Identifying patients at high risk of surgical wound infection. A simple multivariate index of patient susceptibility and wound contamination [J]. Am J Epidemiol, 1985; 121(2)∶206.
  4. 4. Novelli A. Antimicrobial prophylaxis in surgery: the role of pharmacokinetics [J]. J Chemother, 1999; 11(6)∶565.
  5. 5. Esposito S. Is singledose antibiotic prophylaxis sufficient for any surgical procedure? [J]. J Chemother, 1999; 11(6)∶556.
  6. 6. Scher KS. Studies on the duration of antibiotic administration for surgical prophylaxis [J]. Am Surg, 1997; 63(1)∶59.
  7. 7. Fabian TC, Croce MA, Payne LW, et al. Duration of antibiotic therapy for penetrating abdominal trauma: a prospective trial [J].Surgery, 1992; 112(4)∶788.