為了探討增加細胞內(nèi)糖原含量能否改善肝臟缺血再灌注損傷程度，本實驗對3組糖原含量顯著不同的兔肝臟缺血再灌注過程中的組織形態(tài)學、肝臟酶學、組織ATP含量、細胞膜Ca2+-ATP酶活性及胞漿內(nèi)游離Ca2+濃度進行了觀察。結(jié)果： 糖原含量高的肝臟，其細胞能量代謝旺盛，細胞膜Ca2+-ATP酶活性強，胞漿內(nèi)游離Ca2+濃度相對穩(wěn)定，組織結(jié)構(gòu)及功能損傷輕。本實驗結(jié)果提示： 缺血前增加肝臟糖原含量可顯著地拮抗肝臟缺血再灌注損傷。
引用本文： 湯禮軍,田伏洲,王雨,李曉軍,尹致良. 肝細胞糖原拮抗肝臟缺血再灌注損傷及其相關機理的研究. 中國普外基礎與臨床雜志, 1999, 6(4): 196-198. doi: 復制
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