• 西安醫(yī)科大學(xué)附屬第二醫(yī)院普外科(西安710004);

引用本文： 李漢臣,秦兆寅,紀宗正. 失血性休克免疫學(xué)研究進展. 中國普外基礎(chǔ)與臨床雜志, 1995, 2(4): 240-243. doi: 復(fù)制

版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《中國普外基礎(chǔ)與臨床雜志》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編

1. Esrig BC, Frazee L,Stephenson SF, et al. Predisposition to infection and neutrophil function fllowing hemorrhagic shock. Rew Surg,1976;33:413.
2. Stephan RN, Kupper TS, Gaha AS, et al. Hemorrhage without tissue trauma produces immunosuppression and enhances susceptibility to sepsis. Arch Surg, 1987; 122:312.
3. Livingston DH, Malangoni MA. An excerimental study of susceptibility to infection after hemorragic shock. Surg Gynecol Obstet, 1989; 168: 138.
4. Abrabam E, Chang YH. The effects of hemorrhage on mitogen-induced lymphocyte proliferation. Circ Shock, 1985; 15: 141.
5. Abraham E, Freitas AA. Hemorrhage Produces abnormalities in lymphocyte function and lymphokine generation. J Immunol, 1989; 142:899.
6. 李漢臣， 李 劍，金紹岐. 急性失血對大鼠外周血白細胞數(shù)量和分類的影響. 中華實驗外科雜志， 1992；9（增刊）：95.
7. Shatney CH, Read G, Cuevo R,et al. The natural leukocyte response to hemorrhagic shock. Adv Shock Res.1981; 5:79.
8. 李漢臣， 孫傳興， 金紹岐. 清醒兔失血性休克后外周血白細胞數(shù)量和分類的變化. 第四軍醫(yī)大學(xué)學(xué)報，1992；13：441.
9. Stephan RN,Ayala A,Harkema JM,et al. Mechanism of immunosuppression following hemorrhage: defective antigen presentation by macrohages. J Surg Res, 1989; 46: 533.
10. Ayala A, Perrin MM, Wagner MA,et al. Enhanced susceptibility to sepsis following simple hemorrhage: depression of Fc and C3b receptor-mediated phagocytosis. Arch Surg, 1990;125: 70.
11. Ayala A, Walsh MM, Chaudry IH. Defective macrophage antigen presentation following hemorrhage is associated with loss of MHCⅡ（Ia）antigens. Immunology,1990;70:33.
12. Ayala A, Perrin MM,Chautry IH.Increase susceptibility to sepsis following hemorrhage: defective kupffer cell-mediated antigen presentation. Surg Form, 1989; 40: 102.
13. Ayala A, Perrin MM, Ertel W,et al. Hemorrhage induced an increase in serum TNF which is not associated with eleveated leves of endotoxin. Cytokine,1990;2:170.
14. Cuddy BG, Loegering DJ, Blumenstock FA,et al.Heptic macrophage complement receptor clearance function following injury. J Surg Res. 1986; 40: 216.
15. Abraham E,Chang YH. Effects of hemorrhage on interleukin-1 producfion.Circ Shock,1988;25:33.
16. Meldrum Dr, Ayala A, Perrin MM,et al. Diltiazem retores lymphorines synthesis and decrease susceptibility to sepsis following hemorrhage. J Surg Res,1991;51: 158.
17. Stephan RN, Poo WJ,Janeway CA.Prolonged impairment of natural killer(NK) cell activity following simple hemorrhage. Circ Shock,1987; 21: 312.
18. Abraham E,Freitas AA,Coutinho AA. Hemorrhage in mice produce alteration in B-cell repertores. Cell Immunol,1980;122:208.
19. Abraham E, Freitas AA.Hemorrhage induced alteration in immunoglobulin-secreting B cells. Crit Care Med, 1989; 122: 208.
20. 李漢臣，孫傳興，金紹岐. 失血性休克家兔血漿IgG的變化.中華實驗外科雜志，1993；10：27.
21. Paty PB,Barda MJ,Hunt TK. Activation of microphages by L-lactic acid.Surg Form,1988;39:27.
22. Gillis S, Crabtree GR,Smith KA.Glucocoticoid induced inhibition of T-cell growth factor production: the effect on mitogen-induced lymphocyte proliferation. J Immunol,1979;123:1624.
23. Fertsch-Ruggio D,Schoenberg DR,Vogel SN,et al. Induction of macrophage Ia antigen expression by γ IFN-gamma and down-regulation by IFN-αlpha/beta and dexamethasone are regulated transcriptionally.J Immunol,1988;141:1582.
24. Crary B,Hauser SL,Borysenko M,et al. Epinephrine-induced Changes in the distribution of lymphocyte subsets in peripheral blood of hunmans.J Immunol,1983;131:1178.
25. Stephan RN,Janeway CA,Dean RE,et al. Prostaglandin E2 depress antigen presenting cell function of peritoneal macrophages,J Surg Res,1988;44:733.
26. Ertel W,Morrison MH,Meldrum DR,et al. Ibuprofen restores cellular immunity and decreases susceptibility to sepsis following hemorrhage. J Surg Res,1992;53:55.
27. Abraham E,Change YH. Generation of functionally active suppressor cells by hemorrhage and hemorrhagic serum. Cire Care Med,1991;19:613.
28. 李漢臣，孫傳興，金紹岐等. 家兔失血性休克后細胞免疫的變化. 中華實驗外科雜志，1992；9（增刊）：93.
29. Livingston DH,Malangoni MA.Interferon-gamma restores immune competence after hemorrhagic shock. J Sur Res,1988;45:37.
30. Ertel W,Morrison MH,Ayala A,et al.Interferon-γ（IFN-γ）administration in vivo following hemorrhagic shock restores macrophage(Mф）antigen presention and the processes associatied with it(abstract).Circ Shock,1990;31:30.
31. Livingston DH,Malangoni MA,Sonnenfeld G.Immune enhancement by tumor necrosis factor-alpha improves antibiotic efficiency after hemorrhagic shock.J Trauma,1989;29:967.
32. Ertel W,Meldrum D,Morrison M,et al.Immunoprotective effect of a calcium channel blocker on macrophage atigen presentation function Ia expression and interleukin-1 synthesis following hemorrhage.Surgery,1990;108:154.
33. Ertel W,Morrison MH,Ayala A,et al.Blockage of prostaglandin production increases cachection synthesis and prevents depression of macrophage functions after hemorrhagic shock.Ann Surg,1991;213:263.
  1. 1. Esrig BC, Frazee L,Stephenson SF, et al. Predisposition to infection and neutrophil function fllowing hemorrhagic shock. Rew Surg,1976;33:413.
  2. 2. Stephan RN, Kupper TS, Gaha AS, et al. Hemorrhage without tissue trauma produces immunosuppression and enhances susceptibility to sepsis. Arch Surg, 1987; 122:312.
  3. 3. Livingston DH, Malangoni MA. An excerimental study of susceptibility to infection after hemorragic shock. Surg Gynecol Obstet, 1989; 168: 138.
  4. 4. Abrabam E, Chang YH. The effects of hemorrhage on mitogen-induced lymphocyte proliferation. Circ Shock, 1985; 15: 141.
  5. 5. Abraham E, Freitas AA. Hemorrhage Produces abnormalities in lymphocyte function and lymphokine generation. J Immunol, 1989; 142:899.
  6. 6. 李漢臣， 李 劍，金紹岐. 急性失血對大鼠外周血白細胞數(shù)量和分類的影響. 中華實驗外科雜志， 1992；9（增刊）：95.
  7. 7. Shatney CH, Read G, Cuevo R,et al. The natural leukocyte response to hemorrhagic shock. Adv Shock Res.1981; 5:79.
  8. 8. 李漢臣， 孫傳興， 金紹岐. 清醒兔失血性休克后外周血白細胞數(shù)量和分類的變化. 第四軍醫(yī)大學(xué)學(xué)報，1992；13：441.
  9. 9. Stephan RN,Ayala A,Harkema JM,et al. Mechanism of immunosuppression following hemorrhage: defective antigen presentation by macrohages. J Surg Res, 1989; 46: 533.
  10. 10. Ayala A, Perrin MM, Wagner MA,et al. Enhanced susceptibility to sepsis following simple hemorrhage: depression of Fc and C3b receptor-mediated phagocytosis. Arch Surg, 1990;125: 70.
  11. 11. Ayala A, Walsh MM, Chaudry IH. Defective macrophage antigen presentation following hemorrhage is associated with loss of MHCⅡ（Ia）antigens. Immunology,1990;70:33.
  12. 12. Ayala A, Perrin MM,Chautry IH.Increase susceptibility to sepsis following hemorrhage: defective kupffer cell-mediated antigen presentation. Surg Form, 1989; 40: 102.
  13. 13. Ayala A, Perrin MM, Ertel W,et al. Hemorrhage induced an increase in serum TNF which is not associated with eleveated leves of endotoxin. Cytokine,1990;2:170.
  14. 14. Cuddy BG, Loegering DJ, Blumenstock FA,et al.Heptic macrophage complement receptor clearance function following injury. J Surg Res. 1986; 40: 216.
  15. 15. Abraham E,Chang YH. Effects of hemorrhage on interleukin-1 producfion.Circ Shock,1988;25:33.
  16. 16. Meldrum Dr, Ayala A, Perrin MM,et al. Diltiazem retores lymphorines synthesis and decrease susceptibility to sepsis following hemorrhage. J Surg Res,1991;51: 158.
  17. 17. Stephan RN, Poo WJ,Janeway CA.Prolonged impairment of natural killer(NK) cell activity following simple hemorrhage. Circ Shock,1987; 21: 312.
  18. 18. Abraham E,Freitas AA,Coutinho AA. Hemorrhage in mice produce alteration in B-cell repertores. Cell Immunol,1980;122:208.
  19. 19. Abraham E, Freitas AA.Hemorrhage induced alteration in immunoglobulin-secreting B cells. Crit Care Med, 1989; 122: 208.
  20. 20. 李漢臣，孫傳興，金紹岐. 失血性休克家兔血漿IgG的變化.中華實驗外科雜志，1993；10：27.
  21. 21. Paty PB,Barda MJ,Hunt TK. Activation of microphages by L-lactic acid.Surg Form,1988;39:27.
  22. 22. Gillis S, Crabtree GR,Smith KA.Glucocoticoid induced inhibition of T-cell growth factor production: the effect on mitogen-induced lymphocyte proliferation. J Immunol,1979;123:1624.
  23. 23. Fertsch-Ruggio D,Schoenberg DR,Vogel SN,et al. Induction of macrophage Ia antigen expression by γ IFN-gamma and down-regulation by IFN-αlpha/beta and dexamethasone are regulated transcriptionally.J Immunol,1988;141:1582.
  24. 24. Crary B,Hauser SL,Borysenko M,et al. Epinephrine-induced Changes in the distribution of lymphocyte subsets in peripheral blood of hunmans.J Immunol,1983;131:1178.
  25. 25. Stephan RN,Janeway CA,Dean RE,et al. Prostaglandin E2 depress antigen presenting cell function of peritoneal macrophages,J Surg Res,1988;44:733.
  26. 26. Ertel W,Morrison MH,Meldrum DR,et al. Ibuprofen restores cellular immunity and decreases susceptibility to sepsis following hemorrhage. J Surg Res,1992;53:55.
  27. 27. Abraham E,Change YH. Generation of functionally active suppressor cells by hemorrhage and hemorrhagic serum. Cire Care Med,1991;19:613.
  28. 28. 李漢臣，孫傳興，金紹岐等. 家兔失血性休克后細胞免疫的變化. 中華實驗外科雜志，1992；9（增刊）：93.
  29. 29. Livingston DH,Malangoni MA.Interferon-gamma restores immune competence after hemorrhagic shock. J Sur Res,1988;45:37.
  30. 30. Ertel W,Morrison MH,Ayala A,et al.Interferon-γ（IFN-γ）administration in vivo following hemorrhagic shock restores macrophage(Mф）antigen presention and the processes associatied with it(abstract).Circ Shock,1990;31:30.
  31. 31. Livingston DH,Malangoni MA,Sonnenfeld G.Immune enhancement by tumor necrosis factor-alpha improves antibiotic efficiency after hemorrhagic shock.J Trauma,1989;29:967.
  32. 32. Ertel W,Meldrum D,Morrison M,et al.Immunoprotective effect of a calcium channel blocker on macrophage atigen presentation function Ia expression and interleukin-1 synthesis following hemorrhage.Surgery,1990;108:154.
  33. 33. Ertel W,Morrison MH,Ayala A,et al.Blockage of prostaglandin production increases cachection synthesis and prevents depression of macrophage functions after hemorrhagic shock.Ann Surg,1991;213:263.