• 上海交通大學(xué)附屬第一人民醫(yī)院檢驗(yàn)科(上海 200080);

引用本文: 藺麗慧,李莉. 過(guò)敏性哮喘及其它過(guò)敏性疾病免疫生物治療研究進(jìn)展. 中國(guó)呼吸與危重監(jiān)護(hù)雜志, 2009, 09(3): 300-302. doi: 復(fù)制

版權(quán)信息: ?四川大學(xué)華西醫(yī)院華西期刊社《中國(guó)呼吸與危重監(jiān)護(hù)雜志》版權(quán)所有,未經(jīng)授權(quán)不得轉(zhuǎn)載、改編

1. Bousquet J,Dahl R,Khaltaev N.Global alliance against chronic respiratory diseases.Allergy,2007,62:216-223.
2. Holgate S,Casale T,Wenzel S,et al.The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation.J Allergy Clin Immunol,2005,115:459-465.
3. Bradding P,Walls AF,Holgate ST.The role of the mast cell in the pathophysiology of asthma.J Allergy Clin Immunol,2006,117:1277-1284.
4. Cruse G,Kaur D,Yang W,et al.Activation of human lung mast cells by monomeric immunoglobulin E.Eur Respir J,2005,25:858-863.
5. Slavin RG,F(xiàn)erioli C,Tannenbaum SJ,et al.Asthma symptom re-emergence after omalizumab withdrawal correlates well with increasing IgE and decreasing pharmacokinetic concentrations.J Allergy Clin Immunol,2009,123:107-113.
6. Lin H,Boesel KM,Griffith DT,et al.Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils.J Allergy Clin Immunol,2004,113:297-302.
7. Djukanovi? R,Wilson SJ,Kraft M,et al.Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma.Am J Respir Crit Care Med,2004,170:583-593.
8. Soler M.Anti-IgE antibodies in the treatment of allergic diseases.Allergol Immunol Clin,2002,42:45-49. 8 Hayashi N,Tsukamoto Y,Sallas WM,et al.A mechanism-based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab.Br J Clin Pharmacol,2007,63:548-561.
9. Dodig S,Richter D,Cepelak I.Anti-IgE therapy with omalizumab in asthma and allergic rhinitis.Acta Pharm,2005,55:123-138.
10. Saxon A,Kepley CL,Zhang K,et al."Accentuate the negative,eliminate the positive":engineering allergy therapeutics to block allergic reactivity through negative signaling.J Allergy Clin Immunol,2008,121:320-325.
11. Kepley CL,Taghavi S,Mackay G,et al.Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes.J Biol Chem,2004,279:35139-35149.
12. Daëron M,Malbec O,Latour S,et al.Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.J Clin Invest,1995,95:577-585.
13. Zhu D,Kepley CL,Zhang K,et al.A novel human immunoglobulin Fcγ–Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation.Nat med,2005,11:446-449.
14. Zhang K,Kepley CL,Terada T,et al.Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein.J Allergy Clin Immunol,2004,114:321-327.
15. Kepley CL,Zhang K,Zhu D,et al.Fc?RI-Fc?RII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells.Clin Immunol,2003,108:89-94.
16. Yamada T,Zhu D,Zhang K,et al.Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc?-Fc? chimeric protein.J Biol Chem,2003,278:32818-32824.
17. Saxon A,Zhu D,Zhang K,et al.Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases.Curr Opin Allergy Clin Immunol,2004,4:563-568.
18. Allen LC,Kepley CL,Saxon A,et al.Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions.J Allergy Clin Immunol,2007,120:462-468.
19. Zhu D,Kepley CL,Zhang K,et al.A chimeric human-cat fusion protein blocks cat-induced allergy.Nat Med,2005,11:446-449.
20. Zhang K,Zhu D,Kepley CL,et al.Chimeric human fcγ-allergen fusion proteins in the prevention of allergy.Immunol Allergy Clin North Am,2007,27:93-103.
21. Terada T,Zhang K,Belperio J,et al.A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic,pulmonary,and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1,the major cat allergen.Clin Immunol,2006,120:45-56.
  1. 1. Bousquet J,Dahl R,Khaltaev N.Global alliance against chronic respiratory diseases.Allergy,2007,62:216-223.
  2. 2. Holgate S,Casale T,Wenzel S,et al.The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation.J Allergy Clin Immunol,2005,115:459-465.
  3. 3. Bradding P,Walls AF,Holgate ST.The role of the mast cell in the pathophysiology of asthma.J Allergy Clin Immunol,2006,117:1277-1284.
  4. 4. Cruse G,Kaur D,Yang W,et al.Activation of human lung mast cells by monomeric immunoglobulin E.Eur Respir J,2005,25:858-863.
  5. 5. Slavin RG,F(xiàn)erioli C,Tannenbaum SJ,et al.Asthma symptom re-emergence after omalizumab withdrawal correlates well with increasing IgE and decreasing pharmacokinetic concentrations.J Allergy Clin Immunol,2009,123:107-113.
  6. 6. Lin H,Boesel KM,Griffith DT,et al.Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils.J Allergy Clin Immunol,2004,113:297-302.
  7. 7. Djukanovi? R,Wilson SJ,Kraft M,et al.Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma.Am J Respir Crit Care Med,2004,170:583-593.
  8. 8. Soler M.Anti-IgE antibodies in the treatment of allergic diseases.Allergol Immunol Clin,2002,42:45-49. 8 Hayashi N,Tsukamoto Y,Sallas WM,et al.A mechanism-based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab.Br J Clin Pharmacol,2007,63:548-561.
  9. 9. Dodig S,Richter D,Cepelak I.Anti-IgE therapy with omalizumab in asthma and allergic rhinitis.Acta Pharm,2005,55:123-138.
  10. 10. Saxon A,Kepley CL,Zhang K,et al."Accentuate the negative,eliminate the positive":engineering allergy therapeutics to block allergic reactivity through negative signaling.J Allergy Clin Immunol,2008,121:320-325.
  11. 11. Kepley CL,Taghavi S,Mackay G,et al.Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes.J Biol Chem,2004,279:35139-35149.
  12. 12. Daëron M,Malbec O,Latour S,et al.Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.J Clin Invest,1995,95:577-585.
  13. 13. Zhu D,Kepley CL,Zhang K,et al.A novel human immunoglobulin Fcγ–Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation.Nat med,2005,11:446-449.
  14. 14. Zhang K,Kepley CL,Terada T,et al.Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein.J Allergy Clin Immunol,2004,114:321-327.
  15. 15. Kepley CL,Zhang K,Zhu D,et al.Fc?RI-Fc?RII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells.Clin Immunol,2003,108:89-94.
  16. 16. Yamada T,Zhu D,Zhang K,et al.Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc?-Fc? chimeric protein.J Biol Chem,2003,278:32818-32824.
  17. 17. Saxon A,Zhu D,Zhang K,et al.Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases.Curr Opin Allergy Clin Immunol,2004,4:563-568.
  18. 18. Allen LC,Kepley CL,Saxon A,et al.Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions.J Allergy Clin Immunol,2007,120:462-468.
  19. 19. Zhu D,Kepley CL,Zhang K,et al.A chimeric human-cat fusion protein blocks cat-induced allergy.Nat Med,2005,11:446-449.
  20. 20. Zhang K,Zhu D,Kepley CL,et al.Chimeric human fcγ-allergen fusion proteins in the prevention of allergy.Immunol Allergy Clin North Am,2007,27:93-103.
  21. 21. Terada T,Zhang K,Belperio J,et al.A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic,pulmonary,and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1,the major cat allergen.Clin Immunol,2006,120:45-56.
  • 上一篇

    一線三甲醫(yī)院汶川地震420例骨折住院傷員分類(lèi)救治情況分析
  • 下一篇

    汶川地震四川省衛(wèi)生應(yīng)急救援成效分析