目的 探討OSAHS 患者生存質(zhì)量與社會(huì)支持、白天過度嗜睡( EDS) 和多導(dǎo)睡眠圖( PSG) 指標(biāo)等因素的關(guān)系, 尋找影響OSAHS 患者生存質(zhì)量的因素。方法 連續(xù)納入2007 年8 月至 2007 年11 月在華西醫(yī)院睡眠呼吸監(jiān)測(cè)室行多導(dǎo)睡眠圖( PSG) 監(jiān)測(cè)診斷為OSAHS的患者85 例, 分別采用Calgary 生存質(zhì)量指數(shù)( SAQLI) 評(píng)價(jià)生存質(zhì)量, 社會(huì)支持評(píng)定量表( SSRS) 評(píng)價(jià)接受到的社會(huì)支持情況, Epworth嗜睡量表( ESS) 評(píng)價(jià)白天嗜睡程度。用Pearson 直線相關(guān)和多元逐步回歸方法分析SAQLI 評(píng)分與上述因素的關(guān)系。結(jié)果 OSAHS 患者SAQLI 評(píng)分與SSRS 評(píng)分呈正相關(guān)( r = 0. 402,P lt;0. 01) , 與ESS 評(píng)分呈負(fù)相關(guān)( r = - 0. 505, P lt;0. 01) , 與睡眠呼吸暫停低通氣指數(shù)( AHI) 呈負(fù)相關(guān)( r = - 0. 269, P lt;0. 05) , 與夜間最低動(dòng)脈血氧飽和度( LSaO2 ) 呈正相關(guān)( r = 0. 226, P lt;0. 05) 。多元逐步回歸分析最后僅納入了SSRS 和ESS 評(píng)分作為SAQLI 總分的獨(dú)立預(yù)測(cè)變量, 兩者總共可以解釋SAQLI 總分變化的37. 3% ( R2 = 0. 373, P lt; 0. 001) 。結(jié)論 OSAHS 患者生存質(zhì)量與社會(huì)支持、白天過度嗜睡和PSG 指標(biāo)密切相關(guān), 社會(huì)支持和白天過度嗜睡對(duì)OSAHS 患者的生存質(zhì)量的影響較大。
引用本文： 孫凱,梁宗安,王茂筠,雷飛. OSAHS 患者生存質(zhì)量與社會(huì)支持等因素的相關(guān)性研究. 中國呼吸與危重監(jiān)護(hù)雜志, 2009, 09(4): 371-375. doi: 復(fù)制
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| 14. | 中國肥胖問題工作組. 中國成人超重和肥胖癥預(yù)防與控制指南( 節(jié)錄) . 營養(yǎng)學(xué)報(bào), 2004, 26: 1-4. |
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- 1. White DP. Sleep apnea. Proc Am Thorac Soc, 2006, 3: 124-128.
- 2. Yang EH, Hla KM, McHorney CA, et al. Sleep apnea and quality of life. Sleep, 2000, 23: 535-541.
- 3. Shah N, Roux F, Mohsenin V. Improving Health-Related Quality of Life in Patients with Obstructive Sleep Apnea: What are the Available Options? Treat Respir Med, 2006, 5: 235-244.
- 4. Mulgrew AT, Ryan CF, Fleetham JA, et al. The impact of obstructive sleep apnea and daytime sleepiness on work limitation. Sleep Med,2008, 9: 42-53.
- 5. 葉麗川, 梁宗安, 劉春濤. 阻塞性睡眠呼吸暫停綜合征患者生活質(zhì)量與情緒等相關(guān)性研究. 中國呼吸與危重監(jiān)護(hù)雜志, 2004, 3:113-116.
- 6. 孫學(xué)禮, 主編. 醫(yī)學(xué)心理學(xué). 成都: 四川大學(xué)出版社, 2003, 214-216.
- 7. Helgeson VS. Social support and quality of life. Qual Life Res,2003, 12( Suppl 1) : 25-31.
- 8. 中華醫(yī)學(xué)會(huì)呼吸病學(xué)分會(huì)睡眠呼吸疾病學(xué)組. 阻塞性睡眠呼吸暫停低通氣綜合征診治指南( 草案) . 中華內(nèi)科雜志, 2003, 42:594-597.
- 9. Flemons WW, Reimer MA. Development of a disease-specifichealth-related quality of life questionnaire for sleep apnea. Am J Respir Crit Care Med, 1998, 158: 494-503.
- 10. Flemons WW, Reimer MA. Measurement properties of the calgary sleep apnea quality of life index. AmJ Respir Crit Care Med, 2002 ,165: 159-164.
- 11. 肖水源. 《社會(huì)支持評(píng)定量表》的理論基礎(chǔ)與研究應(yīng)用. 臨床精神醫(yī)學(xué)雜志, 1994, 4: 98-100.
- 12. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep, 1991, 14: 540-545.
- 13. Johns MW. Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep, 1992, 15: 376-381.
- 14. 中國肥胖問題工作組. 中國成人超重和肥胖癥預(yù)防與控制指南( 節(jié)錄) . 營養(yǎng)學(xué)報(bào), 2004, 26: 1-4.
- 15. Carno MA, Ellis E, Anson E, et al. Symptoms of Sleep Apnea and Polysomnography as Predictors of Poor Quality of Life in Overweight Children and Adolescents. J Pediatr Psychol, 2007, 33: 269-278.
- 16. Weaver EM, Woodson BT, Steward DL. Polysomnography indexes are discordant with quality of life, symptoms, and reaction times in sleep apnea patients. Otolaryngol Head Neck Surg, 2005 , 132: 255 -262.
- 17. 何權(quán)瀛. 目前我國睡眠呼吸醫(yī)學(xué)面臨的一些困難和問題. 中國呼吸與危重監(jiān)護(hù)雜志, 2007, 6: 81.