目的 探討急性心肌梗死并發(fā)肺水腫患者在機(jī)械通氣支持下, 進(jìn)行緊急冠狀動(dòng)脈介入治療( PCI) 的可行性。方法 回顧性分析2007 至2009 年在急診室確診急性心肌梗死并發(fā)肺水腫, 在機(jī)械通氣支持下行緊急PCI 的15 例患者的病歷資料, 分析其臨床資料、左室射血分?jǐn)?shù)、血漿腦鈉肽( BNP) 及高敏C 反應(yīng)蛋白( hs-CRP) 水平。結(jié)果 15 例患者全部手術(shù)成功, 病情恢復(fù)良好并逐步脫機(jī), 左室射血分?jǐn)?shù)( LVEF) 顯著改善[ 機(jī)械通氣支持介入結(jié)束后EF為( 37. 36 ±0. 02) % , 脫機(jī)前EF為( 47. 41 ±0. 02) % , P lt;0. 05) ; 血漿腦鈉肽水平[ 介入治療前為( 430. 50 ±96. 08) fmol /mL, 介入治療后4 周為( 99. 34 ±5. 15) fmol /mL] 和血清hs-CRP濃度[ 介入治療前為( 89. 50 ±9. 30) ng/mL, 介入治療后4 周為( 8. 35 ±2. 49) ng/mL] 隨治療時(shí)間逐漸降低( P 均 lt; 0. 01) 。結(jié)論 急性心肌梗死肺水腫患者在呼吸機(jī)支持下行緊急PCI 治療具有可行性和較好的療效。
引用本文: 方快發(fā),劉文兵,饒志榮,王寧生,楊友祥. 機(jī)械通氣支持下行緊急介入治療急性心肌梗死并發(fā)肺水腫. 中國(guó)呼吸與危重監(jiān)護(hù)雜志, 2010, 9(3): 281-283. doi: 復(fù)制
版權(quán)信息: ?四川大學(xué)華西醫(yī)院華西期刊社《中國(guó)呼吸與危重監(jiān)護(hù)雜志》版權(quán)所有,未經(jīng)授權(quán)不得轉(zhuǎn)載、改編
1. | 陳方, 計(jì)樂群, 溫寶園, 等. 主動(dòng)脈球囊反搏對(duì)冠心病泵衰竭的治療作用. 中國(guó)介入心臟病學(xué)雜志, 1998, 6: 64-65 . |
2. | Groenning BA, Nilsson JC, Sondergaard L, et al. Evaluation of impaired left ventricular ejection fraction and increased dimensions by muitipule neurohumoral plasma concentyations. Eur J Heart Fail,2001, 3 : 699-708. |
3. | Stanek B, Frey B, Hülsmann M, et al. Prognostic evaluation of neurohumoral plasma levels before and during beta-blocker therapv inadvanced left ventricular dvsfunction. J Am Coll Cardiol, 2001 , 38 :436-442. |
4. | Ridker PM, Hennekens CH, Roitman-Johnson B, et al. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet, 1998 ,351: 88 -92. |
5. | Asada J, Tsuji H, Iwasaka T, et al. Usefulness of plasm a brain natriuretic peptide levels in predicting dobutam ine-induced myocardial ischemia. Am J Cardiol, 2004, 93: 702 -704. |
6. | Hoffmeister HM, Ehlers R, Büttcher E, et al. Relationship between minox myocardial damage and inflammatoxy acute phase reaction in acute coronary syndromes. J Thromb Thrombolysis, 2003, 15 : 33-39. |
7. | 朱蕾, 戎衛(wèi)海, 鈕善福, 等. 經(jīng)面罩機(jī)械通氣治療急性肺水腫的療效觀察. 中國(guó)呼吸與危重監(jiān)護(hù)雜志, 2002, 1: 217-220. |
8. | 朱蕾, 鈕善福, 主編. 機(jī)械通氣. 上海: 上??茖W(xué)技術(shù)出版社,2001, 334 -339. |
- 1. 陳方, 計(jì)樂群, 溫寶園, 等. 主動(dòng)脈球囊反搏對(duì)冠心病泵衰竭的治療作用. 中國(guó)介入心臟病學(xué)雜志, 1998, 6: 64-65 .
- 2. Groenning BA, Nilsson JC, Sondergaard L, et al. Evaluation of impaired left ventricular ejection fraction and increased dimensions by muitipule neurohumoral plasma concentyations. Eur J Heart Fail,2001, 3 : 699-708.
- 3. Stanek B, Frey B, Hülsmann M, et al. Prognostic evaluation of neurohumoral plasma levels before and during beta-blocker therapv inadvanced left ventricular dvsfunction. J Am Coll Cardiol, 2001 , 38 :436-442.
- 4. Ridker PM, Hennekens CH, Roitman-Johnson B, et al. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet, 1998 ,351: 88 -92.
- 5. Asada J, Tsuji H, Iwasaka T, et al. Usefulness of plasm a brain natriuretic peptide levels in predicting dobutam ine-induced myocardial ischemia. Am J Cardiol, 2004, 93: 702 -704.
- 6. Hoffmeister HM, Ehlers R, Büttcher E, et al. Relationship between minox myocardial damage and inflammatoxy acute phase reaction in acute coronary syndromes. J Thromb Thrombolysis, 2003, 15 : 33-39.
- 7. 朱蕾, 戎衛(wèi)海, 鈕善福, 等. 經(jīng)面罩機(jī)械通氣治療急性肺水腫的療效觀察. 中國(guó)呼吸與危重監(jiān)護(hù)雜志, 2002, 1: 217-220.
- 8. 朱蕾, 鈕善福, 主編. 機(jī)械通氣. 上海: 上海科學(xué)技術(shù)出版社,2001, 334 -339.