• 第三軍醫(yī)大學新橋醫(yī)院 全軍心血管外科中心,重慶 400037;

目的 分析采用胸骨下段切口心臟不停跳技術(shù)施行人工二尖瓣置換術(shù)的臨床應(yīng)用情況。 方法 回顧性分析2011年1~12月第三軍醫(yī)大學新橋醫(yī)院42例心瓣膜病患者[胸骨下段切口心臟不停跳手術(shù)組(小切口組)]經(jīng)胸骨下段切口在心臟不停跳下行二尖瓣置換術(shù)的臨床資料,其中男16例,女26例;年齡(42.3±12.7)歲。另隨機選擇我科同期收治的42例心瓣膜病行常規(guī)胸骨正中切口手術(shù)患者作為對照組,其中男18例,女24例;年齡(43.8±13.1) 歲。圍術(shù)期觀察兩組患者的手術(shù)時間、體外循環(huán)時間、主要并發(fā)癥、術(shù)后24 h胸腔引流量、術(shù)后皮膚切口長度以及術(shù)后住院時間等,并進行比較?!〗Y(jié)果 圍術(shù)期兩組均無死亡。小切口組患者術(shù)后早期無再次開胸止血、完全性房室傳導(dǎo)阻滯、栓塞和瓣周漏等并發(fā)癥發(fā)生。兩組體外循環(huán)時間、手術(shù)時間、二次開胸止血、傷口感染率和瓣周漏發(fā)生率差異均無統(tǒng)計學意義(P>0.05);但小切口組皮膚切口長度較對照組皮膚切口長度平均縮短5.2 cm [(7.9±1.4) cm vs. (13.1±3.3) cm,P=0.000],術(shù)后24 h出血量明顯減少[(183.6±40.2) ml vs. (273.4±59.9)ml,P=0.000],術(shù)后住院時間明顯縮短[(8.1±1.3) d vs. (10.6±2.1) d,P=0.000] 。術(shù)后小切口組隨訪40例,隨訪時間3~15個月,失訪2例;傷口疼痛4例,多數(shù)患者術(shù)后瘢痕發(fā)生率低,生活質(zhì)量良好。對照組隨訪38例,隨訪時間3~15個月,失訪4例;傷口疼痛17例?!〗Y(jié)論 經(jīng)胸骨下段切口在心臟不停跳下行二尖瓣置換術(shù)可減輕手術(shù)創(chuàng)傷、簡化操作、提高手術(shù)療效,是一種安全、有效以及美觀的手術(shù)方式。

引用本文: 程偉,肖穎彬,陳林,劉泓. 胸骨下段切口心臟不停跳技術(shù)在 二尖瓣置換術(shù)中的應(yīng)用. 中國胸心血管外科臨床雜志, 2013, 20(1): 33-36. doi: 復(fù)制

1. Magalhães MG, Alves LM, Alcantara LF, et al. Post-operative mediastinitis in a heart hospital of Recife:contributions for nursing care. Rev Esc Enferm USP, 2012, 46 (4):865-871.
2. Tiveron MG, Fiorelli AI, Mota EM, et al. Preoperative risk factors for mediastinitis after cardiac surgery:analysis of 2768 patients. Rev Bras Cir Cardiovasc, 2012, 27 (2):203-210.
3. Kim HS, Kim KB, Hwang HY, et al. Subxiphoid incisional hernia development after coronary artery bypass grafting. Korean J Thorac Cardiovasc Surg, 2012, 45 (3):161-165.
4. 胡義杰, 鐘前進, 陳建明, 等. 右側(cè)腋下小切口先天性心臟病直視手術(shù)的臨床應(yīng)用. 中國胸心血管外科臨床雜志, 2012, 19 (4):427-429.
5. 何發(fā)明, 王平凡, 梁志強, 等. 右腋下小切口心臟直視手術(shù)3 012例的臨床應(yīng)用. 中國胸心血管外科臨床雜志, 2010, 17 (3):247-249.
6. Murashita T, Hatta E, Ooka T, et al. Minimal access surgery for the repair of simple congenital heart defects:factors affecting hospital stay after surgery. Thorac Cardiovasc Surg, 2004, 52 (3):127-134.
7. Cherup LL, Siewers RD, Futrell JW. Breast and pectoral muscle maldevelopment after anterolateral and posterolateral thoracotomies in children. Ann Thorac Surg, 1986, 41 (5):492-497.
8. Massetti M, Babatasi G, Rossi A, et al. Operation for atrial septal defect through a right anterolateral thoracotomy:current outcome. Ann Thorac Surg, 1996, 62 (4):1100-1103.
9. Grinda JM, Folliguet TA, Dervanian P, et al. Right anterolateral thoracotomy for repair of atrial septal defect. Ann Thorac Surg, 1996, 62 (1):175-178.
10. Benetti F, Prapas S, Angeletti E, et al. Xiphoid lower-sternotomy approach for multivessel revascularization of the left internal mammary  artery to the left anterior descending artery and right internal mammary artery inflow to the other vessels. Heart Surg Forum, 2010, 13 (1):E36-E39.
11. Takata M, Watanabe G, Ushijima T, et al. A novel internal thoracic artery harvesting technique via subxiphoid approach——for the least invasive coronary artery bypass grafting. Interact Cardiovasc Thorac Surg, 2009, 9 (5):891-892. 12 Niinami H, Takeuchi Y, Ichikawa S, et al. Partial median sternotomy  as a minimal access for off-pump coronary artery bypass grafting:feasibility of the lower-end sternal splitting approach. Ann Thorac Surg, 2001, 72 (3):S1041-S1045.
12. Tamis-Holland JE, Homel P, Durani M, et al. Atrial fibrillation after minimally invasive direct coronary artery bypass surgery. J Am Coll Cardiol, 2000, 36 (6):1884-1888.
13. Karthekeyan BR, Vakamudi M, Thangavelu P, et al. Lower ministernotomy and fast tracking for atrial septal defect. Asian Cardiovasc Thorac Ann, 2010, 18 (2):166-169.
14. Castro NJ, Melo E, Fernandes J, et al. Mitral valve and atrial septal defect surgery:minimally invasive or sternotomy approach. Arq Bras Cardiol, 2012, 99 (2):681-687.
15. Mcclure RS, Cohn LH, Wiegerinck E, et al. Early and late outcomes in minimally invasive mitral valve repair:an eleven-year experience in 707 patients. J Thorac Cardiovasc Surg, 2009, 137 (1):70-75.
16. Massetti M, Babatasi G, Bhoyroo S, et al. A special adapted retractor for the mini-sternotomy approach. Ann Thorac Surg, 1999, 68 (1):274-277.
17. Borowski A, Korb H. Myocardial protection by pressure-and volume-controlled continuous hypothermic coronary perfusion (PVC-CONTHY-CAP) in combination with ultra-short beta-blockade and nitroglycerine. Thorac Cardiovasc Surg, 1997, 45 (2):51-54.
18. Wang J, Liu HY, Xiang B, et al. Keeping the heart empty and beating improves preservation of hypertrophied hearts for valve surgery. J Thorac Cardiovasc Surg, 2006, 132 (6):1314-1320.
19. Mo A, Lin H, Wen Z, et al. Efficacy and safety of on-pump beating heart surgery. Ann Thorac Surg, 2008 , 86 (6):1914-1918.
20. Gersak B, Sutlic Z. Aortic and mitral valve surgery on the beating heart is lowering cardiopulmonary bypass and aortic cross clamp time. Heart Surg Forum, 2002, 5 (2):182-186.
21. Gersak B. Mitral valve repair or replacement on the beating heart. Heart Surg Forum, 2000, 3 (3):232-237.
22. Cicekcioglu F, Tutun U, Babaroglu S, et al. Aortic valve replacement with on-pump beating heart technique. J Card Surg, 2007, 22 (3):211-214.
23. Wan S, De Smet JM, Barvais L, et al. Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg, 1996, 112 (3):806-811.
24. Karadeniz U, Erdemli O, Yamak B, et al. On-pump beating heart versus hypothermic arrested heart valve replacement surgery. J Card Surg, 2008, 23 (2):107-113.
25. 肖穎彬, 陳林, 王學鋒, 等. 淺低溫體外循環(huán)心臟跳動中心內(nèi)直視手術(shù)1032例臨床分析. 第三軍醫(yī)大學學報, 2001, 23 (5):502-504.
  1. 1. Magalhães MG, Alves LM, Alcantara LF, et al. Post-operative mediastinitis in a heart hospital of Recife:contributions for nursing care. Rev Esc Enferm USP, 2012, 46 (4):865-871.
  2. 2. Tiveron MG, Fiorelli AI, Mota EM, et al. Preoperative risk factors for mediastinitis after cardiac surgery:analysis of 2768 patients. Rev Bras Cir Cardiovasc, 2012, 27 (2):203-210.
  3. 3. Kim HS, Kim KB, Hwang HY, et al. Subxiphoid incisional hernia development after coronary artery bypass grafting. Korean J Thorac Cardiovasc Surg, 2012, 45 (3):161-165.
  4. 4. 胡義杰, 鐘前進, 陳建明, 等. 右側(cè)腋下小切口先天性心臟病直視手術(shù)的臨床應(yīng)用. 中國胸心血管外科臨床雜志, 2012, 19 (4):427-429.
  5. 5. 何發(fā)明, 王平凡, 梁志強, 等. 右腋下小切口心臟直視手術(shù)3 012例的臨床應(yīng)用. 中國胸心血管外科臨床雜志, 2010, 17 (3):247-249.
  6. 6. Murashita T, Hatta E, Ooka T, et al. Minimal access surgery for the repair of simple congenital heart defects:factors affecting hospital stay after surgery. Thorac Cardiovasc Surg, 2004, 52 (3):127-134.
  7. 7. Cherup LL, Siewers RD, Futrell JW. Breast and pectoral muscle maldevelopment after anterolateral and posterolateral thoracotomies in children. Ann Thorac Surg, 1986, 41 (5):492-497.
  8. 8. Massetti M, Babatasi G, Rossi A, et al. Operation for atrial septal defect through a right anterolateral thoracotomy:current outcome. Ann Thorac Surg, 1996, 62 (4):1100-1103.
  9. 9. Grinda JM, Folliguet TA, Dervanian P, et al. Right anterolateral thoracotomy for repair of atrial septal defect. Ann Thorac Surg, 1996, 62 (1):175-178.
  10. 10. Benetti F, Prapas S, Angeletti E, et al. Xiphoid lower-sternotomy approach for multivessel revascularization of the left internal mammary  artery to the left anterior descending artery and right internal mammary artery inflow to the other vessels. Heart Surg Forum, 2010, 13 (1):E36-E39.
  11. 11. Takata M, Watanabe G, Ushijima T, et al. A novel internal thoracic artery harvesting technique via subxiphoid approach——for the least invasive coronary artery bypass grafting. Interact Cardiovasc Thorac Surg, 2009, 9 (5):891-892. 12 Niinami H, Takeuchi Y, Ichikawa S, et al. Partial median sternotomy  as a minimal access for off-pump coronary artery bypass grafting:feasibility of the lower-end sternal splitting approach. Ann Thorac Surg, 2001, 72 (3):S1041-S1045.
  12. 12. Tamis-Holland JE, Homel P, Durani M, et al. Atrial fibrillation after minimally invasive direct coronary artery bypass surgery. J Am Coll Cardiol, 2000, 36 (6):1884-1888.
  13. 13. Karthekeyan BR, Vakamudi M, Thangavelu P, et al. Lower ministernotomy and fast tracking for atrial septal defect. Asian Cardiovasc Thorac Ann, 2010, 18 (2):166-169.
  14. 14. Castro NJ, Melo E, Fernandes J, et al. Mitral valve and atrial septal defect surgery:minimally invasive or sternotomy approach. Arq Bras Cardiol, 2012, 99 (2):681-687.
  15. 15. Mcclure RS, Cohn LH, Wiegerinck E, et al. Early and late outcomes in minimally invasive mitral valve repair:an eleven-year experience in 707 patients. J Thorac Cardiovasc Surg, 2009, 137 (1):70-75.
  16. 16. Massetti M, Babatasi G, Bhoyroo S, et al. A special adapted retractor for the mini-sternotomy approach. Ann Thorac Surg, 1999, 68 (1):274-277.
  17. 17. Borowski A, Korb H. Myocardial protection by pressure-and volume-controlled continuous hypothermic coronary perfusion (PVC-CONTHY-CAP) in combination with ultra-short beta-blockade and nitroglycerine. Thorac Cardiovasc Surg, 1997, 45 (2):51-54.
  18. 18. Wang J, Liu HY, Xiang B, et al. Keeping the heart empty and beating improves preservation of hypertrophied hearts for valve surgery. J Thorac Cardiovasc Surg, 2006, 132 (6):1314-1320.
  19. 19. Mo A, Lin H, Wen Z, et al. Efficacy and safety of on-pump beating heart surgery. Ann Thorac Surg, 2008 , 86 (6):1914-1918.
  20. 20. Gersak B, Sutlic Z. Aortic and mitral valve surgery on the beating heart is lowering cardiopulmonary bypass and aortic cross clamp time. Heart Surg Forum, 2002, 5 (2):182-186.
  21. 21. Gersak B. Mitral valve repair or replacement on the beating heart. Heart Surg Forum, 2000, 3 (3):232-237.
  22. 22. Cicekcioglu F, Tutun U, Babaroglu S, et al. Aortic valve replacement with on-pump beating heart technique. J Card Surg, 2007, 22 (3):211-214.
  23. 23. Wan S, De Smet JM, Barvais L, et al. Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg, 1996, 112 (3):806-811.
  24. 24. Karadeniz U, Erdemli O, Yamak B, et al. On-pump beating heart versus hypothermic arrested heart valve replacement surgery. J Card Surg, 2008, 23 (2):107-113.
  25. 25. 肖穎彬, 陳林, 王學鋒, 等. 淺低溫體外循環(huán)心臟跳動中心內(nèi)直視手術(shù)1032例臨床分析. 第三軍醫(yī)大學學報, 2001, 23 (5):502-504.