• 四川大學(xué)華西醫(yī)院中國(guó)循證醫(yī)學(xué)中心,Chinese Cochrane Centre,INCLEN地區(qū)資源與培訓(xùn)中心,中國(guó)臨床試驗(yàn)注冊(cè)中心 (成都 610041);

闡述了 NNT 和 NNH 的定義和用途。NNT 用于治療前評(píng)估不治療給患者造成損害的可能性,NNH 用于評(píng)估治療可能給患者造成傷害的可能性,也可用于比較干預(yù)措施與陽(yáng)性藥物比較的相對(duì)獲益或受損。與安慰劑比較時(shí), NNT或NNH 為絕對(duì)效應(yīng)量;與陽(yáng)性藥物比較時(shí),NNT 或 NNH 為相對(duì)效應(yīng)量。當(dāng)描述相對(duì)效應(yīng)量時(shí),通過(guò)RR或 OR、RD表示干預(yù)措施與對(duì)照的效應(yīng)量大小關(guān)系。

引用本文: 吳泰相,劉關(guān)鍵. NNT和NNH的概念及應(yīng)用. 中國(guó)循證醫(yī)學(xué)雜志, 2007, 07(9): 669-672. doi: 復(fù)制

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