目的 從循證醫(yī)學(xué)角度探討1 例妊娠期糖尿病患者的預(yù)后。
方法 計算機(jī)檢索ACP Journal Club （1991 ～ 2006 年10 月）、Cochrane 圖書館（2006 年第4 期）、MEDLINE（1990 ～ 2006 年10 月）和中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫，查找妊娠期糖尿病預(yù)后的隊(duì)列研究、病例 - 對照研究和病例系列研究等，并對所獲證據(jù)的質(zhì)量進(jìn)行評價。
結(jié)果 臨床證據(jù)表明，妊娠期糖尿病患者結(jié)束妊娠后 6 周至 28 年，2 型糖尿病的發(fā)病率為 2.6% ～ 70%，發(fā)生自發(fā)性早產(chǎn)的幾率為 6.7％，患高血壓和代謝綜合征的比例增加，有感染陰道念珠菌的危險。
結(jié)論 患妊娠期糖尿病的婦女較未患糖尿病的孕婦結(jié)束妊娠后糖尿病的患病率增加，自發(fā)性早產(chǎn)、高血壓、代謝綜合征及陰道感染等并發(fā)癥發(fā)病率增加。但其長期終點(diǎn)事件發(fā)生率有待進(jìn)一步研究。
引用本文： 李峻,吳惠. 1例妊娠期糖尿病患者預(yù)后的臨床證據(jù). 中國循證醫(yī)學(xué)雜志, 2007, 07(9): 690-693. doi: 復(fù)制
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| 9. | Lauenborg J, Mathiesen E, Hansen T, et al. The prevalence of the metabol ic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population. J Clin Endocrinol Metab, 2005, 90 (7): 4004-4010. |
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- 1. Goldman M, Kitzmiller, Abrams B, et al. Obsteric complication with GDM. Diabetes, 1991, 40(2): 79-82.
- 2. Avery MD, Rossi MA. Gestational diabetes. J Nurse Midwifery, 1994, 39(2 Suppl): 9s-19s.
- 3. Sackett DL, Straus SE, Richardson WS, et al. Chief editor. Evidence-based medicine: how to practice and teach EBM, 2nd edition. London: Churchill Livingstone. 2000.
- 4. 李幼平, 主編. 循證醫(yī)學(xué). 第1版. 北京: 高等教育出版社, 2003. 20-21.Li YP, Chief editor. Evidence-Based Medicine. 1st eds. Beijing: Higher Education Press, 2003. 20-21.
- 5. Kim C, Newton KM, Knopp RH. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care, 2002, 25(10): 1862-1868.
- 6. Keshavarz M, Cheung NW, Babaee GR, et al. Gestational diabetes in iran: incidence, risk factors and pregnancy outcomes. Diabetes Res Clin Pract, 2005, 69(3): 279-286.
- 7. Hedderson MM, Ferrara A, Sacks DA. Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: association with increased risk of spontaneous preterm birth. Obstet Gynecol, 2003, 102(4): 850-856.
- 8. Lauenborg J, Hansen T, Jensen DM, et al. Increasing Incidence of Diabetes After Gestational Diabetes. A long-term follow-up in a Danish population. Diabetes Care, 2004, 27(5): 1194-1199.
- 9. Lauenborg J, Mathiesen E, Hansen T, et al. The prevalence of the metabol ic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population. J Clin Endocrinol Metab, 2005, 90 (7): 4004-4010.
- 10. Odar E, Wandabwa J, Kiondo P. Maternal and fetal outcome of gestational diabetes mellitus in Mulago Hospital, Uganda. Afr Health Sci, 2004, 4(1): 9-14.