目的 研究腦電雙頻指數(shù)（BIS）在小兒麻醉中的應(yīng)用，為BIS在小兒臨床麻醉上的廣泛應(yīng)用及提高小兒麻醉的安全性提供依據(jù)。 方法 2011年1月－3月擬行腹部外科手術(shù)的患兒60例，男39例，女21例；年齡1～4歲，美國麻醉醫(yī)師協(xié)會分級Ⅰ～Ⅱ級，隨機(jī)分為兩組，每組各30例。S組：七氟醚、瑞芬太尼和維庫溴銨維持麻醉；P組：丙泊酚、瑞芬太尼和維庫溴銨維持麻醉。采用BIS監(jiān)測麻醉深度，將BIS控制在50 ± 5，記錄麻醉誘導(dǎo)前到手術(shù)探查期間不同時點的血流動力學(xué)參數(shù)及蘇醒、拔管時間。 結(jié)果 手術(shù)過程中P組血壓及心率明顯低于麻醉前水平（P＜0.05）。S組蘇醒迅速、完全，蘇醒時間與P組比較差異有統(tǒng)計學(xué)意義（P＜0.05）。S組的血流動力學(xué)穩(wěn)定性優(yōu)于P組，蘇醒時間、拔管時間相對較短。麻醉誘導(dǎo)前兩組的BIS值均為97 ± 1，意識消失時的BIS值為71 ± 2。BIS值為50 ± 5時，結(jié)果顯示手術(shù)過程中（T4、T5、T6、T7）兩組的心率、血壓都很平穩(wěn)。 結(jié)論 BIS作為小兒麻醉鎮(zhèn)靜深度的監(jiān)測指標(biāo)有臨床意義。
引用本文： 陳春燕,李超,成黎明. 腦電雙頻指數(shù)在小兒麻醉中的應(yīng)用. 華西醫(yī)學(xué), 2012, 27(4): 552-554. doi: 復(fù)制
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| 12. | 王培, 冀翔宇, 王世端, 等. 七氟醚與異丙酚麻醉BIS 為50時血流動力學(xué)參數(shù)變化[J]. 齊魯醫(yī)學(xué)雜志, 2010, 10(25): 424-427. |
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- 1. 李靜潔. 腦電雙頻指數(shù)用于兒科麻醉深度監(jiān)測[J]. 上海第二醫(yī)科大學(xué)學(xué)報, 2003, 5(23): 470-472.
- 2. 莊心良. 現(xiàn)代麻醉學(xué)[M]. 北京: 人民衛(wèi)生出版社, 2003: 481.
- 3. Doi M, Gajraj RJ, Mantzaridis H, et al. Relationship between calculated blood concentration of propofol and electrophysiological variables during emergence from anaesthesia: comparison of bispectral index, spectral edge frequency, median frequency and auditory evoked potential index[J]. Br J Anaesth, 1997, 78(2): 180-184.
- 4. 韋天全. 小兒麻醉深度監(jiān)測研究現(xiàn)狀[J]. 廣西醫(yī)學(xué), 2010, 4(32): 466-468.
- 5. 于布為. 麻醉深度監(jiān)測進(jìn)展[J]. 中國醫(yī)療器械信息, 2005, 11(6): 5-10.
- 6. Powers KS, Nazarian EB, Tapyrik SA, et al. Bispectral index as a guide for titration of propofol during procedural sedation among children[J]. Pediatrics, 2005, 115(6): 1666-1674.
- 7. Olson DM, Cheek DJ, Morgenlander JC. The impact of bispectral index monitoring on rates of propofol administration[J]. AACN Clin Issues, 2004, 15(1): 63-73.
- 8. Levine DA, Platt SL. Novel monitoring techniques for use with procedural sedation[J]. Pediatrics, 2005, 17(3): 351-354.
- 9. Ganesh A, Watcha MF. Bispectral index monitoring in pediatric anesthesia[J]. Anaesthesiology, 2004, 17 (3): 229-234.
- 10. Sadhasivam S, Ganesh A, Robison A, et al. Validation of the bispectral index monitor for measuring the depth of sedation in children[J], Anesth Analg, 2006, 102(2): 383-388.
- 11. Muñoz HR, León PJ, Fuentes RS, et al. Prospective evaluation of the time to peak effect of propofol to target the effect site in children[J]. Acta Anaesthesiol Scand, 2009, 53(7): 883-890.
- 12. 王培, 冀翔宇, 王世端, 等. 七氟醚與異丙酚麻醉BIS 為50時血流動力學(xué)參數(shù)變化[J]. 齊魯醫(yī)學(xué)雜志, 2010, 10(25): 424-427.
- 13. 曲良超, 肖實, 郭善亮, 等. 腦電雙頻指數(shù)反饋調(diào)控丙泊酚靶控輸注在小兒先心病手術(shù)中的應(yīng)用[J]. 臨床麻醉學(xué)雜志, 2010, 5(26): 400-402.