• 四川大學(xué)華西醫(yī)院神經(jīng)外科(成都,610041);

目的  探討延髓腫瘤的治療策略,以達(dá)到最佳預(yù)后。 方法  回顧分析2007年1月-2010年12月19例延髓腫瘤患者的臨床資料,其中18例經(jīng)外科手術(shù)治療和病理證實(shí),1例通過影像學(xué)確診。 結(jié)果  12例血管網(wǎng)狀細(xì)胞瘤中,11例手術(shù)全切,1例手術(shù)次全切;2例室管膜瘤均手術(shù)全切;2例海綿狀血管瘤分別手術(shù)全切及伽馬刀治療;3例膠質(zhì)瘤均手術(shù)部分切除。18例手術(shù)治療患者術(shù)后神經(jīng)功能障礙明顯好轉(zhuǎn)者13例,無明顯變化者3例,2例因術(shù)后嚴(yán)重并發(fā)癥死亡;1例伽馬刀治療患者癥狀好轉(zhuǎn)。術(shù)后隨訪6~48個(gè)月,平均24個(gè)月。11例恢復(fù)工作,4例生活可自理,2例因腫瘤復(fù)發(fā)死亡。結(jié)論  術(shù)前通過MRI檢查、術(shù)中神經(jīng)電生理監(jiān)測(cè)及熟練的顯微外科技術(shù)是外科治療優(yōu)勢(shì),伽馬刀治療延髓較小腫瘤有著損傷小的優(yōu)點(diǎn),因此制定合理的治療策略有利于提高患者生存質(zhì)量。

引用本文: 郝德,楊翔,張躍康. 延髓腫瘤的臨床分析. 華西醫(yī)學(xué), 2012, 27(6): 885-888. doi: 復(fù)制

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3.  周良輔, 杜固宏, 毛穎, 等. 腦干血管母細(xì)胞瘤的診斷和治療[J]. 中華神經(jīng)外科雜志, 2004, 20(2): 127-131.
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5.  Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
6.  Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
7.  王恩敏, 張南, 王濱江. 伽瑪?shù)吨委熝苣讣?xì)胞瘤臨床分析[J]. 中華外科雜志, 2003, 41(9): 516-520.
8.  Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.
  1. 1.  Dan SH, James Z, Donlin M. Surgical resection of intrinsic brain steml lesions: an overview[J]. Neurosurgery, 1990, 27(5): 789-798.
  2. 2.  Chang UK, ChoeWJ, Chung SK, et al. Surgical outcome and prognostic factors of spinal intramedullary ependymomas in adults[J]. J Neurooncol, 2002, 57(2): 133-139.
  3. 3.  周良輔, 杜固宏, 毛穎, 等. 腦干血管母細(xì)胞瘤的診斷和治療[J]. 中華神經(jīng)外科雜志, 2004, 20(2): 127-131.
  4. 4.  Wang C, Zhang J, Liu A, et al. Surgical management of medullary hemangioblastoma. Report of 47 cases [J]. Surg Neurol, 2001, 56(4): 218-227.
  5. 5.  Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
  6. 6.  Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
  7. 7.  王恩敏, 張南, 王濱江. 伽瑪?shù)吨委熝苣讣?xì)胞瘤臨床分析[J]. 中華外科雜志, 2003, 41(9): 516-520.
  8. 8.  Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.