• 遂寧市中心醫(yī)院消化內(nèi)鏡室（四川遂寧，629000）;

【摘要】　目的　 探討膠囊內(nèi)鏡對(duì)小腸疾病的診斷價(jià)值及順應(yīng)性和安全性。　方法　 分析2009年4月-2010年3月對(duì)35例疑有小腸疾病者行膠囊內(nèi)鏡檢查的臨床資料。　結(jié)果　 35例中發(fā)現(xiàn)小腸病變26例 （74.3%），包括血管畸形9例，間質(zhì)瘤1例，息肉2例，小潰瘍 1例，非特異性炎癥 11例，寄生蟲2例，其中 4例患者同時(shí)存在兩種病變。所獲取的圖像質(zhì)量良好。膠囊胃內(nèi)運(yùn)行平均時(shí)間為 62 min（5～460 min），小腸運(yùn)行時(shí)間為 347 min（103～538 min），平均到達(dá)盲腸時(shí)間為384 min （120～540 min），平均記錄時(shí)間為547 min（299～605 min），平均獲取照片數(shù)為54 766張，膠囊排出體外時(shí)間平均為33 h（10～120 h）。受檢者順應(yīng)性良好，無任何并發(fā)癥發(fā)生。　結(jié)論　 膠囊內(nèi)鏡是一種對(duì)小腸疾病具有較高的檢出能力；其安全性高、順應(yīng)性好 。
【Abstract】　Objective　 To investigate the diagnostic value of capsule endoscope for small intestine diseases, and to evaluate the compliance and security of capsule endoscopy.　Methods　 The clinical data of 35 patients who underwent capsule endoscopy due to small bowel diseases between April 2009 and March 2010 were retrospectively analyzed.　Results　 In the 35 patients, 26 (74.3%) had intestine diseases including vascular malformation in nine, interstitialoma in one, polyp in two, aphtha in one, non-specific inflammation in 11 and parasite in two; 4 patients had two lesions simultaneously. The quality of the obtained images was good. The average running time of the capsules in the stomach ranged from five to 460 minutes with an average time of 62 minutes. The running time of the capsules in the small intestine ranged from 103 to 538 minutes with an average of 347 minutes. The running time of the capsules arriving at the cecum ranged from 103 to 538 minutes with an average of 347 minutes. The time of the capsules egested out ranged from 10 to 120 hours with an average of 33 hours. The recording time ranged from 299 to 605 minuets with an average of 547 minutes. The mean acquired images were 54 766 pieces, The patients had good compliance, and none had any complications.　Conclusion　 The capsule endoscopy had high security and good compliance. It has high detectivity in diagnosing small intestine diseases.

引用本文： 龍曉奇,陳擁軍,唐毅,陳亮,楊彬,余小燕,李茂芝. 膠囊內(nèi)鏡在小腸疾病診斷的臨床應(yīng)用. 華西醫(yī)學(xué), 2011, 26(2): 184-186. doi: 復(fù)制

1. 　Pennazio M. Small-bowel endoscopy[J]. Endoscopy, 2004, 36(1): 32-41.
2. 　Appleyard M, Fireman Z, Glukhovsky A, et al. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions[J]. Gastroenterology, 2000, 119(6): 1431-1438.
3. 　Yamamoto H, Kita H, Scenada K, et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of smail-intestinal diseases[J].Clin Gastroenterol Hepatol, 2004, 2(11): 1010-1016.
4. 　郭永紅, 龍利民, 王海琴, 等. 老年人膠囊內(nèi)鏡檢查的臨床應(yīng)用[J]. 中國內(nèi)鏡雜志, 2007, 13(3): 285-289.
5. 　戈之錚, 胡運(yùn)彪, 高云杰. 膠囊內(nèi)鏡的臨床應(yīng)用[J]. 中華消化雜志, 2003, 23 (1): 7-10.
6. 　馮桂建, 劉玉蘭. 膠囊內(nèi)鏡的發(fā)展和應(yīng)用[J]. 中國消化內(nèi)鏡, 2007, 1(2): 16.
7. 　張子其, 陳孝. 膠囊內(nèi)鏡對(duì)小腸疾病的診斷價(jià)值[J]. 中國實(shí)用內(nèi)科雜志, 2005, 25(3): 218.
8. 　褚嘩, 吳云林, 張曙, 等. 消化道出血患者的膠囊內(nèi)鏡檢查[J]. 上海第二醫(yī)科大學(xué)學(xué)報(bào), 2005, 25(9): 886.
9. 　Iddan G, Meron G, Glukhovsky A, et al. Wireless capsule endoscopy[J]. Nature, 2000, 405(6785): 417.
10. 　趙銳, 伍麗萍, 溫忠慧, 等. OMOM膠囊內(nèi)鏡在老年患者消化道疾病診斷中的應(yīng)用[J]. 華西醫(yī)學(xué), 2010, 25(1): 121-123.
11. 　Nakamura M, Niwa Y, Ohmiya N, et al. Preliminary comparison of capsule endoscopy and double-balloon enteroscopy in patients with suspected small-bowel bleeding[J]. Endoscopy, 2006, 38(1): 59-66.
12. 　Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases[J]. Gastroenterology, 2004, 126(3): 643-653.
13. 　楊偉昂, 王炳周, 吳靈飛. 膠囊內(nèi)鏡臨床應(yīng)用新進(jìn)展[J]. 世界華人消化雜志, 2008, 16(36): 4085.
  1. 1. 　Pennazio M. Small-bowel endoscopy[J]. Endoscopy, 2004, 36(1): 32-41.
  2. 2. 　Appleyard M, Fireman Z, Glukhovsky A, et al. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions[J]. Gastroenterology, 2000, 119(6): 1431-1438.
  3. 3. 　Yamamoto H, Kita H, Scenada K, et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of smail-intestinal diseases[J].Clin Gastroenterol Hepatol, 2004, 2(11): 1010-1016.
  4. 4. 　郭永紅, 龍利民, 王海琴, 等. 老年人膠囊內(nèi)鏡檢查的臨床應(yīng)用[J]. 中國內(nèi)鏡雜志, 2007, 13(3): 285-289.
  5. 5. 　戈之錚, 胡運(yùn)彪, 高云杰. 膠囊內(nèi)鏡的臨床應(yīng)用[J]. 中華消化雜志, 2003, 23 (1): 7-10.
  6. 6. 　馮桂建, 劉玉蘭. 膠囊內(nèi)鏡的發(fā)展和應(yīng)用[J]. 中國消化內(nèi)鏡, 2007, 1(2): 16.
  7. 7. 　張子其, 陳孝. 膠囊內(nèi)鏡對(duì)小腸疾病的診斷價(jià)值[J]. 中國實(shí)用內(nèi)科雜志, 2005, 25(3): 218.
  8. 8. 　褚嘩, 吳云林, 張曙, 等. 消化道出血患者的膠囊內(nèi)鏡檢查[J]. 上海第二醫(yī)科大學(xué)學(xué)報(bào), 2005, 25(9): 886.
  9. 9. 　Iddan G, Meron G, Glukhovsky A, et al. Wireless capsule endoscopy[J]. Nature, 2000, 405(6785): 417.
  10. 10. 　趙銳, 伍麗萍, 溫忠慧, 等. OMOM膠囊內(nèi)鏡在老年患者消化道疾病診斷中的應(yīng)用[J]. 華西醫(yī)學(xué), 2010, 25(1): 121-123.
  11. 11. 　Nakamura M, Niwa Y, Ohmiya N, et al. Preliminary comparison of capsule endoscopy and double-balloon enteroscopy in patients with suspected small-bowel bleeding[J]. Endoscopy, 2006, 38(1): 59-66.
  12. 12. 　Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases[J]. Gastroenterology, 2004, 126(3): 643-653.
  13. 13. 　楊偉昂, 王炳周, 吳靈飛. 膠囊內(nèi)鏡臨床應(yīng)用新進(jìn)展[J]. 世界華人消化雜志, 2008, 16(36): 4085.