• 四川大學(xué)華西第二醫(yī)院婦產(chǎn)科(成都,610041);

【摘要】 目的  探討子宮頸巨大平滑肌瘤在其診斷及治療上的特殊性。 方法  對(duì)2007年10月-2010年3月收治的11例子宮頸巨大平滑肌瘤患者的臨床資料進(jìn)行分析,對(duì)其發(fā)病率,診斷和手術(shù)治療進(jìn)行評(píng)價(jià)。 結(jié)果  11例子宮頸巨大平滑肌瘤中黏膜下2例,腹膜后9例。術(shù)前9例出現(xiàn)誤診,其中誤診為盆腔包塊5例,子宮體肌瘤3例,子宮肉瘤1例。6例行經(jīng)腹子宮全切加雙附件切除,2例行經(jīng)腹子宮切除術(shù),1例行經(jīng)腹肌瘤挖除術(shù),1例行經(jīng)陰道肌瘤摘除術(shù),1例行經(jīng)腹肌瘤挖出加宮頸殘端切除術(shù)。 結(jié)論  子宮頸巨大平滑肌瘤由于其位置的特殊性,尤其是凸向腹膜后的肌瘤,由于盆腔器官被擠壓,使盆腔解剖結(jié)構(gòu)發(fā)生改變,術(shù)前易被誤診。且手術(shù)過(guò)程中易出現(xiàn)損傷及出血,因此術(shù)前估計(jì)充分,術(shù)中仔細(xì)認(rèn)清各器官解剖關(guān)系,可有效地減少術(shù)中損傷和控制出血。
【Abstract】 Objective  To investigate the particularity of diagnosis and treatment for giant uterine cervical leiomyoma. Methods  We analyzed the clinical data of 11 patients with giant uterine cervical leiomyoma who were admitted in our hospital from October 2007 to March 2010. The incidence, diagnosis and surgical treatment of the disease were evaluated. Results  Of the 11 cases, nine were retroperitoneal leiomyoma and two were submucous leiomyoma. There were nine misdiagnosed cases before operation, including five diagnosed as pelvic mass, one as uterine sarcoma and three as uterine corpus leiomyoma. Six patients underwent abdominal hysterectomy and bilateral salpingo-oophorectomy; two underwent abdominal hysterectomy; one underwent abdominal myomectomy; one underwent transvaginal myomectomy; and one underwent abdominal myomectomy with excision of cervical stump. Conclusion  The giant uterine cervical leiomyoma is easily misdiagnosed preoperatively due to its special anatomic site. A good example is the retroperitoneal leiomyoma in which the pelvic anatomic structure is changed because of the extrusion of the tumor on other pelvic organs. Furthermore, injuries and bleeding often happen during the operation. Consequently, sufficient preoperative assessment and clearly identifying regional anatomical relations can effectively reduce the damage and bleeding during the operation.

引用本文: 馮丹,方芳. 子宮頸巨大平滑肌瘤的臨床分析. 華西醫(yī)學(xué), 2011, 26(3): 385-387. doi: 復(fù)制

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2.  林巧稚. 婦科腫瘤[M]. 北京: 人民出版社, 1982: 64.
3.  沈浣. 宮頸肌瘤58例臨床分析[J]. 中國(guó)實(shí)用婦科與產(chǎn)科雜志, 1991, 15(6): 300.
4.  馮令達(dá), 邵敬於, 朱萬(wàn)里. 69例宮頸肌瘤的手術(shù)途徑及術(shù)式研究[J]. 腫瘤, 2001, 21(4): 297-299.
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6.  曾桂英. 子宮頸部肌瘤36例分析[J]. 中華今日醫(yī)學(xué)雜志, 2004, 4(4): 58.
7.  Poliquin V, Victory R, Vilos GA. Epidemiology, presentation, and management of retroperitoneal leiomyomata: systematic literature review and case report[J]. J Minim Invasive Gynecol, 2008, 15(2): 152-160.
8.  陳洪彬, 陽(yáng)志寧. 子宮頸巨大平滑肌瘤26例臨床分析[J]. 四川醫(yī)學(xué), 2003, 24(8): 782-783.
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11.  劉新民, 鄒淑華. 巨大闊韌帶與盆腹腔宮頸肌瘤手術(shù)[J]. 實(shí)用婦產(chǎn)科雜志, 1997, 13(6): 310.
12.  夏麗娟. 巨大宮頸肌瘤24例手術(shù)治療臨床分析[J]. 中國(guó)婦幼保健, 2007, 22(33): 4790.
13.  Steinauer J, Pritts EA, Jackson R, et al. Systematic review of mifepristone for the treatment of uterine leiomyomata[J]. Obstet Gynecol, 2004, 103(6): 1331-1336.
14.  周琦, 趙友萍, 熊曉燕. 手術(shù)治療特殊位置巨大子宮肌瘤3例[J]. 實(shí)用婦產(chǎn)科雜志, 2008, 24(3): 187-188.
  1. 1.  連利娟, 林巧稚. 婦科腫瘤學(xué)[M]. 2版. 北京: 人民衛(wèi)生出版社, 1996: 359.
  2. 2.  林巧稚. 婦科腫瘤[M]. 北京: 人民出版社, 1982: 64.
  3. 3.  沈浣. 宮頸肌瘤58例臨床分析[J]. 中國(guó)實(shí)用婦科與產(chǎn)科雜志, 1991, 15(6): 300.
  4. 4.  馮令達(dá), 邵敬於, 朱萬(wàn)里. 69例宮頸肌瘤的手術(shù)途徑及術(shù)式研究[J]. 腫瘤, 2001, 21(4): 297-299.
  5. 5.  Tiltman AJ. Leiomyomas of the uterine cervix: a study of frequency[J]. Int J Gynecol Pathol, 1998, 17(3): 231-234.
  6. 6.  曾桂英. 子宮頸部肌瘤36例分析[J]. 中華今日醫(yī)學(xué)雜志, 2004, 4(4): 58.
  7. 7.  Poliquin V, Victory R, Vilos GA. Epidemiology, presentation, and management of retroperitoneal leiomyomata: systematic literature review and case report[J]. J Minim Invasive Gynecol, 2008, 15(2): 152-160.
  8. 8.  陳洪彬, 陽(yáng)志寧. 子宮頸巨大平滑肌瘤26例臨床分析[J]. 四川醫(yī)學(xué), 2003, 24(8): 782-783.
  9. 9.  Varras M, Hadjilira P, Polyzos D, et al. Clinical considerations and sonographic findings of a large nonpedunculated primary cervical leiomyoma complicated by heavy vaginal haemorrhage: a case report and review of the literature[J]. Clin Exp Obstet Gynecol, 2003, 30(2-3): 144-146.
  10. 10.  梁小梅. 巨大宮頸肌瘤24例手術(shù)治療體會(huì)[J]. 廣西醫(yī)學(xué), 2003, 25(7): 1269-1270.
  11. 11.  劉新民, 鄒淑華. 巨大闊韌帶與盆腹腔宮頸肌瘤手術(shù)[J]. 實(shí)用婦產(chǎn)科雜志, 1997, 13(6): 310.
  12. 12.  夏麗娟. 巨大宮頸肌瘤24例手術(shù)治療臨床分析[J]. 中國(guó)婦幼保健, 2007, 22(33): 4790.
  13. 13.  Steinauer J, Pritts EA, Jackson R, et al. Systematic review of mifepristone for the treatment of uterine leiomyomata[J]. Obstet Gynecol, 2004, 103(6): 1331-1336.
  14. 14.  周琦, 趙友萍, 熊曉燕. 手術(shù)治療特殊位置巨大子宮肌瘤3例[J]. 實(shí)用婦產(chǎn)科雜志, 2008, 24(3): 187-188.