【摘要】 目的 探討甲型H1N1流感危重癥患者的搶救療效。 方法 2009年10月－2010年1月，對(duì)我院ICU收治5例甲型H1N1流感危重癥患者采用集束化治療方案進(jìn)行救治，并就患者的器官功能變化進(jìn)行評(píng)價(jià)。 結(jié)果 5例患者平均住院天數(shù)為（11.8±5.59）d，4 例存活，1例死亡。存活患者在治療過(guò)程中急性生理和既往健康 （APACHE）Ⅱ、多器官功能障礙綜合征評(píng)分（MODS）、全身性感染相關(guān)的器官衰竭評(píng)分 （SOFA）總體呈逐漸下降趨勢(shì)。死亡者APACHEⅡ、SOFA評(píng)分均呈逐漸升高趨勢(shì)。 結(jié)論 對(duì)甲型H1N1流感危重癥患者采取集束化救治療效良好。
【Abstract】 Objective To explore the effect of bundle therapy on severe patients with influenza A (H1N1). Methods Bundle therapy were used in 5 severe patients with influenza A from October 2009 to January 2010. The patients’ organ dysfunction were observed for. Results The average in-hospital duration was (11.80±5.59) days. Four patients survived and one died with the survival ratio of 80%. Acute physiology and chronic health evaluation (APACHE) II score, Multiple organ dysfunction syndrome (MODS) score and sepsis-related organ failure assessment (SOFA) score gradually decreased in 4 survived patients, while gradually increased in the died patient. Conclusion Bundle therapy is effective on patients with severe influenza A.
引用本文： 楊明全,肖國(guó)輝. 5例甲型H1N1流感危重患者救治. 華西醫(yī)學(xué), 2011, 26(7): 1022-1024. doi: 復(fù)制
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- 2. Agarwal PP, Cinti S, Kazerooni EA. Chest radiographic and CT findings in novel swine-origin influenza A (H1N1) virus(S-OlV) infection[J]. AJR Am J Roentgenol, 2009, 193(6): 1488-1493.
- 3. 朱玉春, 王建良, 劉麗華, 等. 6例重癥甲型H1N1流感的肺部CT影像分析[J]. 中國(guó)醫(yī)學(xué)影像學(xué)雜志, 2011, 19(2): 149-152.
- 4. Chowell G, Bertozzi SM, Cochero MA, et al. Severe respiratory disease concurrent with the circulation of HlN1 influenza[J]. N Engl J Med, 2009, 361(7): 674-679.
- 5. Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S, et al. Pneumonia and respiratory failure from swine-origin inf1uenza A(H1N1)in Mexico[J]. N Engl J Med, 2009, 361(7): 680-689.
- 6. 李華, 馬如存. 青海省75例重癥甲型H1N1流感患者臨床分析[J]. 中國(guó)危重病急救醫(yī)學(xué), 2010, 22(3): 164-165.
- 7. 李秀惠, 夏章, 田一梅, 等. 新型甲型H1 N1流感重癥17例臨床特征分析[J]. 環(huán)球中醫(yī)藥, 2010, 3(1): 13-17.
- 8. 寇國(guó)先, 熊鳳鳴, 韓愛(ài)華, 等. 重癥與危重甲型H1N1流感40例臨床分析[J]. 浙江臨床醫(yī)學(xué), 2011, 13(3): 262-264.