【摘要】 目的 探討尿路插管所致真菌感染患者的血漿和尿液中1，3-β-D葡聚糖檢測的臨床意義。 方法 將2009年1-5月47例尿路插管所致真菌感染患者設(shè)為試驗(yàn)組，50例正常健康體檢者設(shè)為對照組，分別檢測其血漿和尿液中1，3-β-D葡聚糖的水平。 結(jié)果 試驗(yàn)組與對照組比較，血漿及尿液中1，3-β-D葡聚糖含量差異有統(tǒng)計學(xué)意義（P lt;0.001）；試驗(yàn)組的尿液和血漿中1，3-β-D葡聚糖含量比較，有統(tǒng)計學(xué)意義（P lt;0.05），尿液中的1，3-β-D葡聚糖含量高于血漿。 結(jié)論 血漿和尿液1，3-β-D葡聚糖水平檢測可作為診斷泌尿系統(tǒng)真菌感染的可靠指標(biāo)，且尿液樣本的診斷價值高于血漿。
引用本文： 楊莉萍,曹登成. 1，3-β-D葡聚糖檢測對尿路插管所致真菌感染的診斷價值. 華西醫(yī)學(xué), 2010, 25(8): 1553-1555. doi: 復(fù)制
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| 10. | 廖經(jīng)忠, 劉文恩, 易斌, 等. 血清(1-3)-β-D-葡聚糖檢測對深部真菌感染的診斷價值[J]. 實(shí)用預(yù)防醫(yī)學(xué), 2009, 16(1): 226-228. |
- 1. 高蕾, 周新. (1, 3)-β-D葡聚糖檢測在侵襲性真菌感染中的診斷意義[J]. 中國感染與化療雜志, 2008, 8(2): 121-125.
- 2. Mennink-Kersten MA, Donnelly JP, Verweij PE. Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosis[J]. Lancet Infect Dis, 2004, 4(6): 349-357.
- 3. 孫寶云, 康云平, 滕勇, 等. 肺部真菌感染患者外周血1-3-β-D-葡聚糖水平分析[J]. 中國預(yù)防醫(yī)學(xué)雜志, 2009, 10(5): 354-355.
- 4. Pazos C, Pontón J, Del Palacio A. Contribution of (1, 3)-β-D-glucan chromogenic assay to diagnosis and therapeutic monitoring of invasive aspergillosis in neurpenic adult patients: a comparison with serial screening for circulating galactomannan[J]. J Clin Microbiol, 2005, 43(1): 299-305.
- 5. Odabasi Z, Mattiuzzi G, Estey E, et al. β-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome[J]. Clin Infect Dis, 2004, 39(2): 199-205.
- 6. Yoshida K. Recent advances of serodiagnosis for systemic fungal infections[J]. Nippon lshinkin Gakkai Zasshi, 2006, 47(3): 135-142.
- 7. Kedzierska A. (1, 3)-beta-D-glucan-a new marker for the early serodiagnosis of deep-seated fungal infections in humans[J]. Pol J Microbiol, 2007, 56(1): 3-9.
- 8. 趙勇, 王紅, 任愛民, 等. 血漿β-1, 3-D-葡聚糖對深部真菌感染診斷的研究[J]. 中國真菌學(xué)雜志, 2007, 2(4): 202-206.
- 9. 張建芳, 徐修禮, 樊新, 等. 深部真菌感染患者血漿1-3-β-D葡聚糖檢測的臨床意義[J]. 中華醫(yī)院感染學(xué)雜志, 2005, 15(3): 354-355.
- 10. 廖經(jīng)忠, 劉文恩, 易斌, 等. 血清(1-3)-β-D-葡聚糖檢測對深部真菌感染的診斷價值[J]. 實(shí)用預(yù)防醫(yī)學(xué), 2009, 16(1): 226-228.