• 成都市傳染病醫(yī)院(成都,610061);

【摘要】人工肝支持系統(tǒng)是一套以血液凈化為基礎(chǔ)的治療方法,并在緩解重型肝炎患者的病情、延長其生命、爭取肝移植時間等方面取得?,F(xiàn)就近年來國內(nèi)外非生物型人工肝的發(fā)展現(xiàn)狀及其臨床應(yīng)用作一綜述。

引用本文: 胡蓉,陳竹. 人工肝支持系統(tǒng)的臨床應(yīng)用. 華西醫(yī)學(xué), 2010, 25(8): 1571-1573. doi: 復(fù)制

1. Li LJ, Liu XL, Xu XW, et al. Comparison of plasma exchange with different membrane pore sizes in the treatment of severe viral hepatitis[J]. Ther Apher Dial, 2005, 9(5):396-401.
2. Yonekawa C, Nakae H, Tajimi K, et al. Effectiveness of combining plasma exchange with continuous hemodiafiltration in patients with postoperative Liver failure[J]. Artif Organs 2005, 29 (9):324-328.
3. 車龍, 牛殿吉, 金福東, 等. 血漿吸附治療高膽紅素血癥臨床觀察[J]. 中國危重病急救醫(yī)學(xué), 2006, 18(1):12.
4. 趙慧媛, 李榮山, 邵珊, 等. 血液灌流對IL-6、TNF-a、CRP的影響[J]. 中國血液凈化, 2005, (4)10: 566-568.
5. Pless G, Sauer I M. Bioartificial liver:current statues [J]. Transplant Proc, 2005, 37(9):3893-3895.
6. Laleman W, Wilmer A, Evenepoel P, et al. Review article:non-biological liver support in liver failure[J]. A1iment Pharmocol Ther, 2006, 23:351-363.
7. Onodera K, Sakata H, Yonekawa M, et al. Artificial liver support at present and in the future[J]. J Artif Organs, 2006, 9(1):17-28.
8. Rifai K, Ernst T, Kretschmer U, et al. Removal selectivity of Prometheus:A new extracorporeal liver support device[J]. World J Gastroenterol, 2006, 12(6):940-944.
9. 向德棟, 王宇明, 毛青, 等. 非生物人工肝對慢性重型肝炎肝功能支持效果評價[J]. 傳染病信息, 2008, 21(2):90-91.
10. 王堂明, 李玉龍, 邱波, 等. 人工肝支持系統(tǒng)治療慢性重型肝炎療效觀察[J]. 肝臟, 2008, 13(4): 320-322.
11. 鄒春毅, 魏麗艷, 李穎, 等. 人工肝支持系統(tǒng)治療重型肝病、肝衰竭的療效及影響因素分析[J]. 透析與人工器官, 2008, 19(3):1-7.
12. 劉燕, 何金秋, 鄒正宇, 等. 組合型非生物人工肝治療重型肝炎合并肝性腦病臨床研究[J]. 臨床薈萃, 2008, 23(7):495-496.
13. Pryor HI 2nd, Vacanti JV. The promise of artificial liver replacement[J]. Front Biosci 2008;13:2140-2159.
14. 王宇, 陳洋, 郭仁福, 等. HepG2細胞構(gòu)成的生物人工肝體外氨與安定的代謝能力[J]. 世界華人消化雜志, 2005, 13(5):648-652.
15. Rozga J. Liver support technology-an update[J]. Xenotransplantation, 2006, 13(5):380-389.
16. Demetriou AA, Brown RSJ, Busuttil RW, et al. Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure[J]. Ann Surg, 2004, 239(5):660-670.
17. Li J, Li LJ, Yu HY, et al. Growth and metablism of human hepatocytes on biomodified collagen poly (lactic-coglycolic acid) three-dimensional scaffold[J]. ASAIO J, 2006, 52(3):321-327.
  1. 1. Li LJ, Liu XL, Xu XW, et al. Comparison of plasma exchange with different membrane pore sizes in the treatment of severe viral hepatitis[J]. Ther Apher Dial, 2005, 9(5):396-401.
  2. 2. Yonekawa C, Nakae H, Tajimi K, et al. Effectiveness of combining plasma exchange with continuous hemodiafiltration in patients with postoperative Liver failure[J]. Artif Organs 2005, 29 (9):324-328.
  3. 3. 車龍, 牛殿吉, 金福東, 等. 血漿吸附治療高膽紅素血癥臨床觀察[J]. 中國危重病急救醫(yī)學(xué), 2006, 18(1):12.
  4. 4. 趙慧媛, 李榮山, 邵珊, 等. 血液灌流對IL-6、TNF-a、CRP的影響[J]. 中國血液凈化, 2005, (4)10: 566-568.
  5. 5. Pless G, Sauer I M. Bioartificial liver:current statues [J]. Transplant Proc, 2005, 37(9):3893-3895.
  6. 6. Laleman W, Wilmer A, Evenepoel P, et al. Review article:non-biological liver support in liver failure[J]. A1iment Pharmocol Ther, 2006, 23:351-363.
  7. 7. Onodera K, Sakata H, Yonekawa M, et al. Artificial liver support at present and in the future[J]. J Artif Organs, 2006, 9(1):17-28.
  8. 8. Rifai K, Ernst T, Kretschmer U, et al. Removal selectivity of Prometheus:A new extracorporeal liver support device[J]. World J Gastroenterol, 2006, 12(6):940-944.
  9. 9. 向德棟, 王宇明, 毛青, 等. 非生物人工肝對慢性重型肝炎肝功能支持效果評價[J]. 傳染病信息, 2008, 21(2):90-91.
  10. 10. 王堂明, 李玉龍, 邱波, 等. 人工肝支持系統(tǒng)治療慢性重型肝炎療效觀察[J]. 肝臟, 2008, 13(4): 320-322.
  11. 11. 鄒春毅, 魏麗艷, 李穎, 等. 人工肝支持系統(tǒng)治療重型肝病、肝衰竭的療效及影響因素分析[J]. 透析與人工器官, 2008, 19(3):1-7.
  12. 12. 劉燕, 何金秋, 鄒正宇, 等. 組合型非生物人工肝治療重型肝炎合并肝性腦病臨床研究[J]. 臨床薈萃, 2008, 23(7):495-496.
  13. 13. Pryor HI 2nd, Vacanti JV. The promise of artificial liver replacement[J]. Front Biosci 2008;13:2140-2159.
  14. 14. 王宇, 陳洋, 郭仁福, 等. HepG2細胞構(gòu)成的生物人工肝體外氨與安定的代謝能力[J]. 世界華人消化雜志, 2005, 13(5):648-652.
  15. 15. Rozga J. Liver support technology-an update[J]. Xenotransplantation, 2006, 13(5):380-389.
  16. 16. Demetriou AA, Brown RSJ, Busuttil RW, et al. Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure[J]. Ann Surg, 2004, 239(5):660-670.
  17. 17. Li J, Li LJ, Yu HY, et al. Growth and metablism of human hepatocytes on biomodified collagen poly (lactic-coglycolic acid) three-dimensional scaffold[J]. ASAIO J, 2006, 52(3):321-327.