• 瀘州醫(yī)學院附屬醫(yī)院 1超聲診斷科; 2 胸外科,四川瀘州 646000;

目的:應用應變率探討不同左心室構(gòu)型的原發(fā)性高血壓患者左心室長軸方向應變－應變率成像的變化,及其與EF、FS及二尖瓣血流測量評價左室功能的對照研究。方法:采用M型、二維、多普勒超聲及應變率成像技術(shù),測量左室室壁厚度、左室內(nèi)徑、EF、FS,二尖瓣血流頻譜E、A及左室平均應變ε,應變率S、e、a。結(jié)果:高血壓離心性肥厚組EF、FS明顯低于對照組,高血壓其余各組EF、FS與對照組無統(tǒng)計學差異;收縮期應變率S應變ε在五組間差異均有顯著性意義:高血壓各組較正常對照組減小(I--Ⅴ呈遞減);舒張期應變率e減低、a增高,e/a比值減小,各組間存在統(tǒng)計學差異(P lt;0.05); E/A,e/a結(jié)果大體一致。結(jié)論:應變率成像為臨床提供了一個敏感、簡便、可靠的評價原發(fā)性高血壓患者左室心肌功能的指標。

引用本文： 范英,伍長學,高玉麗. 應變率成像評價不同構(gòu)型高血壓左室功能的臨床研究. 華西醫(yī)學, 2009, 24(8): 2011-2014. doi: 復制

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  2. 2. GANAU A, DEVEREUX R B, ROMAN M J, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension[J]. J Am Coll Cardiol, 1992,19(7):1550–1558.
  3. 3. RAMZI Y KHAMIS and JAMIL MAYET. Echocardiographic assessment of left ventricular hypertrophy in elite athletes[J]. Heart, 2008, 94(10): 1254 – 1255.
  4. 4. EVA G, DANA C, GIOVANNI S,et al. Impact of left ventricular geometry on prognosis in hypertensive patients with left ventricular hypertrophy (the LIFE study)[J].Eur J Echocardiogr, 2008, 9(6):809-815.
  5. 5. GERALD D B, MANUEL C, MORTEZA G, et al. Sructure/function interface with sequential shortening of basal and apical components of the myocardial band[J]. Eur J Cardiothorac Surg, 2006, 29(Suppl 1): S75- S97.
  6. 6. SIMONE G, KITZMAN D W, CHINALI M, et al. Left ventricular concentric geometry is associated with impaired relaxation in hypertension: the HyperGEN study[J]. Eur. Heart J, 2005, 26(10): 1039 -1045.
  7. 7. WANG J W, DIRAR S K, VINAY T, et al. Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures[J]. Circulation, 2007, 115(11): 1376 -1383.