• 四川省成都市第三人民醫(yī)院心內(nèi)科,四川成都 610031;

目的:探討24 h平均脈壓(PP)對高血壓病患者左心室肥厚(LVH)的影響。方法:入選原發(fā)性高血壓病患者136 例,進(jìn)行24 h 動態(tài)血壓監(jiān)測和超聲心動圖檢查。根據(jù)24 h 平均脈壓水平各分為3組進(jìn)行比較。結(jié)果:24 h平均脈壓與年齡、左心室重量指數(shù)、動脈僵硬度指數(shù)有顯著的相關(guān)性。結(jié)論:脈壓升高是老年高血壓病患者左心室肥厚的重要危險因素。

引用本文： 吳鏡,蔡琳,王偉,唐炯,羅俊,燕純伯,余秀瓊,鄧曉奇. 脈壓對高血壓病患者左心室肥厚的影響. 華西醫(yī)學(xué), 2009, 24(8): 2125-2127. doi: 復(fù)制

1. ASMAR R. Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations[J]. Am J Hypertens,2001,14 (2):91-97.
2. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111 – 116.
3. VERDECCHIA P,SCHILLACI G,BORGIONI C,et al. Ambulartory pulse pressure: a potent predicition of total cardio vascular risk in hypertension[J]. Hypertension,1998,32 (6):983- 988.
4. 劉力生.中國高血壓防治指南[M]. 北京:人民衛(wèi)生出版社,2005: 14.
5. OTELIO SR, NICO W, GERARD CB, et al. Reliability of stroke volume to pulse pressure ratio for estimating and detecting changes in arterial compliance[J].J Hypertens,1986,4(Suppl 5):S293-S296.
6. ALDERMAN MH. A new medel of risk:implication of increasing pulse pressure and systolic blood pressure on cardiovascular disease[J]. J Hypertension,1999,17 (Suppl5):25-28.
7. BOUTOUYRIE P,BUSSY C,LACOLLY P,et al.Association between local pulse pressure,mean blood pressure and large artiry remodeling[J]. Circulation,1999,100 (13):1387.
8. KHATTAR RS,ACHARYA DU,KINSEY C,et al. Congitudinal association of ambulatory pluse pressure with left ventricular mass and vascular hypertrouy in essential hypertension[J]. J Hypertens,1997,15 (7):707-743.
9. FRANKLIN SS, GUSTIN W4T H, WONG ND, et al. Hemodynamic patterns of agerelated changes in blood pressure. The Framingham study[J]. Circulation,1997,96:308-315.
10. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111-116.
11. O’ROURKE MF, HAYWARD CS, LEHMAN ED, et al. Arterial stiffness. In:Oparil S,Weber MA, eds, Hypertension:a companion to Brenner & Rector’s Kidney[J]. Sauders,2000:134-151.
12. GELENTANO A, PALMIERI V, PALMA EN, et al.. Relations of pulse pressure and other components of blood pressure to preclinical echocardiographic abnormalities[J].J Hypertens,2002,20: 531-537.
13. JOKINIITTY JM, TUOMISTO MT, MAJAHALME SK, et al.. Pulse pressure responses to psychological tasks improve the prediction of left ventricular mass: 10 years of followup[J].J Hypertens,2003,21:789-795.
14. MULE G, NARDI E, ANDRONICO G, et al. Pul satile and steady 24 h blood pressure components as determinants of left ventricular mass in young and middleaged essential hypertensives[J]. J Hum Hypertens,2003,17:231-238.
15. RIZZO V, DI MAIO F, PETRETTO F, et al. Ambulatory pulse pressure, left ventricular hypertrophy and function in arterial hypertension[J]. Echocardiography,2004,21:11-16.
16. VERDECCHIA P, SCHILLACI G, BORGIONI C, et al. Adrerse prognostic significance of concentiric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass[J]. J Am Coll Cardiol, 1995, 25: 871-878.
17. 丁國峰, 孫運愛, 武金蓮, 等. 氨氯地平治療高血壓及逆轉(zhuǎn)左室肥厚作用的臨床研究[J]. 心血管康復(fù)醫(yī)學(xué)雜志, 2004, 13(2): 163-165.
18. BRAZ NOGUEIRA J. Regression of left ventricular hypertrophy in hypertensiondoes it reduce cardiovascular risk[J]? Rev Port Cardiol, 2005, 24 (728): 1007-1013.
19. STANTON AV. Prediction of cardiovascular damage in hypertensive patients clinic or ambulatory blood pressure[J]?J Hum Hypertens, 1999, 13(9): 81.
  1. 1. ASMAR R. Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations[J]. Am J Hypertens,2001,14 (2):91-97.
  2. 2. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111 – 116.
  3. 3. VERDECCHIA P,SCHILLACI G,BORGIONI C,et al. Ambulartory pulse pressure: a potent predicition of total cardio vascular risk in hypertension[J]. Hypertension,1998,32 (6):983- 988.
  4. 4. 劉力生.中國高血壓防治指南[M]. 北京:人民衛(wèi)生出版社,2005: 14.
  5. 5. OTELIO SR, NICO W, GERARD CB, et al. Reliability of stroke volume to pulse pressure ratio for estimating and detecting changes in arterial compliance[J].J Hypertens,1986,4(Suppl 5):S293-S296.
  6. 6. ALDERMAN MH. A new medel of risk:implication of increasing pulse pressure and systolic blood pressure on cardiovascular disease[J]. J Hypertension,1999,17 (Suppl5):25-28.
  7. 7. BOUTOUYRIE P,BUSSY C,LACOLLY P,et al.Association between local pulse pressure,mean blood pressure and large artiry remodeling[J]. Circulation,1999,100 (13):1387.
  8. 8. KHATTAR RS,ACHARYA DU,KINSEY C,et al. Congitudinal association of ambulatory pluse pressure with left ventricular mass and vascular hypertrouy in essential hypertension[J]. J Hypertens,1997,15 (7):707-743.
  9. 9. FRANKLIN SS, GUSTIN W4T H, WONG ND, et al. Hemodynamic patterns of agerelated changes in blood pressure. The Framingham study[J]. Circulation,1997,96:308-315.
  10. 10. KHATTAR. Value of ambulatory imtra arterial blood pressure monitoring in the long term prediction of left ventricular hypertophy and carotid atherosclerosis in essential hypertension[J]. J Hum Hypertens,1999,13 (2):111-116.
  11. 11. O’ROURKE MF, HAYWARD CS, LEHMAN ED, et al. Arterial stiffness. In:Oparil S,Weber MA, eds, Hypertension:a companion to Brenner & Rector’s Kidney[J]. Sauders,2000:134-151.
  12. 12. GELENTANO A, PALMIERI V, PALMA EN, et al.. Relations of pulse pressure and other components of blood pressure to preclinical echocardiographic abnormalities[J].J Hypertens,2002,20: 531-537.
  13. 13. JOKINIITTY JM, TUOMISTO MT, MAJAHALME SK, et al.. Pulse pressure responses to psychological tasks improve the prediction of left ventricular mass: 10 years of followup[J].J Hypertens,2003,21:789-795.
  14. 14. MULE G, NARDI E, ANDRONICO G, et al. Pul satile and steady 24 h blood pressure components as determinants of left ventricular mass in young and middleaged essential hypertensives[J]. J Hum Hypertens,2003,17:231-238.
  15. 15. RIZZO V, DI MAIO F, PETRETTO F, et al. Ambulatory pulse pressure, left ventricular hypertrophy and function in arterial hypertension[J]. Echocardiography,2004,21:11-16.
  16. 16. VERDECCHIA P, SCHILLACI G, BORGIONI C, et al. Adrerse prognostic significance of concentiric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass[J]. J Am Coll Cardiol, 1995, 25: 871-878.
  17. 17. 丁國峰, 孫運愛, 武金蓮, 等. 氨氯地平治療高血壓及逆轉(zhuǎn)左室肥厚作用的臨床研究[J]. 心血管康復(fù)醫(yī)學(xué)雜志, 2004, 13(2): 163-165.
  18. 18. BRAZ NOGUEIRA J. Regression of left ventricular hypertrophy in hypertensiondoes it reduce cardiovascular risk[J]? Rev Port Cardiol, 2005, 24 (728): 1007-1013.
  19. 19. STANTON AV. Prediction of cardiovascular damage in hypertensive patients clinic or ambulatory blood pressure[J]?J Hum Hypertens, 1999, 13(9): 81.