• 四川省遂寧市中心醫(yī)院腎內科,四川遂寧 629000;

目的:探討腹膜透析相關性腹膜炎的致病菌及其耐藥性。方法:回顧性分析的93例腹膜透析相關性腹膜炎的致病菌及其耐藥性。結果:34例培養(yǎng)陽性, 透出液培養(yǎng)陽性率為36.6%, 其中革蘭陽性球菌14例, 革蘭陰性桿菌17例, 真菌4例。革蘭陰性桿菌對氨芐西林的耐藥率最高,達83.3%,亞胺培南耐藥性最低,達20.0%。革蘭陽性球菌對青霉素、環(huán)丙沙星的耐藥率高,分別為81.8%、71.4%。 結論:提高腹膜透析液細菌培養(yǎng)陽性率有助于腹膜透析相關性腹膜炎的治療;在經驗用藥基礎上,應依據細菌培養(yǎng)、藥敏,選擇治療腹膜透析相關性腹膜炎的敏感、有效抗菌素,真菌性腹膜炎治療效果仍差,應盡早拔管。

引用本文： 唐勇,劉婕. 腹膜透析相關性腹膜炎致病菌的耐藥性分析. 華西醫(yī)學, 2009, 24(8): 2150-2151. doi: 復制

1. PIRAINO B, BAILIE G R, BERNARDINI J, et al. Peritoneal dialysisrelated infections recommendations: 2005 update[J]. Perit Dial Int,2005,25(2):107-131.
2. FRIED L F, BERNARDINI J, JOHNSTON J R, et al. Peritonitis influences mortality in peritoneal dialysis patients.[J]. J Am Soc Nephrol,1996,7(10):2176-2182.
3. WIGGINS K J, JOHNSON D W, CRAIG J C, et al. Treatment of peritoneal dialysisassociated peritonitis: a systematic review of randomized controlled trials.[J]. Am J Kidney Dis,2007,50(6):967-988.
4. 董捷. 關于2005年ISPD腹膜透析相關感染診治指南的幾點思考[J]. 中國血液凈化,2008(03):117-119.
5. SZETO C C, CHOW K M, KWAN B C, et al. Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive cases.[J]. Clin J Am Soc Nephrol,2007,2(2):245251.
6. PORT F K, HELD P J, NOLPH K D, et al. Risk of peritonitis and technique failure by CAPD connection technique: a national study.[J]. Kidney Int,1992,42(4):967-974.
7. 郭群英, 陳林, 陽曉, 等. 腹膜透析相關感染性腹膜炎致病菌及菌譜變化單個腹膜透析中心15年回顧分析[J]. 中華腎臟病雜志,2006(12):719-724.
8. KRISHNAN M, THODIS E, IKONOMOPOULOS D, et al. Predictors of outcome following bacterial peritonitis in peritoneal dialysis.[J]. Perit Dial Int,2002,22(5):573-581.
  1. 1. PIRAINO B, BAILIE G R, BERNARDINI J, et al. Peritoneal dialysisrelated infections recommendations: 2005 update[J]. Perit Dial Int,2005,25(2):107-131.
  2. 2. FRIED L F, BERNARDINI J, JOHNSTON J R, et al. Peritonitis influences mortality in peritoneal dialysis patients.[J]. J Am Soc Nephrol,1996,7(10):2176-2182.
  3. 3. WIGGINS K J, JOHNSON D W, CRAIG J C, et al. Treatment of peritoneal dialysisassociated peritonitis: a systematic review of randomized controlled trials.[J]. Am J Kidney Dis,2007,50(6):967-988.
  4. 4. 董捷. 關于2005年ISPD腹膜透析相關感染診治指南的幾點思考[J]. 中國血液凈化,2008(03):117-119.
  5. 5. SZETO C C, CHOW K M, KWAN B C, et al. Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive cases.[J]. Clin J Am Soc Nephrol,2007,2(2):245251.
  6. 6. PORT F K, HELD P J, NOLPH K D, et al. Risk of peritonitis and technique failure by CAPD connection technique: a national study.[J]. Kidney Int,1992,42(4):967-974.
  7. 7. 郭群英, 陳林, 陽曉, 等. 腹膜透析相關感染性腹膜炎致病菌及菌譜變化單個腹膜透析中心15年回顧分析[J]. 中華腎臟病雜志,2006(12):719-724.
  8. 8. KRISHNAN M, THODIS E, IKONOMOPOULOS D, et al. Predictors of outcome following bacterial peritonitis in peritoneal dialysis.[J]. Perit Dial Int,2002,22(5):573-581.