摘要:目的: 探討重度、極重度COPD急性加重期合并多MODS臨床特征和預(yù)后有關(guān)的危險因素。 方法 :回顧分析1999～2009年因重度、極重度COPD急性期合并多器官功能障礙而住院的患者臨床資料。 結(jié)果 :本研究共納入226例患者,平均年齡為693±52歲。呼吸系統(tǒng)功能障礙發(fā)生率最高,有200例。其次是心血管功能障礙和中樞神經(jīng)功能障礙,各102例?；颊叩牟∷缆孰S著器官功能障礙的數(shù)目增加而增加。 結(jié)論 :治療重度、極重度COPD急性加重時,在常規(guī)治療基礎(chǔ)的同時防治MODS是降低患者病死率的關(guān)鍵。
Abstract: Objective: To analyze the clinical characters and risk factors that relevant to prognosis of severe or very severe chronic obstructive pulmonary disease(COPD)exacerbation combining with multiple organ dysfunction syndrome(MODS). Methods :The clinical data of patients who was admitted to hospital for exacerbation of severe or very severe COPD combing with MODS ｉｎ 1999 to 2009 were retrospective analyzed. Results : 226 cases were analyzed in this study, the mean age of patients was 693±52 The incidence of respiratory system dysfunction was highest, which was 200 cases, and followed by the incidence of cardiovascular dysfunction and central nervous system dysfunction, which was 102 respectively. The mortality of these patients increased with the increasing number of organ dysfunction. Conclusion : Pｒｅｖｅｎｔ ａｎｄ te at MODS on the basis of conventional treatment of severe or very severe COPD exacerbation is the key factor that could reduce mortality of these patients.
引用本文： 包宇旺,羅建雄,史洪輝,胡穎. 重度、極重度COPD急性加重期合并多器官功能障礙226例臨床研究. 華西醫(yī)學(xué), 2009, 24(10): 2588-. doi: 復(fù)制