摘要:目的：觀察復(fù)方苦參注射液配合化療治療晚期胃癌的臨床療效。方法：將60例晚期胃
癌患者分為兩組,兩組均采用FOLFOX方案化療,21天為1個(gè)周期；2個(gè)周期評價(jià)效療。治療組
30例加用復(fù)方苦參注射液治療,14天為1療程,2個(gè)療程評價(jià)療效。觀察近期療效及臨床證候
變化、生存質(zhì)量及毒副反應(yīng)變化。結(jié)果:兩組近期療效比較,治療組與對照組總緩解率分別為433%和400%（P＞005）；兩組臨床證候變化比較,治療組與對照組總改善率分別為800%和600%（P＜005）；兩組生存質(zhì)量變化比較,治療組與對照組提高穩(wěn)定率分別為867%和567%（P＜005）；中位生存期分別為8個(gè)月和5個(gè)月；兩組毒副反應(yīng)比較,治療組毒副反應(yīng)明顯低于對照組（P＜005）。結(jié)論:復(fù)方苦參注射液配合化療治療晚期胃癌具有一定抗腫瘤作用,能緩解疼痛癥狀及臨床癥狀,減輕化療毒副反應(yīng),提高生活質(zhì)量,延長生存期。
Abstract: Objective: To study the effect of combination FuFang Ku Shen Zhusheye and chemotherapy for treatment of advanced gastric cancer. Methods: Sixty patients
with advanced gastric cancer were divided into two groups, all used with FOLFOX
regimen, 21 days a cycle; twocycle assessment of treatment effect. The treatme
nt group were treated with the FuFang Ku Shen Zhusheye plus treatment, a course
of treatment for 14 days, the effect were evaluated after two courses. The clini
cal symptoms and living quality, toxicity were dynamically observed. Results: Both shortterm effect of comparison, the overall response rates of the treatment group and the control group were 433% and 400% (P＞005); The rates of clinical symptoms of the treatment group and the controlgroup were 800% and 600% respectively (P＜005); the rates of increasing of living quality were respectively 867% and 567% (P＜005); the median survival time was 8 months and 5 months; the toxicity of the treatment group was significantly lower than that of the control group (P ＜005).Conclusion: Treating advanced gastric cancer by use of FuFang Ku Shen Zhusheye combination with chemotherapy is helpful to reducing the pain symptoms, promoting the clinical symptoms, reducing the chemotherapy side eff
ects, improving quality of life and prolonging the survival time.

引用本文： 黃智芬,劉俊波,黎漢忠,黃常江. 復(fù)方苦參注射液配合化療治療晚期胃癌30例臨床觀察. 華西醫(yī)學(xué), 2009, 24(11): 2883-2884. doi: 復(fù)制