• 南京大學(xué)醫(yī)學(xué)院附屬鼓樓醫(yī)院普外科(江蘇南京 210008);

目的  探討良性胸骨后甲狀腺腫經(jīng)頸入路切除的可行性與安全性并總結(jié)手術(shù)技巧。
方法  對我院2002年8月至2011年10月期間的85例良性胸骨后甲狀腺腫患者的臨床資料進(jìn)行回顧性分析。
結(jié)果  85例患者均經(jīng)頸入路行胸骨后甲狀腺腫切除,未發(fā)生圍手術(shù)期死亡及呼吸道梗阻,無大出血、氣胸、血胸及乳糜漏,未發(fā)生永久性喉返神經(jīng)損傷及永久性甲狀旁腺功能低下。3例患者術(shù)后1~3d出現(xiàn)聲音嘶啞,對癥處理后恢復(fù)正常。4例患者術(shù)后1~2d出現(xiàn)四肢末端麻木,1例患者出現(xiàn)輕度抽搐,予以靜脈及口服補(bǔ)鈣治療3~7d后癥狀緩解。術(shù)后頸部引流量(68±4.9)ml (35~220ml),2~6d(平均4.2d)拔除引流管。術(shù)后2年82例患者得到隨訪,無低鈣、低甲狀旁腺激素的病例,無聲音嘶啞及局部甲狀腺腫復(fù)發(fā)的病例,2例患者出現(xiàn)甲狀腺功能低下,給予調(diào)整口服甲狀腺素劑量后恢復(fù)正常。
結(jié)論  墜入型良性胸骨后甲狀腺腫經(jīng)頸入路切除是安全、可行的,而充分的暴露、循序漸進(jìn)的操作、尋準(zhǔn)間隙的鈍性分離和托拽結(jié)合是保證手術(shù)成功的關(guān)鍵。

引用本文: 蘇磊,桑劍鋒,姚永忠,王雪晨. 經(jīng)頸入路良性胸骨后甲狀腺腫切除的手術(shù)技巧. 中國普外基礎(chǔ)與臨床雜志, 2012, 19(8): 868-870. doi: 復(fù)制

1. 武正炎, 沈美萍. 結(jié)節(jié)性甲狀腺腫診治進(jìn)展[J]. 中國普外基礎(chǔ)與臨床雜志, 2004, 11(6):483-485.
2. 張志庸, 崔玉尚, 周易東, 等. 胸骨后甲狀腺腫的診斷和治療[J]. 中華外科雜志, 2001, 39(4):291-293.
3. Hegedüs L, Bonnema SJ. Approach to management of the patient with primary or secondary intrathoracic goiter[J]. J Clin Endocrinol Metab, 2010, 95(12):5155-5162.
4. Page C, Strunski V. Cervicothoracic goitre:an anatomical or radiological definition? Report of 223 surgical cases[J]. J Laryngol Otol, 2007, 121(11):1083-1087.
5. 馬步云, Sundar PS, 彭玉蘭, 等. 甲狀腺影像報告和數(shù)據(jù)系統(tǒng)在超聲檢查甲狀腺結(jié)節(jié)中的應(yīng)用[J]. 中國普外基礎(chǔ)與臨床雜志, 2011, 18(8):898-901.
6. Mercante G, Gabrielli E, Pedroni C, et al. CT cross-sectional imaging classification system for substernal goiter based on risk factors for an extracervical surgical approach[J]. Head Neck, 2011, 33(6):792-799.
7. 余生林, 賈磊. 胸骨后甲狀腺腫的外科治療[J]. 寧夏醫(yī)學(xué)雜志, 2010, 32(6):545-546.
8. Singh B, Lucente FE, Shaha AR. Substernal goiter:a clinical review[J]. Am J Otolaryngol, 1994, 15(6):409-416.
9. 巢琳, 鄭南翔, 陳力平. 23例胸骨后甲狀腺腫的外科治療[J]. 南京醫(yī)科大學(xué)學(xué)報(自然科學(xué)版), 2009, 29(10):1454-1455.
10. 吳躍煌, 祁永發(fā), 唐平章, 等. 胸骨后甲狀腺腫的手術(shù)徑路[J]. 中華耳鼻咽喉頭頸外科雜志, 2006, 41(7):528-531.
11. Calò PG, Tatti A, Farris S, et al. Substernal goiter:personal experience[J]. Ann Ital Chir, 2005, 76(4):331-335.
12. 石嵐, 程波, 劉春萍, 等. 胸骨后甲狀腺疾病的診斷和外科治療[J]. 中華普通外科雜志, 2006, 21(9):644-646.
13. Paliogiannis P, Scoqnamillo F, Denti S, et al. Surgical treatment of a patient with retrosternal thyroid goiter[J]. Ann Ital Chir, 2009, 80(6):429-433.
14. 程劍峰, 陳偉. 胸骨后甲狀腺腫外科手術(shù)治療體會[J]. 嶺南現(xiàn)代臨床外科雜志, 2011, 11(3):204-205.
15. 王志軍. 胸骨后結(jié)節(jié)性甲狀腺腫的診治體會[J]. 醫(yī)藥論壇雜志, 2010, 31(20):132-133.
16. Rugiu MG, Piemonte M. Surgical approach to retrosternal goitre:do we still need sternotomy?[J]. Acta Otorhinolaryngol Ital, 2009, 29(6):331-338.
17. Neves MC, Rosano M, Hojaij FC, et al. A critical analysis of 33 patients with substernal goiter surgically treated by neck incision[J]. Braz J Otorhinolaryngol, 2009, 75(2):172-176.
18. Bizakis J, Karatzanis A, Hajiioannou J, et al. Diagnosis and management of substernal goiter at the University of Crete[J]. Surg Today, 2008, 38(2):99-103.
19. 魏濤, 朱精強(qiáng). 甲狀腺手術(shù)理念進(jìn)展與新型手術(shù)器械在甲狀腺外科中的應(yīng)用[J]. 中國普外基礎(chǔ)與臨床雜志, 2011, 18(2):220-224.
20. Shin JJ, Grillo HC, Mathisen D, et al. The surgical management of goiter:Part I. Preoperative evaluation[J]. Laryngoscope, 2011, 121(1):60-67.
21. Rios A, Rodriquez JM, Balsalobre MD, et al. The value of various definitions of intrathoracic goiter for predicting intraoperative and postoperative complications[J]. Surgery, 2010, 147(2):233-238.
22. Testini M, Piccinni G, Lissidini G, et al. The lifting of substernal goitres using a Fogarty catheter[J]. Ann R Coll Surg Engl, 2005, 87(1):63-64.
23. 呂勇剛, 袁時芳, 姚青, 等. 巨大甲狀腺腫合并胸骨后病變或氣管軟化的外科處理[J]. 現(xiàn)代腫瘤醫(yī)學(xué), 2011, 19(3):452-453.
24. Raffaelli M, De Crea C, Ronti S, et al. Substernal goiters:incidence, surgical approach, and complications in a tertiary care referral center[J]. Head Neck, 2011, 33(10):1420-1425.
25. Al-Mufarrej F, Margolis M, Tempesta B, et al. Novel thoracoscopic approach to posterior mediastinal goiters:report of two cases[J]. J Cardiothorac Surg, 2008, 3:55.
  1. 1. 武正炎, 沈美萍. 結(jié)節(jié)性甲狀腺腫診治進(jìn)展[J]. 中國普外基礎(chǔ)與臨床雜志, 2004, 11(6):483-485.
  2. 2. 張志庸, 崔玉尚, 周易東, 等. 胸骨后甲狀腺腫的診斷和治療[J]. 中華外科雜志, 2001, 39(4):291-293.
  3. 3. Hegedüs L, Bonnema SJ. Approach to management of the patient with primary or secondary intrathoracic goiter[J]. J Clin Endocrinol Metab, 2010, 95(12):5155-5162.
  4. 4. Page C, Strunski V. Cervicothoracic goitre:an anatomical or radiological definition? Report of 223 surgical cases[J]. J Laryngol Otol, 2007, 121(11):1083-1087.
  5. 5. 馬步云, Sundar PS, 彭玉蘭, 等. 甲狀腺影像報告和數(shù)據(jù)系統(tǒng)在超聲檢查甲狀腺結(jié)節(jié)中的應(yīng)用[J]. 中國普外基礎(chǔ)與臨床雜志, 2011, 18(8):898-901.
  6. 6. Mercante G, Gabrielli E, Pedroni C, et al. CT cross-sectional imaging classification system for substernal goiter based on risk factors for an extracervical surgical approach[J]. Head Neck, 2011, 33(6):792-799.
  7. 7. 余生林, 賈磊. 胸骨后甲狀腺腫的外科治療[J]. 寧夏醫(yī)學(xué)雜志, 2010, 32(6):545-546.
  8. 8. Singh B, Lucente FE, Shaha AR. Substernal goiter:a clinical review[J]. Am J Otolaryngol, 1994, 15(6):409-416.
  9. 9. 巢琳, 鄭南翔, 陳力平. 23例胸骨后甲狀腺腫的外科治療[J]. 南京醫(yī)科大學(xué)學(xué)報(自然科學(xué)版), 2009, 29(10):1454-1455.
  10. 10. 吳躍煌, 祁永發(fā), 唐平章, 等. 胸骨后甲狀腺腫的手術(shù)徑路[J]. 中華耳鼻咽喉頭頸外科雜志, 2006, 41(7):528-531.
  11. 11. Calò PG, Tatti A, Farris S, et al. Substernal goiter:personal experience[J]. Ann Ital Chir, 2005, 76(4):331-335.
  12. 12. 石嵐, 程波, 劉春萍, 等. 胸骨后甲狀腺疾病的診斷和外科治療[J]. 中華普通外科雜志, 2006, 21(9):644-646.
  13. 13. Paliogiannis P, Scoqnamillo F, Denti S, et al. Surgical treatment of a patient with retrosternal thyroid goiter[J]. Ann Ital Chir, 2009, 80(6):429-433.
  14. 14. 程劍峰, 陳偉. 胸骨后甲狀腺腫外科手術(shù)治療體會[J]. 嶺南現(xiàn)代臨床外科雜志, 2011, 11(3):204-205.
  15. 15. 王志軍. 胸骨后結(jié)節(jié)性甲狀腺腫的診治體會[J]. 醫(yī)藥論壇雜志, 2010, 31(20):132-133.
  16. 16. Rugiu MG, Piemonte M. Surgical approach to retrosternal goitre:do we still need sternotomy?[J]. Acta Otorhinolaryngol Ital, 2009, 29(6):331-338.
  17. 17. Neves MC, Rosano M, Hojaij FC, et al. A critical analysis of 33 patients with substernal goiter surgically treated by neck incision[J]. Braz J Otorhinolaryngol, 2009, 75(2):172-176.
  18. 18. Bizakis J, Karatzanis A, Hajiioannou J, et al. Diagnosis and management of substernal goiter at the University of Crete[J]. Surg Today, 2008, 38(2):99-103.
  19. 19. 魏濤, 朱精強(qiáng). 甲狀腺手術(shù)理念進(jìn)展與新型手術(shù)器械在甲狀腺外科中的應(yīng)用[J]. 中國普外基礎(chǔ)與臨床雜志, 2011, 18(2):220-224.
  20. 20. Shin JJ, Grillo HC, Mathisen D, et al. The surgical management of goiter:Part I. Preoperative evaluation[J]. Laryngoscope, 2011, 121(1):60-67.
  21. 21. Rios A, Rodriquez JM, Balsalobre MD, et al. The value of various definitions of intrathoracic goiter for predicting intraoperative and postoperative complications[J]. Surgery, 2010, 147(2):233-238.
  22. 22. Testini M, Piccinni G, Lissidini G, et al. The lifting of substernal goitres using a Fogarty catheter[J]. Ann R Coll Surg Engl, 2005, 87(1):63-64.
  23. 23. 呂勇剛, 袁時芳, 姚青, 等. 巨大甲狀腺腫合并胸骨后病變或氣管軟化的外科處理[J]. 現(xiàn)代腫瘤醫(yī)學(xué), 2011, 19(3):452-453.
  24. 24. Raffaelli M, De Crea C, Ronti S, et al. Substernal goiters:incidence, surgical approach, and complications in a tertiary care referral center[J]. Head Neck, 2011, 33(10):1420-1425.
  25. 25. Al-Mufarrej F, Margolis M, Tempesta B, et al. Novel thoracoscopic approach to posterior mediastinal goiters:report of two cases[J]. J Cardiothorac Surg, 2008, 3:55.