• 南京醫(yī)科大學(xué)附屬常州第二人民醫(yī)院普外科(江蘇常州 213000);

目的  總結(jié)保留皮膚乳腺癌改良根治術(shù)后即時(shí)乳房再造方法的治療體會(huì)。
方法  筆者所在醫(yī)院2008年5月至2011年12月期間對(duì)10例早期乳腺癌患者行保留大部分皮膚的改良根治術(shù),同時(shí)應(yīng)用下腹部腹直肌帶蒂肌皮瓣(TRAM)行即時(shí)乳房再造,就該10例患者的臨床資料進(jìn)行回顧性分析。
結(jié)果  10例患者中1例TRAM皮瓣部分壞死,1例乳頭部分壞死,1例再造乳房乳尾部脂肪部分壞死伴腋下傷口感染;無(wú)腹壁切口疝發(fā)生,無(wú)全部TRAM皮瓣壞死病例。術(shù)后患者對(duì)再造乳房形態(tài)評(píng)價(jià)非常滿意5例,比較滿意4例,不滿意1例。
結(jié)論  保留皮膚的乳腺癌改良根治術(shù)后即時(shí)TRAM皮瓣乳房再造方法的切口小,再造乳房形態(tài)好,是一種安全有效的治療早期乳腺癌患者的方法。

引用本文: 高海燕,朱玉蘭,林維佳. 10例保留皮膚的乳腺癌改良根治術(shù)后即時(shí)TRAM皮瓣乳房再造體會(huì). 中國(guó)普外基礎(chǔ)與臨床雜志, 2012, 19(9): 962-966. doi: 復(fù)制

1. Hartrampf CR, Scheflan M, Black PW. Breast reconstruction with a transverse abdominal island flap[J]. Plast Reconstr Surg, 1982, 69(2):216-225.
2. Gui GP, Kadayaprath G, Tan SM, et al. Evaluation of outcome after immediate breast reconstruction:prospective comparison of four methods[J]. Plast Reconstr Surg, 2005, 115(7):1916-1926.
3. Ziswiler-Gietz J, Makrodimou M, Harder Y, et al. Outcome analysis of breast reconstruction with free transverse rectus abdominis musculocutaneous (TRAM) flaps[J]. Swiss Med Wkly, 2008, 138(7-8):114-120.
4. 張學(xué)慧, 尹健, 張如明, 等. 女性乳腺癌保留胸大肌術(shù)后Ⅰ期乳房再造[J]. 中國(guó)腫瘤臨床, 2002, 29(7):495-497.
5. Chun YS, Sinha I, Turko A, et al. Outcomes and patient satisfaction following breast reconstruction with bilateral pedicled TRAM flaps in 105 consecutive patients[J]. Plast Reconstr Surg, 2010, 125(1):1-9.
6. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2006[J]. CA Cancer J Clin, 2006, 56(2):106-130.
7. Kronowitz SJ, Hunt KK, Kuerer HM, et al. Delayed-immediate breast reconstruction[J]. Plast Reconstr Surg, 2004, 113 (6):1617-1628.
8. 宣立學(xué), 穆蘭花, 張保寧. 整形外科技術(shù)在乳腺癌治療中的應(yīng)用[J]. 中國(guó)實(shí)用外科雜志, 2006, 26(4):306-308.
9. Chagpar A, Langstein HN, Kronowitz SJ, et al. Treatment and outcome of patients with chest wall recurrence after mastectomy and breast reconstruction[J]. Am J Surg, 2004, 187(2):164-169.
10. Sandelin K, Wickman M, Billgren AM. Oncological outcome after immediate breast reconstruction for invasive breast cancer:a long-term study[J]. Breast, 2004, 13(3):210-218.
11. Cunnick GH, Mokbel K. Skin-sparing mastectomy[J]. Am J Surg, 2004, 188(1):78-84.
12. 黃曉輝, 陳凜, 石懷銀. 早期乳腺癌保留皮膚的保乳手術(shù)安全性研究[J]. 解放軍醫(yī)學(xué)雜志, 2007, 32(3):258-259.
13. Ho CM, Mak CK, Lau Y, et al. Skin involvement in invasive breast carcinoma:safety of skin-sparing mastectomy[J]. Ann Surg Oncol, 2003, 10(2):102-107.
14. Toth BA, Forley BG, Calabria R. Retrospective study of the skin-sparing mastectomy in breast reconstruction[J]. PlastReconstr Surg, 1999, 104(1):77-84.
15. Kissin MW, Kark AE. Nipple preservation during mastectomy[J]. Br J Surg, 1987, 74(1):58-61.
16. 曾健, 陸云飛, 林進(jìn)令. 保留皮膚或保留乳頭、乳暈的乳腺癌改良根治術(shù)后擴(kuò)展型背闊肌肌皮瓣即時(shí)乳房再造[J]. 中國(guó)綜合臨床, 2005, 21(10):897-899.
17. 王圣應(yīng), 魯智, 程新德, 等. 早期乳腺癌保留乳頭乳暈的復(fù)合體的改良根治術(shù)——Ⅰ期腹直肌肌皮瓣重建乳房[J]. 癌癥, 2004, 23(1):56-59.
18. 高德宗, 孫靖中, 尹群生, 等. 女性乳房手術(shù)預(yù)防乳頭乳暈壞死的血供研究[J]. 中國(guó)普通外科雜志, 2005, 14(4):269-272.
19. Slavin SA, Schnitt SJ, Duda RB, et al. Skin-sparing mastectomy and immediate reconstruction:oncologic risks and aesthetic results in patients with early-stage breast cancer[J]. PlastReconstr Surg, 1998, 102(1):49-62.
20. Soong IS, Yau TK, Ho CM, et al. Post-mastectomy radiotherapy after immediate autologous breast reconstruction in primary treatment of breast cancers[J]. Clin Oncol, 2004, 16(4):283-289.
21. 王仲照. 即刻乳房再造在乳腺癌治療中的應(yīng)用[J]. 癌癥進(jìn)展, 2005, 3(2):144-150.
22. 薛秀麗, 邱志麗, 鄒小明. 乳腺癌改良根治術(shù)后Ⅱ期應(yīng)用腹直肌皮瓣重建乳房再造1例[J]. 哈爾濱醫(yī)科大學(xué)學(xué)報(bào), 2007, 41(5):516-517.
23. 張立成. 乳腺癌術(shù)后乳房再造的進(jìn)展[J]. 實(shí)用全科醫(yī)學(xué), 2007, 5(11):1010-1011.
24. 湯學(xué)良, 鄒天寧, 陳德滇, 等. 乳腺癌改良根治術(shù)后自體肌皮瓣乳房重建21例[J]. 腫瘤學(xué)雜志, 2002, 8(6):354..
25. Mizgala CL, Hartrampf CR Jr, Bennett GK. Assessment of the abdominal wall after pedicled TRAM flap surgery:5- to 7-year follow-up of 150 consecutive patients[J]. Plast Reconstr Surg, 1994, 93(5):988-1004.
  1. 1. Hartrampf CR, Scheflan M, Black PW. Breast reconstruction with a transverse abdominal island flap[J]. Plast Reconstr Surg, 1982, 69(2):216-225.
  2. 2. Gui GP, Kadayaprath G, Tan SM, et al. Evaluation of outcome after immediate breast reconstruction:prospective comparison of four methods[J]. Plast Reconstr Surg, 2005, 115(7):1916-1926.
  3. 3. Ziswiler-Gietz J, Makrodimou M, Harder Y, et al. Outcome analysis of breast reconstruction with free transverse rectus abdominis musculocutaneous (TRAM) flaps[J]. Swiss Med Wkly, 2008, 138(7-8):114-120.
  4. 4. 張學(xué)慧, 尹健, 張如明, 等. 女性乳腺癌保留胸大肌術(shù)后Ⅰ期乳房再造[J]. 中國(guó)腫瘤臨床, 2002, 29(7):495-497.
  5. 5. Chun YS, Sinha I, Turko A, et al. Outcomes and patient satisfaction following breast reconstruction with bilateral pedicled TRAM flaps in 105 consecutive patients[J]. Plast Reconstr Surg, 2010, 125(1):1-9.
  6. 6. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2006[J]. CA Cancer J Clin, 2006, 56(2):106-130.
  7. 7. Kronowitz SJ, Hunt KK, Kuerer HM, et al. Delayed-immediate breast reconstruction[J]. Plast Reconstr Surg, 2004, 113 (6):1617-1628.
  8. 8. 宣立學(xué), 穆蘭花, 張保寧. 整形外科技術(shù)在乳腺癌治療中的應(yīng)用[J]. 中國(guó)實(shí)用外科雜志, 2006, 26(4):306-308.
  9. 9. Chagpar A, Langstein HN, Kronowitz SJ, et al. Treatment and outcome of patients with chest wall recurrence after mastectomy and breast reconstruction[J]. Am J Surg, 2004, 187(2):164-169.
  10. 10. Sandelin K, Wickman M, Billgren AM. Oncological outcome after immediate breast reconstruction for invasive breast cancer:a long-term study[J]. Breast, 2004, 13(3):210-218.
  11. 11. Cunnick GH, Mokbel K. Skin-sparing mastectomy[J]. Am J Surg, 2004, 188(1):78-84.
  12. 12. 黃曉輝, 陳凜, 石懷銀. 早期乳腺癌保留皮膚的保乳手術(shù)安全性研究[J]. 解放軍醫(yī)學(xué)雜志, 2007, 32(3):258-259.
  13. 13. Ho CM, Mak CK, Lau Y, et al. Skin involvement in invasive breast carcinoma:safety of skin-sparing mastectomy[J]. Ann Surg Oncol, 2003, 10(2):102-107.
  14. 14. Toth BA, Forley BG, Calabria R. Retrospective study of the skin-sparing mastectomy in breast reconstruction[J]. PlastReconstr Surg, 1999, 104(1):77-84.
  15. 15. Kissin MW, Kark AE. Nipple preservation during mastectomy[J]. Br J Surg, 1987, 74(1):58-61.
  16. 16. 曾健, 陸云飛, 林進(jìn)令. 保留皮膚或保留乳頭、乳暈的乳腺癌改良根治術(shù)后擴(kuò)展型背闊肌肌皮瓣即時(shí)乳房再造[J]. 中國(guó)綜合臨床, 2005, 21(10):897-899.
  17. 17. 王圣應(yīng), 魯智, 程新德, 等. 早期乳腺癌保留乳頭乳暈的復(fù)合體的改良根治術(shù)——Ⅰ期腹直肌肌皮瓣重建乳房[J]. 癌癥, 2004, 23(1):56-59.
  18. 18. 高德宗, 孫靖中, 尹群生, 等. 女性乳房手術(shù)預(yù)防乳頭乳暈壞死的血供研究[J]. 中國(guó)普通外科雜志, 2005, 14(4):269-272.
  19. 19. Slavin SA, Schnitt SJ, Duda RB, et al. Skin-sparing mastectomy and immediate reconstruction:oncologic risks and aesthetic results in patients with early-stage breast cancer[J]. PlastReconstr Surg, 1998, 102(1):49-62.
  20. 20. Soong IS, Yau TK, Ho CM, et al. Post-mastectomy radiotherapy after immediate autologous breast reconstruction in primary treatment of breast cancers[J]. Clin Oncol, 2004, 16(4):283-289.
  21. 21. 王仲照. 即刻乳房再造在乳腺癌治療中的應(yīng)用[J]. 癌癥進(jìn)展, 2005, 3(2):144-150.
  22. 22. 薛秀麗, 邱志麗, 鄒小明. 乳腺癌改良根治術(shù)后Ⅱ期應(yīng)用腹直肌皮瓣重建乳房再造1例[J]. 哈爾濱醫(yī)科大學(xué)學(xué)報(bào), 2007, 41(5):516-517.
  23. 23. 張立成. 乳腺癌術(shù)后乳房再造的進(jìn)展[J]. 實(shí)用全科醫(yī)學(xué), 2007, 5(11):1010-1011.
  24. 24. 湯學(xué)良, 鄒天寧, 陳德滇, 等. 乳腺癌改良根治術(shù)后自體肌皮瓣乳房重建21例[J]. 腫瘤學(xué)雜志, 2002, 8(6):354..
  25. 25. Mizgala CL, Hartrampf CR Jr, Bennett GK. Assessment of the abdominal wall after pedicled TRAM flap surgery:5- to 7-year follow-up of 150 consecutive patients[J]. Plast Reconstr Surg, 1994, 93(5):988-1004.