• 中國醫(yī)科大學(xué)附屬盛京醫(yī)院肝膽脾外科病房（遼寧沈陽 110004）;

目的總結(jié)老年結(jié)直腸癌肝轉(zhuǎn)移（CRCLM）治療的現(xiàn)狀，探討老年CRCLM治療的方法和原則。方法復(fù)習(xí)國內(nèi)、外近年來有關(guān)老年CRCLM治療的相關(guān)文獻(xiàn)并作綜述。結(jié)果結(jié)直腸癌是消化系統(tǒng)最常見的惡性腫瘤，而最常見的轉(zhuǎn)移部位是肝臟。近年來，老年結(jié)直腸癌發(fā)病率逐漸升高。雖然同年輕患者比較，老年CRCLM患者的身體狀態(tài)和生理機(jī)能較差，但只要選取合適的病例，同樣可以獲得與年輕患者相似的治療效果。目前，對于可切除的CRCLM患者，惟一可能治愈的手段仍然是外科手術(shù)治療; 而化療和分子靶向藥物治療的最新進(jìn)展，也讓更多的老年患者生存獲益。對于不可切除的CRCLM病灶尚可結(jié)合其他肝臟導(dǎo)向的局部治療方法，如局部化療、消融治療等。結(jié)論根據(jù)CRCLM的發(fā)病特點(diǎn)和老年患者的自身特點(diǎn)，采用多學(xué)科協(xié)作模式下的個體化治療模式，可進(jìn)一步提高老年CRCLM患者的綜合治療效果。

引用本文： 賈昌俊,戴朝六. 老年結(jié)直腸癌肝轉(zhuǎn)移的治療. 中國普外基礎(chǔ)與臨床雜志, 2011, 18(5): 485-493. doi: 復(fù)制

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