• 四川大學華西醫(yī)院放射科(四川成都 610041);

目的探討鈣化在非腫塊型乳腺腫瘤X線診斷中的意義，提高對非腫塊型乳腺良、惡性腫瘤的鑒別診斷水平。方法回顧性分析2008年11月至2011年3月期間四川大學華西醫(yī)院經病理檢查證實的X線片未見腫塊的90例乳腺腫瘤患者的臨床資料，其中乳腺良性腫瘤55例，乳腺癌35例，觀察并記錄鈣化的形態(tài)、分布、總數(shù)、位置及乳腺局限性不對稱致密。結果①乳腺良性疾病鈣化形態(tài)多粗大(31例)，多以散在分布為主(35例)，且鈣化總數(shù)較少，較少伴有乳腺局限性不對稱致密影(7例),較少伴有同側腋窩淋巴結的改變(2例)。②乳腺癌的鈣化多以細砂樣鈣化為主(32例)，顆粒細小，但鈣化大小不一致，形態(tài)各異，其鈣化的分布多呈簇樣分布(24例)，且惡性鈣化的總數(shù)較多，多伴有乳腺局限性不對稱致密影(24例)，伴有腋窩淋巴結改變(10例)。兩者鈣化的形態(tài)、分布及總數(shù)的差異均有統(tǒng)計學意義(P lt;0.05)。結論良、惡性乳腺腫瘤的鈣化各有特征，在早期乳腺腫瘤的鑒別診斷中有著重要的臨床意義。

引用本文： 羅藝,陳冬冬,李學明,余建群. 鈣化在不伴腫塊乳腺腫瘤中的表現(xiàn)特點分析. 中國普外基礎與臨床雜志, 2011, 18(9): 1007-1010. doi: 復制

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2. 汪登斌, 譚令, 江浩, 等. 乳腺癌MRI研究 [J]. 中國醫(yī)學計算機成像雜志, 2002, 8(1): 2327.
3. Jemal A, Clegg LX, Ward E, et al. Annual report to the nation on the status of cancer, 19752001, with a special feature regarding survival [J]. Cancer, 2004, 101(1): 327.
4. 周景瑋, 陳克敏, 劉林祥, 等. 乳腺疾病的MRI與鉬鈀診斷 [J]. 現(xiàn)代醫(yī)用影像學, 2006, 15(6): 280282.
5. Apantaku LM. Breast cancer diagnosis and screening [J]. Am Fam Physician, 2000, 62: 596602, 605606.
6. Winchester DP, Jeske JM, Goldschmidt RA. The diagnosis and management of ductal carcinoma insitu of the breast [J]. CA Cancer J Clin, 2000, 50(3): 184200.
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8. 陳佩珍. 乳腺癌的早期診斷 [J]. 普外基礎與臨床雜志, 1996, 3(2): 106107.
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10. De Lafontan B, DauresJP, Salicru B, et al. Isolated clustered microcalcifications: diagnostic value of mammography-series of 400 cases with surgical verification [J]. Radiology, 1994, 190(2): 479483.
11. Tabár L, Dean PB. Mammography and breast cancer: the new era [J]. Int J Gynaecol Obstet, 2003, 82(3): 319326.
12. 顧雅佳, 王玖華, 涂小予, 等. 乳腺導管原位癌的鉬靶X線表現(xiàn)與病理對照研究 [J]. 中華放射學雜志, 2002, 36(3): 240244.
13. Winchester DP, Jeske JM, Goldschmidt RA. The diagnosis and management of ductal carcinoma insitu of the breast [J]. CA Cancer J Clin, 2000, 50(3): 184200.
14. Feig SA, Galkin BM, Muir HD. Evaluation of breast microcalcifications by means of optically magnified tissue specimen radiographs [J]. Recent Results Cancer Res, 1987, 105: 111123.
15. Sickles EA. Breast calcifications: mammographic evaluation [J]. Radiology, 1986, 160(2): 289293.
16. Rangayyana RM, Ayresa FJ, Leo Desautels JE. A review of computeraided diagnosis of breast cancer: Toward the detection of subtle signs [J]. J Franklin Institute, 2007, 344(34): 312348.
17. Feig SA, D’Orsi CJ, Hendrick RE, et al. American College of Radiology guidelines for breast cancer screening [J]. AJR Am J Roentgenol, 1998, 171(1): 2933.
18. 呂青, 劉偉, 寧芳. 臨床容易誤診的乳腺良性疾病分析 [J]. 中國普外基礎與臨床雜志, 2001, 8(1): 5253.
19. Woodward WA, Strom EA, Tucker SL, et al. Changes in the 2003 American Joint Committee on Cancer staging for breast cancer dramatically affect stagespecific survival [J]. J Clin Oncol, 2003, 21(17): 32443248.
20. 陳翔, 王水. 乳腺癌前哨淋巴結活檢研究現(xiàn)狀及發(fā)展 [J]. 中國普外基礎與臨床雜志, 2011, 18(1): 98102.
  1. 1. Canadian Cancer Statistics 2011 [Z]. Canadian Cancer Society’s Steering Committee on Cancer Statistics. Toronto: Canadian Cancer Society, 2011.
  2. 2. 汪登斌, 譚令, 江浩, 等. 乳腺癌MRI研究 [J]. 中國醫(yī)學計算機成像雜志, 2002, 8(1): 2327.
  3. 3. Jemal A, Clegg LX, Ward E, et al. Annual report to the nation on the status of cancer, 19752001, with a special feature regarding survival [J]. Cancer, 2004, 101(1): 327.
  4. 4. 周景瑋, 陳克敏, 劉林祥, 等. 乳腺疾病的MRI與鉬鈀診斷 [J]. 現(xiàn)代醫(yī)用影像學, 2006, 15(6): 280282.
  5. 5. Apantaku LM. Breast cancer diagnosis and screening [J]. Am Fam Physician, 2000, 62: 596602, 605606.
  6. 6. Winchester DP, Jeske JM, Goldschmidt RA. The diagnosis and management of ductal carcinoma insitu of the breast [J]. CA Cancer J Clin, 2000, 50(3): 184200.
  7. 7. 鮑潤賢. 中國影像醫(yī)學·乳腺卷 [M]. 北京: 人民衛(wèi)生出版社, 2002: 6880.
  8. 8. 陳佩珍. 乳腺癌的早期診斷 [J]. 普外基礎與臨床雜志, 1996, 3(2): 106107.
  9. 9. 何子元, 火樹堯, 徐開野. 早期乳腺癌的X線表現(xiàn)(附40例報告) [J]. 臨床放射學雜志, 2001, 20(1): 1113.
  10. 10. De Lafontan B, DauresJP, Salicru B, et al. Isolated clustered microcalcifications: diagnostic value of mammography-series of 400 cases with surgical verification [J]. Radiology, 1994, 190(2): 479483.
  11. 11. Tabár L, Dean PB. Mammography and breast cancer: the new era [J]. Int J Gynaecol Obstet, 2003, 82(3): 319326.
  12. 12. 顧雅佳, 王玖華, 涂小予, 等. 乳腺導管原位癌的鉬靶X線表現(xiàn)與病理對照研究 [J]. 中華放射學雜志, 2002, 36(3): 240244.
  13. 13. Winchester DP, Jeske JM, Goldschmidt RA. The diagnosis and management of ductal carcinoma insitu of the breast [J]. CA Cancer J Clin, 2000, 50(3): 184200.
  14. 14. Feig SA, Galkin BM, Muir HD. Evaluation of breast microcalcifications by means of optically magnified tissue specimen radiographs [J]. Recent Results Cancer Res, 1987, 105: 111123.
  15. 15. Sickles EA. Breast calcifications: mammographic evaluation [J]. Radiology, 1986, 160(2): 289293.
  16. 16. Rangayyana RM, Ayresa FJ, Leo Desautels JE. A review of computeraided diagnosis of breast cancer: Toward the detection of subtle signs [J]. J Franklin Institute, 2007, 344(34): 312348.
  17. 17. Feig SA, D’Orsi CJ, Hendrick RE, et al. American College of Radiology guidelines for breast cancer screening [J]. AJR Am J Roentgenol, 1998, 171(1): 2933.
  18. 18. 呂青, 劉偉, 寧芳. 臨床容易誤診的乳腺良性疾病分析 [J]. 中國普外基礎與臨床雜志, 2001, 8(1): 5253.
  19. 19. Woodward WA, Strom EA, Tucker SL, et al. Changes in the 2003 American Joint Committee on Cancer staging for breast cancer dramatically affect stagespecific survival [J]. J Clin Oncol, 2003, 21(17): 32443248.
  20. 20. 陳翔, 王水. 乳腺癌前哨淋巴結活檢研究現(xiàn)狀及發(fā)展 [J]. 中國普外基礎與臨床雜志, 2011, 18(1): 98102.