• 1.重慶市第九人民醫(yī)院（重慶 400700）;;
  • 2.第三軍醫(yī)大學(xué)西南醫(yī)院全軍肝膽外科研究所（重慶 400038）;;
  • 通訊作者： 陳平;

目的探討胰十二指腸切除術(shù)后并發(fā)深部真菌感染的相關(guān)因素，為預(yù)防術(shù)后深部真菌感染提供理論依據(jù)。
方法對1995年1月至2005年1月期間我院562例行胰十二指腸切除術(shù)患者的相關(guān)資料進(jìn)行單因素和非條件Logistic回歸分析。
結(jié)果 ①562例中有78例患者術(shù)后并發(fā)深部真菌感染，感染率為13.9%； 共檢出真菌88株，其中白色念珠菌59株(67.0%)，光滑念珠菌10株(11.4%),近平滑念珠菌7株(8.0%)，熱帶念珠菌5株(5.7%)，曲霉菌4株(4.5%)，其他3株 (3.4%)。常見感染部位前3位是消化道66.7%(52/78)，呼吸道21.8%(17/78)，腹腔10.3%(8/78)。②本組病例中發(fā)生感染組與未感染組在術(shù)后發(fā)生的胰瘺、膽瘺、腹腔感染等并發(fā)癥，長期使用抗生素，長時(shí)間腸外營養(yǎng)等方面差異具有統(tǒng)計(jì)學(xué)意義（P lt;0.05）。結(jié)論①胰十二指腸切除術(shù)后深部真菌感染最常見的部位和病原菌分別是腸道和白色念珠菌。②胰瘺、膽瘺、腹腔感染等并發(fā)癥，長期使用抗生素，長時(shí)間腸外營養(yǎng)等方面是胰十二指腸切除術(shù)后并發(fā)深部真菌感染的最常見危險(xiǎn)因素； 減少各種危險(xiǎn)因素有利于預(yù)防深部真菌感染。

引用本文： 段世剛,陳平,李穎,丁紀(jì)明,張林. 胰十二指腸切除術(shù)后并發(fā)深部真菌感染的相關(guān)因素分析. 中國普外基礎(chǔ)與臨床雜志, 2006, 13(3): 317-320. doi: 復(fù)制

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