目的 探討p16蛋白在乳腺癌中的表達及其臨床意義。
方法 采用LSAB免疫組化法對107例乳腺癌標本進行p16蛋白的檢測。
結果 p16蛋白陽性率為40.19%(43/107)，生存時間≤5年，＞10年p16蛋白陽性率分別為8.00%和75.68%，p16蛋白表達陽性者生存時間明顯長于陰性者。
結論 p16蛋白的檢測是判斷乳腺癌預后的重要因素。
引用本文： 楊金巧,周蕾蕾,趙俊玲. p16蛋白在乳腺癌中的表達及其臨床意義. 中國普外基礎與臨床雜志, 2000, 7(5): 297-298. doi: 復制
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