【摘要】 目的 探討生理鈣透析液對(duì)持續(xù)性不臥床腹膜透析（CAPD）患者鈣磷代謝的影響?！》椒ā』仡櫺苑治?008年1月-2009年12月腹膜透析患者的鈣磷指標(biāo)，資料齊全的患者中使用鈣濃度為1.25 mmol/L的腹膜透析液（生理鈣組）的患者有30例，使用鈣濃度為1.75 mmol/L的透析液（標(biāo)準(zhǔn)鈣組）患者30例。對(duì)兩組患者鈣磷代謝指標(biāo)進(jìn)行比較?！〗Y(jié)果 治療前后兩組的血磷、鈣磷乘積和全段甲狀旁腺素差異均無(wú)統(tǒng)計(jì)學(xué)意義（Pgt;0.05）；治療后標(biāo)準(zhǔn)鈣組血鈣較前升高，差異有統(tǒng)計(jì)學(xué)意義（Plt;0.05），而生理鈣組治療前后血鈣差異無(wú)統(tǒng)計(jì)學(xué)意義（Pgt;0.05）。 結(jié)論 不同含鈣濃度腹膜透析液對(duì)機(jī)體鈣磷代謝的影響是不同的，在高鈣、高磷、低轉(zhuǎn)運(yùn)骨病的腹膜透析患者中使用鈣濃度為1.25 mmol/L的生理鈣透析液減輕了鈣負(fù)荷，為臨床醫(yī)生使用含鈣磷結(jié)合劑提供了治療空間?！続bstract】 Objective To investigate the effects of physiological calcium dialysate on the calcium and phosphorus metabolism in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Methods We retrospectively analyzed the clinical data of 60 patients having undergone CAPD in West China Hospital of Sichuan University between January 2008 and December 2009. The patients were divided into two groups with 30 in each by calcium concentration of the dialysate: the physiological calcium dialysate group (1.25 mmol/L) and the standard calcium dialysate group (1.75 mmol/L). The metabolism indexes of calcium and phosphorus for the two group of patients were compared. Results Levels of Serum phosphate, calcium-phosphate product and immoreactive parathyroid hormone (iPTH) of all the patients in both groups before and after treatment showed no significant differences (Pgt;0.05). Serum calcium increased significantly in patients treated with standard calcium dialysate (Plt;0.05), while it did not change significantly in patients treated with physiological calcium dialysate (Pgt;0.05). Conclusions Dialysate with different concentrations of calcium provides different influence on the metabolism of calcium and phosphorus. Changing calcium concentration to 1.25 mmol/L in the dialysate can lower the calcium load for patients with hypercalcium and/or hyperphosphate with low bone turnover, providing treatment space for clinical doctors to use binders containing both calcium and phosphorus.