【摘要】 目的 了解中藥千里光對(duì)金黃色葡萄球菌的抗菌作用，為治療金黃色葡萄球菌感染提供依據(jù)。 方法 將金黃色葡萄球菌在固體培養(yǎng)基上傳代培養(yǎng)后收集菌株，以一定濃度（菌落濃度為 3億/mL）用于腹腔注射。提取千里光水煎劑（2 g/mL）， 以其用于對(duì)小白鼠體內(nèi)抗菌實(shí)驗(yàn)。 結(jié)果 灌胃千里光水煎劑的實(shí)驗(yàn)組死亡率顯著降低。 結(jié)論 中藥千里光對(duì)金黃色葡萄球菌有一定的抑制效果。【Abstract】 Objective To evaluate the antibacterial effect of traditional Chinese medicine Senecio against staphylococcus aureus, and to provide a experimental basis for the infectious treatment of staphylococcus aureus. Methods Staphylococcus aureus were cultured in solid medium and collected after uploading strains of a certain concentration (with the concentration of 300 million colonies/mL) for intraperitoneal injection. Senecio decoction extraction (2 g/mL) was used for mice in vivo antibacterial tests. Results The mortality rate in the experimental group with stomach perfusion of the Senecio water decoction decreased significantly. Conclusion The traditional Chinese medicine Senecio has a certain suppressive effect on staphylococcus aureus.