【摘要】 目的 探討微創(chuàng)經皮腎鏡碎石術后并發(fā)感染性休克的原因和防治措施?!》椒ā』仡櫺苑治?005年1月-2010年12月5例經皮腎鏡術300例,其中術后并發(fā)感染性休克5例的臨床資料。男1例,女4例,均表現為術后2~8 h內出現寒戰(zhàn)、高熱、煩燥不安,血壓降至80/50 mm Hg(1 mm Hg=0.133 kPa)以下,心率超過120次/min。所有患者均行抗感染和抗休克治療。 結果 所有患者均在72 h內停用升壓藥,1周內體溫及血常規(guī)恢復正常,術后15 d治愈出院。 結論 感染性休克是微創(chuàng)經皮腎鏡碎石術嚴重的并發(fā)癥之一,術前有效抗感染、術中低壓灌注、術后加強生命體征的監(jiān)測、早期發(fā)現并合理處理,可有效防治感染性休克的發(fā)生?!続bstract】 Objective To explore the etiology and treatment of septic shock after percutaneous nephrolithotomy. Methods From Janurary 2005 to December 2010, the clinical data of five patients with septic shock after percutaneous nephrolithotomy in our hospital were retrospectively analyzed. The patients, including one male and four females, had chillness and high temperature after the nephrolithotomy. The blood pressure decreased to under 80/50 mm Hg (1 mm Hg=0.133 kPa), and the heart rate was more than 120 per minute. All patients underwent anti-shock and anti-infection therapies rapidly. Results Five patients were cured in the end, their temperature and blood routine tests returned to normal within one week. Conclusions Septic shock is one of the serious complications after percutaneous nephrolithotomy. Effective preoperative preparation, low pressure irrigation during operation, early diagnosis and treatment postoperatively are the effective ways to prevent the septic shock.
目的 為1例疑診細菌性肝膿腫患者制定合理的外科治療方案。方法 針對患者的臨床問題,以肝膿腫、開腹引流和腹腔鏡等MeSH主題詞和自由詞,計算機檢索 Cochrane 圖書館(2007 年第4 期)、MEDLINE(1996~2008.1)、ACP Journal Club(1991.1~2008.1)和中國期刊全文數據庫(1994~2008.1),查找相關的系統(tǒng)評價、隨機對照試驗和臨床回顧性研究等,并對所獲證據進行質量評價。 結果 我們沒有檢索到關于腹腔鏡引流與開腹引流對比治療肝膿腫的系統(tǒng)評價和大樣本隨機對照試驗,因此選擇了與臨床問題密切相關的4 篇回顧性臨床研究。其結果提示腹腔鏡下引流治療肝膿腫安全有效,具有手術時間短、創(chuàng)傷小、恢復快、費用低、并發(fā)癥少等優(yōu)點,是開腹手術的理想替代術式。但因病例數有限,還需要高質量、大規(guī)模臨床隨機對照試驗來證實,因此我們結合醫(yī)生經驗和患者意愿,對該患者未采用腹腔鏡引流治療,而是實施開腹引流手術,最終患者痊愈出院。結論 現有的4篇回顧性研究雖顯示腹腔鏡對肝膿腫患者安全有效,但患者例數有限,尚需高質量、大樣本的隨機對照試驗證實。