摘要：目的：探討血小板動態(tài)變化與新生兒重癥肺炎之間的關(guān)系。方法：測定40例新生兒重癥肺炎患兒急性期（3天）及恢復(fù)期（10天）的血小板計數(shù)（platelet count, PLT）計數(shù)、平均血小板溶劑（mean platelet volume, MPV）、血小板壓積（platelet hematocrit, PCT）及血小板分布寬度（platelet distribution width, PDW），并進行比較。結(jié)果：40例重癥肺炎患兒中，PLT隨病情好轉(zhuǎn)而上升，PCT、MPV、PDW水平隨病情好轉(zhuǎn)而下降。急性期PLT、PCT、MPV、PDW的水平與恢復(fù)期相比，差異有統(tǒng)計學(xué)意義（Plt;0.05）。結(jié)論：動態(tài)的觀察血小板參數(shù)及其變化有助于新生兒重癥肺炎的評估及療效觀察。Abstract : Objective: To assess the relationship between neonatal severe pneumonia and platelet. Methods: We test platelet count, mean platelet volume, platelet hematocrit and platelet distribution width in 40 patients whom diagonosed neonatal svere pneumonia; moreover, we compared the platelet change in acute phase and recovery phase. Results: Mean platelet volume, platelet count increased with recovery of pneumonia (Plt;0.05). Conclusion: Observing platelet change is helpful for the evaluation of neonatal pneumonia.