【摘要】 目的 探討125I粒子植入治療中晚期胰腺癌的臨床并發(fā)癥及相關(guān)護(hù)理措施?！》椒ā』仡櫡治?006年10月-2010年4月121例行125I粒子植入治療的胰腺癌患者的臨床治療及護(hù)理，采取積極有效的護(hù)理措施，預(yù)防及處理并發(fā)癥，促進(jìn)患者康復(fù)。 結(jié)果 121例患者接受放射性125I粒子植入治療后，7例出現(xiàn)胰瘺，13例出現(xiàn)胃腸道反應(yīng)，經(jīng)對(duì)癥處理和精心護(hù)理后均治愈?！〗Y(jié)論 125I粒子組織間植入近距離治療中晚期胰腺癌近期療效好、安全、副反應(yīng)少，良好的護(hù)理對(duì)改善中晚期胰腺癌患者預(yù)后具有重要意義。【Abstract】 Objective To observe the complications in patients with middle and advanced pancreatic carcinoma due to treatment of 125I particle implantation, and the investigate the proper nursing methods. Methods The clinical data including the therapy and nursing methods for the complications in 121 patients with middle and advanced pancreatic carcinoma due to treatment of 125I particle implantation from October 2006 to October 2010 were retrospectively analyzed. The treatment and care for complication were analyzed. Results In the 121 patients who had been treated by 125I particle, pancreatic fistula occurred in seven, and severe gastrointestinal upset was found in 13. The patients with the complications recovered after postoperative treatment and nursing. Conclusion 125I particle implantation for patients with middle and advanced pancreatic carcinoma is effective and safe with a few side reactions; proper nursing is important to improve the prognosis.