• 解放軍總醫(yī)院第一附屬醫(yī)院普通外科(北京 100048);

目的  比較頸前小切口入路甲狀腺手術(shù)及改良Miccoli腔鏡輔助下甲狀腺手術(shù)治療甲狀腺良性腫瘤的療效。
方法  回顧性分析筆者所在醫(yī)院2010年1月至2012年1月期間收治的80例甲狀腺良性腫瘤患者的臨床資料,按手術(shù)方式將其分為頸前小切口組(n=40)和改良Miccoli組(n=40),比較2組患者的手術(shù)時間、術(shù)后頸部引流量、美容滿意度、住院時間、住院費用及并發(fā)癥發(fā)生率。
結(jié)果  與改良Miccoli組比較,頸前小切口組患者的手術(shù)時間較長〔(95.5±20.3) min比(62.4±15.5) min,P<0.05〕, 而美容滿意度評分〔(3.5±0.2)分比(4.3±0.1)分〕和住院費用〔(5 814.6±1 262.3)元比(9 846.7±1 080.5)元〕均較低(P<0.05); 2組患者的術(shù)后頸部引流量〔(28.6±5.5) mL比(22.2±4.5) mL〕和住院時間〔(4.5±1.5) d比(3.8±0.9) d〕 比較差異均無統(tǒng)計學意義(P>0.05)。頸前小切口組有3例患者術(shù)后出現(xiàn)聲音嘶啞,均于術(shù)后1個月左右恢復; 改良Miccoli組有1例患者術(shù)后出現(xiàn)聲音嘶啞,于術(shù)后3個月左右恢復。2組患者的喉返神經(jīng)損傷發(fā)生率比較差異無統(tǒng)計學意義(P=0.608)。2組患者均無其他手術(shù)并發(fā)癥發(fā)生。
結(jié)論  改良Miccoli腔鏡輔助下甲狀腺手術(shù)的頸部美容效果優(yōu)于頸前小切口入路手術(shù),但前者的住院費用高于后者,對美容有特殊要求或是從事特殊職業(yè)的患者可選擇性使用改良Miccoli腔鏡輔助下甲狀腺手術(shù)。

引用本文: 姚京,劉飛德,戎世捧,陳峰,朱瑛梅,姚勝. 頸前小切口入路與改良Miccoli腔鏡輔助下甲狀腺手術(shù)治療甲狀腺良性腫瘤的臨床研究. 中國普外基礎(chǔ)與臨床雜志, 2013, 20(4): 418-422. doi: 復制

1. Miccoli P, Berti P, Frustaci GL, et al. Video-assisted thyroidectomy:indications and results[J]. Langenbecks Arch Surg, 2006, 391(2):68-71.
2. 呂磊, 馬少林, 伊其忠. 美容整形受術(shù)者心理評估與術(shù)后滿意度的相關(guān)性研究[J]. 現(xiàn)代生物醫(yī)學進展, 2008, 8(1):141-143.
3. 朱利鋒, 林海平, 劉湘岳. 甲狀腺手術(shù)引流方式探討[J]. 臨床軍醫(yī)雜志, 2006, 34(2):245-246.
4. Gagner M. Endoscopic subtotal parathyroidectomy in patients with primary hyperparathyroidism[J]. Br J Surg, 1996, 83(6):875.
5. Hüscher CS, Chiodini S, Napolitano C, et al. Endoscopic right thyroid lobectomy[J]. Surg Endosc, 1997, 11(8):877.
6. Miccoli P, Pinchera A, Cecchini G, et al. Minimally invasive, video-assisted parathyroid surgery for primary hyperparathyroidism[J]. J Endocrinol Invest, 1997, 20(7):429-430.
7. 高力. Miccoli內(nèi)鏡術(shù)式與甲狀腺手術(shù)操作的微創(chuàng)化[J]. 中華外科雜志, 2006, 44(1):10-13.
8. Ikeda Y, Takami H, Tajima Gengo, et al. Direct mini-incision thyroidectomy[J]. Biomed Pharmacother, 2002, 56 Suppl 1:60s-63s.
9. 楊鵬, 牟一平, 朱玲華, 等. 內(nèi)鏡輔助下單個小切口甲狀腺手術(shù)[J]. 中國內(nèi)鏡雜志, 2006, 12(7):758-760.
10. Lombardi CP, Raffaelli M, Princi P, et al. Minimally invasive video-assisted functional lateral neck dissection for metastatic papillary thyroid carcinoma[J]. Am J Surg, 2007, 193(1):114-118.
11. Miccoli P, Berti P, Raffaelli M, et al. Minimally invasive video-assisted thyroidectomy[J]. Am J Surg, 2001, 181(6):567-570.
12. Miccoli P, Elisei R, Materazzi G, et al. Minimally invasive video-assisted thyroidectomy for papillary carcinoma:a prospective study of its completeness[J]. Surgery, 2002, 132(6):1070-1073.
13. Miccoli P, Materazzi G, Berti P. Minimally invasive video-assisted lateral lymphadenectomy:a proposal[J]. Surg Endosc, 2008, 22(4):1131-1134.
14. Shimizu K, Tanaka S. Asian perspective on endoscopic thyroidectomy—a review of 193 cases[J]. Asian J Surg, 2003, 26(2):92-100.
15. 李德祥, 王希, 陳超, 等. 非窺鏡微創(chuàng)低位小切口入路行甲狀腺手術(shù)2 336例分析[J]. 臨床和實驗醫(yī)學雜志, 2008, 7(7):148-149.
16. Roye GD, Monchik J, Amaral JF. Endoscopic adrenalectomy using ultrasonic cutting and coagulating[J]. Surg Technol Int, 2000, Ⅸ:129-138.
17. Takao S, Shinchi H, Maemura K, et al. Ultrasonically activated scalpel is an effective tool for cutting the pancreas in biliary-pancreatic surgery:experimental and clinical studies[J]. J Hepatobiliary Pancreat Surg, 2000, 7(1):58-62.
18. Kanehira E, Omura K, Kinoshita T, et al. How secure are the arteries occluded by a newly developed ultrasonically activated device?[J]. Surg Endosc, 1999, 13(4):340-342.
19. Miccoli P, Berti P, Dionigi G, et al. Randomized controlled trial of harmonic scalpel use during thyroidectomy[J]. Arch Otolaryngol Head Neck Surg, 2006, 132(10):1069-1073.
20. Siperstein AE, Berber E, Morkoyun E. The use of the harmonic scalpel vs. conventional knot tying for vessel ligation in thyroid surgery[J]. Arch Surg, 2002, 137(2):137-142.
21. Cordón C, Fajardo R, Ramírez J, et al. A randomized, prospective, parallel group study comparing the Harmonic Scalpel to electrocautery in thyroidectomy[J]. Surgery, 2005, 137(3):337-341.
22. Shemen L. Thyroidectomy using the harmonic scalpel:analysis of 105 consecutive cases[J]. Otolaryngol Head Neck Surg, 2002, 127(4):284-288.
23. Voutilainen PE, Haglund CH. Ultrasonically activated shears inthyroidectomies:a randomized trial[J]. Ann Surg, 2000, 231 (3):322-328.
24. 關(guān)強, 王貴民, 王宏升. 胸骨前徑路與改良Miccoli腔鏡甲狀腺手術(shù)臨床研究[J]. 中國普外基礎(chǔ)與臨床雜志, 2010, 17(3):240-242.
25. Owaki T, Nakano S, Arimura K, et al. The ultrasonic coagulating and cutting system injures nerve function[J]. Endoscopy, 2002, 34(7):575-579.
  1. 1. Miccoli P, Berti P, Frustaci GL, et al. Video-assisted thyroidectomy:indications and results[J]. Langenbecks Arch Surg, 2006, 391(2):68-71.
  2. 2. 呂磊, 馬少林, 伊其忠. 美容整形受術(shù)者心理評估與術(shù)后滿意度的相關(guān)性研究[J]. 現(xiàn)代生物醫(yī)學進展, 2008, 8(1):141-143.
  3. 3. 朱利鋒, 林海平, 劉湘岳. 甲狀腺手術(shù)引流方式探討[J]. 臨床軍醫(yī)雜志, 2006, 34(2):245-246.
  4. 4. Gagner M. Endoscopic subtotal parathyroidectomy in patients with primary hyperparathyroidism[J]. Br J Surg, 1996, 83(6):875.
  5. 5. Hüscher CS, Chiodini S, Napolitano C, et al. Endoscopic right thyroid lobectomy[J]. Surg Endosc, 1997, 11(8):877.
  6. 6. Miccoli P, Pinchera A, Cecchini G, et al. Minimally invasive, video-assisted parathyroid surgery for primary hyperparathyroidism[J]. J Endocrinol Invest, 1997, 20(7):429-430.
  7. 7. 高力. Miccoli內(nèi)鏡術(shù)式與甲狀腺手術(shù)操作的微創(chuàng)化[J]. 中華外科雜志, 2006, 44(1):10-13.
  8. 8. Ikeda Y, Takami H, Tajima Gengo, et al. Direct mini-incision thyroidectomy[J]. Biomed Pharmacother, 2002, 56 Suppl 1:60s-63s.
  9. 9. 楊鵬, 牟一平, 朱玲華, 等. 內(nèi)鏡輔助下單個小切口甲狀腺手術(shù)[J]. 中國內(nèi)鏡雜志, 2006, 12(7):758-760.
  10. 10. Lombardi CP, Raffaelli M, Princi P, et al. Minimally invasive video-assisted functional lateral neck dissection for metastatic papillary thyroid carcinoma[J]. Am J Surg, 2007, 193(1):114-118.
  11. 11. Miccoli P, Berti P, Raffaelli M, et al. Minimally invasive video-assisted thyroidectomy[J]. Am J Surg, 2001, 181(6):567-570.
  12. 12. Miccoli P, Elisei R, Materazzi G, et al. Minimally invasive video-assisted thyroidectomy for papillary carcinoma:a prospective study of its completeness[J]. Surgery, 2002, 132(6):1070-1073.
  13. 13. Miccoli P, Materazzi G, Berti P. Minimally invasive video-assisted lateral lymphadenectomy:a proposal[J]. Surg Endosc, 2008, 22(4):1131-1134.
  14. 14. Shimizu K, Tanaka S. Asian perspective on endoscopic thyroidectomy—a review of 193 cases[J]. Asian J Surg, 2003, 26(2):92-100.
  15. 15. 李德祥, 王希, 陳超, 等. 非窺鏡微創(chuàng)低位小切口入路行甲狀腺手術(shù)2 336例分析[J]. 臨床和實驗醫(yī)學雜志, 2008, 7(7):148-149.
  16. 16. Roye GD, Monchik J, Amaral JF. Endoscopic adrenalectomy using ultrasonic cutting and coagulating[J]. Surg Technol Int, 2000, Ⅸ:129-138.
  17. 17. Takao S, Shinchi H, Maemura K, et al. Ultrasonically activated scalpel is an effective tool for cutting the pancreas in biliary-pancreatic surgery:experimental and clinical studies[J]. J Hepatobiliary Pancreat Surg, 2000, 7(1):58-62.
  18. 18. Kanehira E, Omura K, Kinoshita T, et al. How secure are the arteries occluded by a newly developed ultrasonically activated device?[J]. Surg Endosc, 1999, 13(4):340-342.
  19. 19. Miccoli P, Berti P, Dionigi G, et al. Randomized controlled trial of harmonic scalpel use during thyroidectomy[J]. Arch Otolaryngol Head Neck Surg, 2006, 132(10):1069-1073.
  20. 20. Siperstein AE, Berber E, Morkoyun E. The use of the harmonic scalpel vs. conventional knot tying for vessel ligation in thyroid surgery[J]. Arch Surg, 2002, 137(2):137-142.
  21. 21. Cordón C, Fajardo R, Ramírez J, et al. A randomized, prospective, parallel group study comparing the Harmonic Scalpel to electrocautery in thyroidectomy[J]. Surgery, 2005, 137(3):337-341.
  22. 22. Shemen L. Thyroidectomy using the harmonic scalpel:analysis of 105 consecutive cases[J]. Otolaryngol Head Neck Surg, 2002, 127(4):284-288.
  23. 23. Voutilainen PE, Haglund CH. Ultrasonically activated shears inthyroidectomies:a randomized trial[J]. Ann Surg, 2000, 231 (3):322-328.
  24. 24. 關(guān)強, 王貴民, 王宏升. 胸骨前徑路與改良Miccoli腔鏡甲狀腺手術(shù)臨床研究[J]. 中國普外基礎(chǔ)與臨床雜志, 2010, 17(3):240-242.
  25. 25. Owaki T, Nakano S, Arimura K, et al. The ultrasonic coagulating and cutting system injures nerve function[J]. Endoscopy, 2002, 34(7):575-579.
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