【摘要】 目的 評價葛根素注射液（PI）聯(lián)合低分子肝素（LMWH）治療不穩(wěn)定型心絞痛（UAP）的療效和安全性。 方法 計算機檢索中國生物醫(yī)學文獻數(shù)據(jù)庫（CBM）、中國期刊全文數(shù)據(jù)庫（CNKI）、中文科技期刊全文數(shù)據(jù)庫（VIP-維普）、萬方-數(shù)字化期刊全文庫，納入在常規(guī)治療上加用PI和LMWH對比單純常規(guī)治療的隨機對照試驗（RCT），對納入研究進行質(zhì)量評價和Meta分析。 結(jié)果 共納入21個RCT，均為C級文獻。Meta分析結(jié)果顯示，在臨床癥狀療效顯效率、心電圖療效顯效率和有效率指標方面，兩組差異有統(tǒng)計學意義:RR（95%CI）分別為:1.63（1.48，1.79）、1.57（1.34，1.83）及1.28（1.10，1.49）。 結(jié)論 基于上述證據(jù)，在常規(guī)治療UAP上加用PI和LMWH療效優(yōu)于常規(guī)治療。【Abstract】 Objective To evaluate the effect of the puerarin injection (PI) combined with low molecular weight heparins (LMWH) on unstable angina pectoris (UAP). Methods Randomized controlled trials (RCT) of PI combined with LMWH treating UAP were gathered from CBM, CNKI, VIP, and Wanfang data bases; and study quality was evaluated and the Meta-analysis was carried out. Results A total of 21 RCT were identified, of which all were in graded C. According to Meta-analysis, the differences of the clinic excellent rate, electrocardiogram excellent rate and effective rate between the two groups were significant; the RR (95%CI) were: 1.63 (1.48, 1.79), 1.57 (1.34, 1.83), and 1.28 (1.10, 1.49). Conclusion Based on the evidence recently, PI and LMWH adding is better than ordinary treatment for UAP.